Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0233565 (bradykinesia)
2,352 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 149 MRI 116 tyrosine hydroxylase 64 synuclein 52 She 51 Mol 46 alpha-synuclein 39 dopamine transporter 35 olfactory 32 CIT 29 LRRK2 22 Pol 22 asymmetrical 21 DBS 21 GABA 21 ubiquitin 20 STN 20 axonal 19 caspase-3 17 MAO-B 17 MDS 16 parkin 14 tau protein 13 PSP 12 glial cell line-derived neurotrophic factor 12 CSF 12 REM 11 Bcl-2 10 SNCA 10 PINK1 10 tap 10 DJ-1 10 ATP 9 MPP 9 proteasome 9 leucine-rich repeat kinase 2 9 with Parkinsonism 9 MSA 8 SCH 8 COMT 8 dopa decarboxylase 8 catechol-O-methyltransferase 8 5-HT1A 7 ANOVA 7 DAT 7 PARK7 7 glial fibrillary acidic protein 7 ACS 7 gut 7 Parkin 7 glucocerebrosidase 6 dopamine D2 receptor 6 endoplasmic reticulum 6 ATP13A2 6 superoxide dismutase 6 ferritin 6 beta-endorphin 6 dopa-responsive dystonia 6 GSH 6 ceruloplasmin 6 substance P 6 FDG 5 acetylcholinesterase 5 PTEN 5 prolactin 5 lipopolysaccharide 5 cytochrome c 5 ATPase 5 sit 5 ADL 5 glutamic acid decarboxylase 5 methyltransferase 5 DRD2 5 amyloid precursor protein 5 vesicular monoamine transporter 2 5 D2 dopamine receptor 4 p38 4 SOD2 4 HT3 4 DCI 4 more...

Disease Parkinson's disease 1684 parkinsonism 526 dementia 226 akinesia 175 dyskinesia 174 depression 166 cognitive impairment 122 movement disorder 122 Alzheimer's disease 106 progressive supranuclear palsy 89 Huntington's disease 76 psychosis 65 hallucinations 48 apraxia 43 dysphagia 38 sleep disorders 31 sleep disturbances 30 stroke 28 catalepsy 27 Dementia with Lewy bodies 24 encephalopathy 22 neurological disease 22 incontinence 21 schizophrenia 21 encephalitis 20 REM sleep behavior disorder 18 epilepsy 18 myelodysplastic syndrome 16 hemiparkinsonism 16 MDS 16 Wilson's disease 14 hemiparesis 14 disorientation 14 mutism 14 confusion 14 tardive dyskinesia 13 pneumonia 13 amyotrophic lateral sclerosis 13 memory impairment 13 diabetes 13 abnormal involuntary movements 13 delusions 13 hydrocephalus 12 PSP 12 dysautonomia 12 coma 12 aphasia 12 disinhibition 11 mental illness 10 tumor 10 Dystonia 10 brain atrophy 10 incontinence 10 hypertension 10 pseudobulbar palsy 10 Creutzfeldt-Jakob disease 9 aspiration pneumonia 9 restless legs syndrome 9 nystagmus 8 Multiple system atrophy 8 SCH 8 MSA 8 aggression 8 systemic lupus erythematosus 8 immunodeficiency 7 olivopontocerebellar atrophy 7 choreoathetosis 7 Brown 7 major depressive disorder 7 multiple sclerosis 7 ischemia 7 Machado-Joseph disease 7 vascular disease 6 Corticobasal degeneration 6 camptocormia 6 PAF 6 motor neuron disease 6 sexual dysfunction 6 behavior disorder 6 muscular atrophy 6 more...

Symptom bradykinesia 2352 tremor 1251 dystonia 167 muscle rigidity 93 ataxia 69 dysarthria 67 chorea 51 motor symptom 47 myoclonus 39 pain 38 weakness 33 seizures 32 constipation 29 apathy 28 abnormal gait 28 sleepiness 27 fatigue 25 spasticity 24 cerebellar ataxia 22 insomnia 20 nausea 17 memory loss 14 ophthalmoplegia 13 agitation 12 headache 12 Rest tremor 12 vomiting 11 Extrapyramidal symptoms 10 Decreased activity 8 blepharospasm 8 dizziness 8 paresis 7 catatonia 7 paraparesis 7 anesthesia 7 clumsiness 7 incoordination 7 hypertonia 7 functional recovery 6 Involuntary Movement 6 dyspnea 6 drooling 6 pallor 6 discomfort 5 hypothermia 5 discomfort 5 ataxic gait 5 excessive sweating 4 muscle stiffness 4 anorexia 4 anosmia 4 torticollis 4 paresthesia 4 lethargy 4 personality change 3 myalgia 3 nausea and vomiting 3 fasciculation 3 thinning 3 eds 3 consciousness disturbance 3 hypotonia 3 dysuria 3 stridor 3 athetosis 3 forgetfulness 3 vertigo 3 cachexia 2 tonic-clonic seizure 2 Postural tremor 2 hemiplegia 2 respiratory distress 2 spasm 2 numbness 2 syncope 2 exhaustion 2 asthenia 2 cough 2 asterixis 2 Sedation 2 more...

Drug DBS 21 Sinemet 18 MDS 16 Sinemet 15 Sinemet 15 CSF 12 Parkin 7 Posture 7 Parkin 7 Apomorphine 6 Madopar 4 Parlodel 4 caffeine 4 vitamin E 3 Parlodel 3 ascorbate 3 Lisuride 3 Frontal 3 Carbidopa 3 Rasagiline 3 Lergotrile 2 Blonanserin 2 CFT 2 niacin 2 ICI 2 ROS 2 Portal 2 Benserazide 2 Lergotrile mesylate 1 Bupleurum root 1 TMS 1 Android 1 Tianma 1 Pramipexole 1 Pramipexole 1 MAP 1 CTX 1 citric acid 1 Tocopherol 1 NADH 1 Dophamine 1 Azilect 1 3,4-Dihydroxyphenylalanine 1 Spectrum 1 Dakar 1 Triclosan 1 Flunarizine hydrochloride 1 CTX 1 Primperan 1 Succinobucol 1 CTX 1 Rosin 1 DM1 1 Sodium benzoate 1 Eldepryl 1 Reserpine 1 Topamax 1 Istradefylline 1 Metoclopramide hydrochloride 1 HCG 1 Safflower 1 Tandospirone citrate 1 ENT 1 Monit 1 uPA 1 Diurnal 1 Droxidopa 1 PCP 1 Eldepryl 1 Mirapex 1 Bupivacaine 1 NVP 1 Moclobemide 1 ROC 1 pyridoxal phosphate 1 Donepezil 1

Enzyme tyrosine hydroxylase 63 monoamine oxidase 28 caspase-3 17 acetylcholinesterase 10 proteasome 10 superoxide dismutase 9 MPP 9 protein kinase 7 ACS 7 DAT 7 ceruloplasmin 6 complex I 6 mitogen-activated protein kinase 6 cholinesterase 6 catalase 5 ERK 5 ATPase 5 pantothenate kinase 4 caspase-9 3 DOPA decarboxylase 3 glutathione peroxidase 3 catechol O-methyltransferase 3 heme oxygenase 3 phosphodiesterase 2 AMPK 2 protein kinase C 2 peroxidase 2 beta-galactosidase 2 choline acetyltransferase 2 GSK 2 AMPK 2 AMP-activated protein kinase 2 FAST 1 glutathione reductase 1 MAP 1 MEK 1 lactate dehydrogenase 1 phosphatidylinositol 3-kinase 1 NADPH oxidase 1 hexosaminidase 1 aldehyde dehydrogenase 1 isopeptidase 1 creatine kinase 1 CD10 1 proteinase K 1 phosphoglycerate kinase 1 PCP 1 glyceraldehyde-3-phosphate dehydrogenase 1 P-glycoprotein 1 tissue plasminogen activator 1 succinate dehydrogenase 1 cathepsin B 1 paraoxonase 1 guanylate cyclase 1 PKG 1 urokinase-type plasminogen activator 1 calcineurin 1 NOS 1 transglutaminase 1 nicotinamide N-methyltransferase 1 granzyme B 1 cyclohydrolase 1 PAL 1 papain 1 PDE 1 GD3 synthase 1 GABA transaminase 1 PAL 1 Thy1 1 MEKK1 1 PARP 1 myrosinase 1 paraoxonase 1 NADPH oxidase 1 Alternating 1 aldehyde oxidase 1 CNPase 1 glucocerebrosidase 1

Compound L-DOPA 161 Dec 153 Clin 140 MPTP 135 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 86 Dopamine 41 His 35 glutamate 31 CIT 29 CIT 29 oxygen 27 manganese 26 iron 23 GABA 21 DBS 21 GABA 21 water 19 DNA 18 calcium 17 5-HT 16 Dopa 14 glucose 13 noradrenaline 13 Neuronal 12 PSP 12 4-phenyl-1,2,3,6-tetrahydropyridine 11 Bromocriptine 10 nitric oxide 9 MPP 9 MPP 9 ATP 9 PDQ 8 potassium 8 gamma-aminobutyric acid 7 NMDA 7 ACS 7 ACS 7 DAT 7 copper 7 Haloperidol 6 GSH 6 Haloperidol 6 cAMP 6 DSM 6 GSH 6 sodium 5 Amantadine 5 caffeine 5 ethanol 5 Amantadine 5 Amantadine 5 3,4-dihydroxyphenylalanine 5 iodine 5 tyrosine 5 Rotenone 5 Amantadine 5 silver 4 cysteine 4 sulfate 4 DCI 4 Nicotine 4 galactose 4 Ropinirole 4 Selegiline 4 GTP 4 IMP 3 MDA 3 acetic acid 3 coenzyme Q10 3 arginine 3 alanine 3 methanol 3 valine 3 serine 3 CO2 3 Letter 3 Morphine 3 mercury 3 1,2,3,4-tetrahydroisoquinoline 3 creatinine 3 more...

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