Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0233565 (bradykinesia)
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Human Gene/Protein
KIAA1024L 13.7
BBG-TCC 12.7
USP31 10.7
ATP1B4 10.7
phosphodiesterase 8B 10.4
SNCAIP 9.7
CHD6 9.6
ANO10 9.6
STX6 9.5
NMD3 9.4
Kufor-Rakeb syndrome 9.2
IRX2 9.1
PANK2 9.1
HNMT 9.0
Synaptojanin 1 9.0
calmodulin-like skin protein 8.9
with Parkinsonism 8.8
CHCHD2 8.8
CIT 8.7
vacuolar protein sorting 35 8.7
ATP13A2 8.7
F-box only protein 7 8.7
Alpha synuclein 8.7
PARK8 8.7
PKAN 8.7
STN 8.6
SCA8 8.6
Hallervorden-Spatz syndrome 8.6
USP30 8.5
KCNJ6 8.5
SCA17 8.5
EIF4G1 8.4
DYT11 8.4
STK39 8.4
DBS 8.3
LRRK2 8.3
MOBP 8.2
PRKACB 8.2
Dopamine transporter 8.1
SV2C 8.1
MUL1 8.1
PARK7 8.1
SLC18A2 8.0
dopa-responsive dystonia 8.0
DCI 8.0
AFG3L2 7.9
iron regulatory protein 2 7.9
leucine-rich repeat kinase 2 7.6
SNCA 7.6
Engrailed-2 7.6
alpha synuclein 7.6
HTR2C 7.5
PSP 7.5
GPR37 7.5
TMEM106B 7.4
NADH: ubiquinone oxidoreductase 7.4
5-HT-1A 7.4
PABP1 7.3
Leucine-rich repeat kinase 2 7.3
Monoamine oxidase B 7.3
pantothenate kinase 7.3
RET protein 7.3
TRIM24 7.2
GCH1 7.2
5-HT6 7.2
PARK6 7.2
CHMP2B 7.2
parkin 7.2
spinocerebellar ataxia type 2 7.2
colony stimulating factor 1 receptor 7.2
SCA2 7.2
catechol O-methyltransferase 7.2
glial cell derived neurotrophic factor 7.1
amylase 1 7.1
DTN 7.1
Frataxin 7.1
ddc 7.0
MSA 7.0
synuclein 7.0
N33 7.0
alpha-synuclein 7.0
PARKIN 7.0
Arylsulfatase A 6.9
EIF2AK3 6.9
MFT 6.8
synphilin-1 6.8
SCA1 6.8
DUSP5 6.8
IRP2 6.8
TAC1 6.8
IRP1 6.7
dopamine transporter 6.7
DJ-1 6.7
SRO 6.7
PINK1 6.7
PPX 6.7
MDS 6.6
ATP1A3 6.5
SCA3 6.5
MAO-B 6.5
GD3 synthase 6.5
OMD 6.5
SLC6A3 6.5
mGluR4 6.4
jerky 6.4
hnRNPA1 6.4
SIRT5 6.4
neurturin 6.4
COMT 6.4
PSG 6.3
NST 6.3
ferroportin 1 6.3
IPT 6.3
SYP 6.2
Nicotinamide N-methyltransferase 6.2
VMAT2 6.2
VPS35 6.2
TH protein 6.2
RARS 6.2
S100beta 6.2
MPP 6.2
MAOB 6.1
vesicular monoamine transporter 2 6.1
Presenilin 1 6.1
glial cell line-derived neurotrophic factor 6.1
NRM 6.1
Interleukin 4 6.1
DAT 6.0
catechol-O-methyltransferase 5.9
NFKBIA 5.9
GCH 5.9
NR4A2 5.9
ubiquitin C-terminal hydrolase 5.9
UCHL1 5.9
AG1 5.9
MTH1 5.9
SUMO-2 5.9
GRN 5.9
malin 5.9
DRD2 5.9
PSEN1 5.9
HS3 5.8
NRG 5.8
tyrosine hydroxylase 5.8
transferrin receptor 2 5.8
UCH-L1 5.8
leucine-rich repeat protein 5.8
SWI2 5.8
PARK2 5.8
BBS 5.8
ENA 5.7
dopa decarboxylase 5.7
GPE 5.7
HLA-B51 5.7
nuclear respiratory factor 1 5.7
activator 1 5.7
Parkin 5.7
HDS 5.7
tre 5.6
neurotrophin-4 5.6
nociceptin receptor 5.6
mitogen-activated protein kinase kinase kinase 5.6
PRNP 5.5
TUG 5.5
nephropathic cystinosis 5.5
ataxin-3 5.5
GABARAP 5.5
Prion protein 5.5
RGS2 5.4
HNF4A 5.4
Catechol-O-methyltransferase 5.4
CSF1R 5.4
TARDBP 5.4
synaptotagmin I 5.4
CLN 5.4
D2 dopamine receptor 5.4
CBD 5.4
SUMO-1 5.4
BPP 5.3
P45 5.3
COPE 5.3
NT-4/5 5.3
glucocerebrosidase 5.3
ADL 5.3
TDT 5.3
14-3-3 protein 5.3
GDNF 5.3
NOTCH2 5.3
DRD3 5.3
PIF 5.2
CHAC 5.2
allele 2 5.2
VGLUT2 5.2
HTR2A 5.2
ATX 5.2
MUTYH 5.1
tau protein 5.1
CACNA1A 5.1
VGLUT1 5.1
dopamine D2 receptor 5.1
apoptosis-related protein 5.1
EPM 5.0
RGS4 5.0
OGG1 5.0
SOD2 5.0
DSP-4 5.0
DDC 5.0
TATA-binding protein 5.0
LIN28 5.0
NOTCH3 4.9
activating transcription factor 3 4.9
H-Y 4.9
ABS 4.9
mGlu5 4.9
Trap 4.9
CLN3 4.8
SCA6 4.8
divalent metal transporter 1 4.8
dopamine D3 receptor 4.8
IPL 4.8
MAO A 4.8
SLAM-associated protein 4.7
REM 4.7
VIM 4.7
SNF2 4.7
HPD 4.7
BDS 4.7
MAO B 4.7
FTD 4.7
NADPH oxidase 2 4.7
HO-2 4.7
Tic 4.7
HtrA 4.6
TAU 4.6
PPN 4.6
NFKB1 4.6
Thyrotropin-releasing hormone 4.6
OCT3 4.6
RAC 4.6
SLC6A4 4.6
fibronectin mRNA 4.6
aquaporin 4 4.6
asymmetrical 4.5
PSD 4.5
HTT 4.5
LBD 4.5
TDP-43 4.5
NF-M 4.5
SCN1A 4.5
IRP 4.4
CNPase 4.4
OFQ 4.4
HT3 4.4
NMS 4.4
SCH 4.4
C9orf72 4.4
complex I) 4.4
PMC 4.4
progranulin 4.3
Wilson disease 4.3
mitochondrial transcription factor A 4.3
LRP5 4.3
frataxin 4.3
constitutive nitric oxide synthase 4.3
ceruloplasmin 4.3
BACE 4.3
ChAT 4.3
NF-H 4.3
Cholinesterase 4.2
TRA 4.2
5-HT receptor 4.2
5-HT4 4.2
prodynorphin 4.2
FAST 4.2
NF-L 4.2
MRI 4.2
Dance 4.2
glutamate binding 4.2
dynamin-related protein 1 4.1
glutamic acid decarboxylase 4.1
CDC42 4.1
MAG 4.1
eukaryotic translation initiation factor 4.1
GABA transaminase 4.1
Transporter 4.1
aldehyde oxidase 4.1
huntingtin 4.1
5-HT1A 4.1
GIT 4.1
lipoprotein receptor-related protein 4.1
SERT 4.1
neuronal protein 4.0
DMPK 4.0
5-HT2A 4.0
norepinephrine transporter 4.0
MECP2 4.0
GSD 4.0
delta opioid receptor 4.0
microtubule associated protein 4.0
GM-CSF receptor 4.0
PSE 3.9
netrin-1 3.9
PEF 3.9
hereditary hemochromatosis 3.9
Vasoactive intestinal peptide 3.9
ECD 3.9
VCP 3.9
brain protein 3.9
GAD 3.9
ARC 3.8
LAMP 3.8
GLAST 3.8
glucose-dependent insulinotropic polypeptide 3.8
PUMA 3.8
DA transporter 3.8
ULK1 3.8
IMP 3.8
FMRP 3.7
dominant) 3.7
Interleukin-3 3.7
C protein 3.7
Smac 3.7
FTA 3.7
Apaf-1 3.7
MEKK 3.7
A11 3.7
DRS 3.6
She 3.6
CS2 3.6
PAL 3.6
P25 3.6
sit 3.6
manganese superoxide dismutase 3.6
presenilin 1 3.6
DMD 3.6
olfactory 3.6
SMC 3.5
SDH 3.5
c-Rel 3.5
FUS 3.5
neurotrophic factor 3.5
GAD67 3.5
CCT 3.5
version 3 3.5
GLT-1 3.5
tPA 3.5
NG2 3.4
CGI 3.4
NET 3.4
FAM 3.4
transforming growth factor beta 1 3.4
HO-1 3.4
PLP 3.4
dopamine D1 receptor 3.4
mGluR5 3.4
CHD 3.3
GAD65 3.3
SMS 3.3
tap 3.3
Caspase-1 3.3
SOX2 3.3
p23 3.3
FMR1 3.3
paraoxonase 3.2
ROM 3.2
IgH 3.1
CAL 3.1
p47 3.1
phosphoglycerate kinase 3.1
BRL 3.1
MCP 3.1
alpha 4 3.1
p19 3.1
MRS 3.1
ubiquitin 3.1
GABA 3.1
TAP 3.0
HFE 3.0
adenosine A1 receptor 3.0
WIN 3.0
cystatin C 3.0
KDR 3.0
DM1 3.0
pyrin 3.0
PrP 3.0
CRT 2.9
GAP-43 2.9
Nestin 2.9
RACE 2.9
PTEN 2.9
MIM 2.9
NR2A 2.9
Nrf2 2.9
heat shock protein 90 2.9
novel gene 2.9
serotonin transporter 2.8
DNA binding protein 2.8
5-HTTLPR 2.8
neurotrophin-3 2.8
CSF 2.8
calpain 2.8
SCL 2.8
ornithine transcarbamylase 2.7
SMA 2.7
X-linked recessive 2.7
CA2 2.7
Dakar 2.7
metabotropic glutamate receptor 2.7
dynorphin 2.7
DAF 2.7
serotonin receptor 2.7
DNA-binding protein 2.7
Ubiquitin 2.6
MBP 2.6
CREB 2.6
FDG 2.6
STS 2.6
TMS 2.6
Q10 2.6
methyltransferase 2.6
guanylyl cyclase 2.6
axonal 2.6
nicotinic acetylcholine receptor 2.5
PDE 2.5
GAPDH 2.5
glial fibrillary acidic protein 2.5
Beclin-1 2.5
hemochromatosis 2.5
prion protein 2.5
c-Met 2.5
PSD-95 2.5
mouse) 2.4
PKG 2.4
glutamate transporter 2.4
enigma 2.4
MYC 2.4
HNE 2.4
Del 2.4
HCG 2.4
proline-rich 2.4
amyloid beta 2.3
ANA 2.3
caspase-3 2.3
ART 2.3
APOE 2.3
GABA(A) receptor 2.3
B19 2.3
Nanog 2.3
insulin-like growth factor 1 2.3
SIV 2.3
MnSOD 2.3
NR2B 2.3
proteasome 2.2
heme oxygenase-1 2.2
ferritin 2.2
Rett syndrome 2.2
GSK 2.2
interferon alpha 2.1
synaptophysin 2.1
PFC 2.1
Oct4 2.1
choline acetyltransferase 2.1
AMPK 2.1
N-acetylaspartate 2.1
SPL 2.1
prion 2.1
caspase-9 2.1
ANOVA 2.1
RET 2.0
transferrin receptor 2.0
ALS 2.0
Bcl-2 2.0
dynamin 2.0
neutral endopeptidase 2.0
CBS 2.0
beta-endorphin 2.0
substance P 1.9
FAB 1.9
cannabinoid receptor 1.9
galanin 1.9
14-3-3 1.9
amyloid precursor protein 1.9
transglutaminase 1.9
Smad3 1.9
CCK 1.9
PCP 1.9
granzyme B 1.9
PKA 1.8
SNAP 1.8
PGC 1.8
glutamate receptor 1.8
strabismus 1.8
H2AX 1.8
natural killer cell 1.8
pyruvate dehydrogenase 1.8
KIT 1.7
cathepsin B 1.7
GFR 1.7
X-linked 1.7
NLRP3 1.7
anonymous 1.7
SWI 1.7
acetylcholinesterase 1.6
cysteine protease 1.6
adenosine receptor 1.6
neuronal nitric oxide synthase 1.6
adrenocorticotropic hormone 1.6
APP 1.6
PPAR 1.5
P300 1.5
poly(ADP-ribose) polymerase 1.5
homeobox 1.5
proteasome inhibitor 1.5
cytochrome c 1.5
vasoactive intestinal peptide 1.5
5-hydroxytryptamine 1.5
brain-derived neurotrophic factor 1.4
PLC 1.4
rat) 1.4
perforin 1.3
NMDA receptor 1.3
A431 1.3
fur 1.3
CD68 1.3
CTX 1.2
prolactin 1.2
cyclooxygenase-2 1.2
ferredoxin 1.1
Pol 1.1
plasminogen activator inhibitor-1 1.1
GSH 1.1
PKC 1.0
inducible nitric oxide synthase 1.0
LC3 1.0
NOD 1.0
hepatocyte growth factor 1.0
ionotropic 1.0
reserved 1.0
SOD 1.0
GTP 1.0
protein phosphatase 1.0
sodium channel 1.0
MAP 0.9
glutathione peroxidase 0.9
cytochrome 0.9
transmembrane protein 0.9
interacting protein 0.9
p38 0.9
follicle-stimulating hormone 0.9
cage 0.9
apolipoprotein E 0.9
macrophage colony-stimulating factor 0.8
alpha-fetoprotein 0.8
CRP 0.8
p27 0.8
PI3K 0.8
HEK 0.8
transforming growth factor-beta 0.8
antioxidant enzyme 0.8
lamp 0.7
superoxide dismutase 0.7
CXCR4 0.7
CD20 0.7
helicase 0.6
B12 0.6
unknown function 0.6
adenylyl cyclase 0.6
phosphodiesterase 0.6
CAT 0.6
San 0.6
transferrin 0.6
neuropeptide Y 0.5
annexin V 0.5
receptor tyrosine kinase 0.5
cardiac muscle 0.5
glutathione reductase 0.5
ROS 0.5
nitric oxide synthase 0.4
urokinase-type plasminogen activator 0.4
plasminogen 0.4
gut 0.4
LDH 0.4
histone H3 0.4
endoplasmic reticulum 0.3
PARP 0.3
cyclin 0.3
cholecystokinin 0.3
phosphatidylinositol 3-kinase 0.3
ACS 0.3
c-fos 0.3
histone deacetylase 0.3
ERK1 0.3
nodal 0.2
c-Jun 0.2
AKT 0.2
catalase 0.2
proteoglycan 0.2
ATPase 0.2
extracellular signal-regulated kinase 0.2
Mot 0.1
lipopolysaccharide 0.1
MEK 0.1
ERK 0.0
P-glycoprotein 0.0
Sep -0.0
Mol -0.0
GTPase -0.1
TGF-beta -0.1
ATP -0.1
UTR -0.2
calcium channel -0.2
MAPK -0.2
myeloperoxidase -0.2
TLR4 -0.3
thyroid hormone -0.3
JNK -0.3
parathyroid hormone -0.3
telomeric -0.3
Met -0.4
p53 -0.5
NAD -0.6
kit -0.6
MHC -0.7
NADH -0.7
somatostatin -0.7
interleukin-6 -0.8
C-reactive protein -0.9
calmodulin -0.9
cytochrome P450 -0.9
mTOR -0.9
lactate dehydrogenase -1.0
estrogen receptor -1.0
phosphatase -1.1
fused -1.1
IL-6 -1.1
membrane-bound -1.1
hole -1.1
growth hormone -1.1
albumin -1.2
vascular endothelial growth factor -1.2
more...
Disease
early parkinson's 13.7
Pallidonigral degeneration 13.7
Bradyphrenia 13.1
Supranuclear gaze palsy 12.7
CRCL 12.1
SCAR6 12.1
Secondary parkinsonism 11.9
Vascular parkinsonism 11.7
PARK12 11.4
Striatonigral degeneration 11.3
SCA21 11.1
Vertical gaze palsy 10.7
PARK3 10.6
hemiparkinsonism 10.3
organic delusional syndrome 10.3
Ideational apraxia 10.3
CNS degenerative disease 10.3
Juvenile Parkinsonism 10.3
organic personality syndrome 10.0
mild memory disturbance 10.0
Parkinson's disease and parkinsonism 10.0
akinesia 10.0
Ideomotor apraxia 9.8
Corticobasal degeneration 9.6
Cerebellar degeneration 9.3
REM sleep behavior disorder 9.1
camptocormia 9.0
PARK8 9.0
parkinsonism 8.9
dysbasia 8.9
Progressive dementia 8.9
pseudobulbar palsy 8.9
dyskinesia 8.8
anarthria 8.6
extrapyramidal disorder 8.6
movement disorder 8.5
Parkinson's disease 8.5
DYT11 8.5
progressive supranuclear palsy 8.5
SCA17 8.4
basal ganglia disease 8.4
Hallervorden-Spatz disease 8.4
abnormal involuntary movements 8.1
Cranial nerves 8.0
Cranial nerves 8.0
Multiple system atrophy 8.0
Pontocerebellar hypoplasia 8.0
KRS 7.9
SCA8 7.8
impulse control disorder 7.8
delusions of persecution 7.8
psycho-organic syndrome 7.8
apraxia 7.7
Globus 7.7
Demented 7.7
Dementia with Lewy bodies 7.6
Dystonia 7.6
olivopontocerebellar atrophy 7.6
PSP 7.5
Pure autonomic failure 7.5
adult HD 7.5
cerebral degeneration 7.4
mutism 7.4
dysautonomia 7.4
Essential tremor 7.4
choreoathetosis 7.3
autonomic disorder 7.3
PARK7 7.3
catalepsy 7.3
Cerebral metastases 7.2
Autoimmune encephalitis 7.1
SCA2 7.1
flat affect 7.1
Binswanger 7.1
encephalomyelopathy 7.1
PARK6 7.0
primary lateral sclerosis 7.0
MSA 7.0
blunted affect 6.8
motor aphasia 6.8
DRD 6.8
pediatric HD 6.8
TSH deficiency 6.8
HIV encephalopathy 6.8
SCA1 6.7
Machado-Joseph disease 6.7
Parinaud's syndrome 6.7
acanthocytosis 6.7
Neurodegenerative Disorders 6.6
Meige syndrome 6.6
acalculia 6.6
actinomycetoma 6.5
hemichorea 6.5
Ritual 6.5
Familial hemiplegic migraine 6.5
MDS 6.5
hallucinations 6.4
Frontotemporal dementia 6.4
behavior disorder 6.4
intellectual impairment 6.3
cognitive disorder 6.3
retrobulbar neuritis 6.3
anomia 6.3
Wilson's disease 6.3
cerebellar syndrome 6.2
Huntington's disease 6.2
echolalia 6.2
Toxoplasma encephalitis 6.2
disorientation 6.2
sleep disturbances 6.2
vCJD 6.2
Fahr's disease 6.1
Spinocerebellar ataxia 6.1
tardive dyskinesia 6.1
FTLD 6.1
agnosia 6.1
Pick's disease 6.1
Inborn errors of metabolism 6.1
public drinking 6.1
Lissauer 6.0
SCA6 6.0
Neonatal sepsis 6.0
speech disorder 6.0
restless legs syndrome 6.0
hypoadrenocorticism 6.0
Herpes simplex encephalitis 6.0
sleep disorders 5.9
NMS 5.9
asthenopia 5.9
Akathisia 5.9
GM2 gangliosidosis 5.8
torsion dystonia 5.8
dementia 5.8
Lower limb 5.7
aspiration pneumonia 5.7
PARK2 5.7
visual dysfunction 5.7
chondritis 5.7
reactive depression 5.7
complete paraplegia 5.6
Relapsing polychondritis 5.6
brain disorder 5.5
BPP 5.5
RARS 5.5
GM1 gangliosidosis 5.5
cognitive impairment 5.5
sensory disturbance 5.5
Canavan 5.5
polychondritis 5.5
dyscalculia 5.4
primary central nervous system lymphoma 5.4
Nystagmus 5.4
presenile dementia 5.4
seborrheic dermatitis 5.3
Abdomen 5.3
HIV encephalitis 5.3
AIDS dementia complex 5.3
parasomnia 5.3
Gerstmann 5.3
melancholia 5.2
frozen shoulder 5.2
dysphasia 5.2
Vascular dementia 5.2
organic brain syndrome 5.2
SIADH 5.2
stereotypies 5.1
leukoencephalopathy 5.1
labyrinthitis 5.1
hypersexuality 5.1
FFI 5.1
emotional instability 5.1
dysphagia 5.0
neurological disease 5.0
disinhibition 5.0
Iodine deficiency 5.0
CAA 5.0
gangliosidosis 4.9
gastrointestinal dysfunction 4.9
Cerebellum 4.9
ABS 4.9
neurogenic bladder 4.9
psychosis 4.9
PMC 4.9
drug withdrawal 4.9
quadriparesis 4.8
degenerative disease 4.8
hemiparesis 4.8
delusions 4.8
Creutzfeldt-Jakob disease 4.8
ABS 4.8
motor neuron disease 4.8
brain atrophy 4.8
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 4.8
CAA 4.8
Sandhoff disease 4.8
Depressive disorders 4.8
neuromyotonia 4.8
agraphia 4.8
PAF 4.7
anhidrosis 4.7
Spencer 4.7
stuttering 4.7
LBD 4.7
neuronal ceroid lipofuscinosis 4.7
lens opacity 4.7
Tourette syndrome 4.7
Neurocysticercosis 4.7
Mycoplasma pneumoniae pneumonia 4.6
regional pain syndrome 4.6
Japanese encephalitis 4.6
CJD 4.6
memory impairment 4.6
hepatic coma 4.6
seborrheic keratosis 4.6
lymphomatoid granulomatosis 4.6
aphasia 4.6
blood disorder 4.6
disabling disease 4.5
cystinosis 4.5
ventriculitis 4.5
NMS 4.5
hereditary hemochromatosis 4.4
Behcet's disease 4.4
SCH 4.4
incontinence 4.4
PDP 4.4
EPS 4.3
dysthymia 4.3
kernicterus 4.3
sexual dysfunction 4.3
scleritis 4.3
Tic 4.3
ERS 4.2
paranoid schizophrenia 4.2
EPS 4.2
meningococcal meningitis 4.2
rosacea 4.1
tic 4.1
Sleep disturbance 4.1
multiple disorders 4.1
cognitive deficit 4.1
CLN3 4.1
DWI 4.1
myelitis 4.1
encephalopathy 4.0
Bardet-Biedl syndrome 4.0
NPH 4.0
Guillain-Barre syndrome 4.0
incontinence 4.0
anhedonia 3.9
pseudohypoparathyroidism 3.9
vitamin E deficiency 3.9
impotence 3.9
encephalitis 3.9
nystagmus 3.9
myelodysplastic syndrome 3.9
aseptic meningitis 3.8
mental handicap 3.8
neurosyphilis 3.8
self-injurious behavior 3.8
musculoskeletal disease 3.8
Gaucher disease 3.8
subacute sclerosing panencephalitis 3.7
depression 3.7
Alzheimer's disease 3.7
Friedreich's ataxia 3.7
protein deficiency 3.7
GCE 3.7
Angelman syndrome 3.7
ventricular dilatation 3.6
hepatic encephalopathy 3.6
PAL 3.6
amnesia 3.6
mitochondrial myopathy 3.6
perseveration 3.6
SMC 3.6
pathological gambling 3.6
bruxism 3.6
ICC 3.6
hydrocephalus 3.5
FUS 3.5
ICC 3.5
arteriovenous malformation 3.5
nocturia 3.5
hypopituitarism 3.5
unipolar depression 3.4
GAD 3.4
metachromatic leukodystrophy 3.4
spongiform encephalopathy 3.4
coma 3.4
paranoia 3.4
muscular atrophy 3.3
hygroma 3.3
gastroparesis 3.3
PML 3.3
PDD 3.3
DM1 3.3
spastic paraplegia 3.2
tetraplegia 3.2
amyotrophic lateral sclerosis 3.2
porphyria 3.2
delirium 3.2
DRS 3.1
confusion 3.1
senile dementia 3.1
Raynaud 3.1
MRS 3.1
paraneoplastic syndrome 3.1
tonsillitis 3.1
otitis 3.1
Tay-Sachs disease 3.1
SMS 3.0
oligodendroglioma 3.0
craniopharyngioma 3.0
hemochromatosis 3.0
erectile dysfunction 3.0
Brown 2.9
azotemia 2.9
mitochondrial disease 2.9
scrapie 2.8
NBS 2.8
neuritis 2.8
uremia 2.8
sleep apnea 2.8
ketosis 2.7
CTX 2.7
congenital hypothyroidism 2.7
iron overload 2.7
Horner's syndrome 2.7
meningioma 2.7
dysphonia 2.7
peripheral neuropathy 2.7
meningoencephalitis 2.7
conduct disorder 2.7
fecal incontinence 2.6
keratosis 2.6
bronchopneumonia 2.6
malignant hyperthermia 2.5
toxoplasmosis 2.5
iron deficiency 2.5
HTLV-I 2.5
brain tumor 2.5
Sweet 2.4
STS 2.4
diplopia 2.4
PDE 2.4
CNS diseases 2.4
ECT 2.4
polyneuropathy 2.4
germ cell tumor 2.4
telangiectasia 2.4
obsessive-compulsive disorder 2.4
optic neuritis 2.3
HAM 2.3
hypoparathyroidism 2.3
pituitary tumor 2.3
parasitic disease 2.3
brain dysfunction 2.3
affective disorder 2.3
vascular disease 2.3
schizophrenia 2.2
prolapse 2.2
mental illness 2.1
Cannabis 2.1
major depressive disorder 2.1
binge eating 2.1
pemphigoid 2.1
Delhi 2.0
Rett syndrome 2.0
adrenal insufficiency 2.0
obstructive sleep apnea 2.0
pulmonary fibrosis 1.9
fragile X syndrome 1.9
epilepsy 1.9
aggression 1.9
warts 1.9
Dissociation 1.8
iron deficiency anemia 1.8
pituitary adenoma 1.8
lupus 1.8
bacterial meningitis 1.7
Giant 1.7
lactic acidosis 1.7
proptosis 1.7
pneumonia 1.7
scoliosis 1.7
encephalomyelitis 1.6
ileus 1.6
Hashimoto's thyroiditis 1.6
chronic liver disease 1.6
lupus 1.6
myositis 1.6
typhoid 1.6
chronic disease 1.6
neuroblastoma 1.5
fibromyalgia 1.5
hemangioma 1.5
Disorder 1.5
HCG 1.5
retinopathy 1.5
antiphospholipid syndrome 1.5
mania 1.5
edentulous 1.5
bowel obstruction 1.4
metabolic disorder 1.4
panic disorder 1.4
vasculitis 1.4
respiratory infection 1.4
stroke 1.4
diabetic nephropathy 1.3
Posterior 1.3
systemic lupus erythematosus 1.3
B-cell lymphoma 1.3
suicide 1.3
arteriosclerosis 1.3
cerebral ischemia 1.3
subarachnoid hemorrhage 1.2
dental caries 1.2
hyperphagia 1.1
multiple sclerosis 1.1
aggressiveness 1.1
autoimmune disease 1.1
psychological stress 1.1
fits 1.1
skin cancer 1.1
measles 1.1
GSH 1.1
urticaria 1.0
NOD 1.0
neuroticism 1.0
Lupus 1.0
teratoma 1.0
PCP 1.0
herpes simplex 0.9
macular degeneration 0.9
bipolar disorder 0.9
status epilepticus 0.9
malabsorption 0.9
diphtheria 0.9
respiratory failure 0.9
anxiety disorders 0.8
Duchenne muscular dystrophy 0.8
mental retardation 0.8
wasting 0.8
Anterior 0.7
blindness 0.7
Cryptococcus neoformans 0.7
psychological distress 0.7
worms 0.7
arthropathy 0.7
migraine 0.7
syphilis 0.7
periodontal disease 0.7
systemic disease 0.7
Best 0.6
hyperparathyroidism 0.6
Graves' disease 0.6
genetic disorder 0.6
Blocking 0.6
strabismus 0.5
malnutrition 0.5
chronic pain 0.5
ventricular fibrillation 0.4
DBA 0.4
immunodeficiency 0.4
anemia 0.4
meningitis 0.4
acute pancreatitis 0.4
Syndrome 0.3
plaque 0.3
PSS 0.3
respiratory disease 0.3
ventricular hypertrophy 0.3
gastroenteritis 0.2
congestive heart failure 0.2
virus infection 0.2
Evans 0.2
deep vein thrombosis 0.1
ATM 0.1
ischemia 0.1
Poland 0.1
celiac disease 0.0
NAME 0.0
substance abuse 0.0
myelopathy -0.0
cirrhosis -0.1
Down syndrome -0.1
cataract -0.1
pheochromocytoma -0.1
Mycoplasma -0.1
dengue -0.1
pulmonary embolism -0.1
hypercholesterolemia -0.2
abortion -0.2
bacterial infection -0.2
endocarditis -0.2
mental retardation -0.2
hypothyroidism -0.3
lung disease -0.3
cardiovascular disease -0.3
rash -0.3
hypertension -0.3
melanoma -0.4
mole -0.4
alcoholism -0.4
cold -0.4
chronic hepatitis -0.6
primary tumor -0.6
infectious diseases -0.6
adenoma -0.6
diabetes -0.7
TEM -0.7
myocardial infarction -0.7
cervical cancer -0.7
renal cell carcinoma -0.7
renal disease -0.7
SEM -0.8
dehydration -0.8
sarcoma -0.9
rheumatoid arthritis -1.0
addiction -1.1
HIV -1.1
cytomegalovirus -1.1
type 2 diabetes -1.1
thrombocytopenia -1.2
glioma -1.2
liver disease -1.2
renal failure -1.2
autism -1.3
hepatitis C -1.3
heart disease -1.3
gastric cancer -1.4
West -1.4
Infection -1.5
coronary artery disease -1.7
leukemia -1.8
sepsis -2.0
influenza -2.1
sepsis -2.1
AIDS -2.2
obesity -2.2
adenocarcinoma -2.3
tumor -2.3
arthritis -2.4
lung cancer -2.4
heart failure -2.4
lymphoma -2.4
asthma -2.6
metastases -2.9
carcinoma -3.5
cancer -4.3
Symptom
Cog-wheel rigidity 13.7
bradykinesia 13.7
Fine tremor 12.7
Freezing phenomenon 12.7
Marked rigidity 12.1
Extrapyramidal rigidity 12.1
Rest tremor 11.6
impaired body balance 11.4
Antecollis 10.9
Parkinsonian rest tremor 10.7
motor symptom 10.4
muscle rigidity 10.2
tremor 9.8
Postural tremor 9.6
waxy flexibility 9.5
Extrapyramidal symptoms 9.4
abnormal gait 8.4
chorea 8.4
hemihypesthesia 8.1
dystonia 8.1
abnormal reflex 7.9
dysarthria 7.9
Decreased activity 7.7
Involuntary Movement 7.6
Kayser-Fleischer ring 7.5
clumsiness 7.4
Behavioral symptoms 7.4
Motor dysfunction 7.4
Parkinsonian tremor 7.3
athetosis 7.3
Fear of falling 7.2
Fear of falling 7.2
asterixis 7.0
myoclonus 6.9
ataxic gait 6.9
drooling 6.9
blepharospasm 6.7
excessive sweating 6.6
apathy 6.5
catatonia 6.4
cerebellar ataxia 6.4
intention tremor 6.3
hypertonia 6.2
arm weakness 6.2
personality change 6.2
adipsia 6.2
Lower urinary tract symptoms 6.2
aphagia 6.1
forgetfulness 5.9
disturbed balance 5.9
ataxia 5.9
aphonia 5.8
incoordination 5.7
ophthalmoplegia 5.7
memory loss 5.7
auditory hallucination 5.7
spasticity 5.7
consciousness disturbance 5.6
lassitude 5.6
visual hallucination 5.6
muscle stiffness 5.5
thirsty 5.4
Psychiatric symptoms 5.4
constipation 5.3
eds 5.3
prostration 5.2
anosmia 5.1
paraparesis 5.1
torticollis 5.1
pallor 5.0
fasciculation 5.0
muscle cramps 4.9
sleepiness 4.8
insomnia 4.7
retching 4.6
urinary frequency 4.6
Fluctuation 4.5
tonic-clonic seizure 4.4
Sedation 4.3
partial seizure 4.3
stridor 4.1
dysuria 4.0
paresis 4.0
neurological disability 3.9
dysesthesia 3.8
orofacial pain 3.8
agitation 3.8
hypersomnia 3.7
weakness 3.6
decreased appetite 3.5
dizziness 3.5
paresthesia 3.5
tingling 3.4
asthenia 3.4
nasal discharge 3.3
nausea 3.3
lethargy 3.2
bloating 3.0
oliguria 2.9
hypotonia 2.8
Depressive symptoms 2.8
hemiplegia 2.8
leg pain 2.7
twitching 2.7
fatigue 2.7
blurred vision 2.7
skin irritation 2.7
myalgia 2.6
functional recovery 2.6
vertigo 2.5
seizures 2.4
tachypnea 2.4
numbness 2.4
knee pain 2.3
cachexia 2.3
snoring 2.2
vomiting 2.2
nausea and vomiting 2.1
epigastric pain 2.0
anorexia 2.0
hypothermia 2.0
spasm 1.9
thinning 1.9
cyanosis 1.8
neck pain 1.8
discomfort 1.6
syncope 1.5
dyspnea 1.5
headache 1.5
wheezing 1.5
discomfort 1.5
low back pain 1.4
shortness of breath 1.4
back pain 1.2
exhaustion 1.0
pain 1.0
distraction 0.5
respiratory distress 0.5
Ill 0.3
cough 0.2
stigma 0.0
anesthesia -0.2
analgesia -1.1
collapse -1.1
diarrhea -1.1
abdominal pain -1.2
Drug
Tandospirone citrate 12.1
Flunarizine hydrochloride 11.7
Dophamine 11.1
Succinobucol 10.7
Bupleurum root 10.6
Lergotrile mesylate 10.6
Mirapex 10.3
Lergotrile 10.2
Blonanserin 10.0
Sinemet 9.9
Sinemet 9.7
Droxidopa 9.2
Benserazide 9.0
Istradefylline 9.0
Madopar 8.9
Sinemet 8.8
Topamax 8.8
Eldepryl 8.8
Metoclopramide hydrochloride 8.7
Eldepryl 8.6
Azilect 8.4
DBS 8.3
Lisuride 8.2
Parlodel 8.1
Rasagiline 8.0
Tianma 8.0
Carbidopa 8.0
Parlodel 8.0
Primperan 7.7
3,4-Dihydroxyphenylalanine 7.4
Rosin 7.2
Sodium benzoate 7.1
Safflower 6.8
MDS 6.6
Moclobemide 6.2
Pramipexole 6.0
Apomorphine 6.0
Pramipexole 6.0
Parkin 5.7
Parkin 5.7
CFT 5.5
Donepezil 4.6
Frontal 4.3
Tocopherol 4.3
Posture 4.1
Bupivacaine 4.1
Android 4.1
NVP 3.8
Reserpine 3.8
DM1 3.1
Triclosan 3.1
Diurnal 3.0
niacin 2.8
Portal 2.7
uPA 2.7
Dakar 2.7
TMS 2.5
pyridoxal phosphate 2.4
CSF 2.4
HCG 2.3
ICI 2.3
PCP 1.9
caffeine 1.3
CTX 1.3
CTX 1.2
vitamin E 1.2
ascorbate 0.8
ROC 0.8
Spectrum 0.8
ENT 0.7
ROS 0.5
citric acid 0.5
CTX 0.4
MAP -0.2
NADH -0.7
Monit -1.4
Enzyme
pantothenate kinase 7.8
nicotinamide N-methyltransferase 7.2
catechol O-methyltransferase 6.7
GD3 synthase 6.2
MPP 6.0
DAT 6.0
tyrosine hydroxylase 5.9
DOPA decarboxylase 5.3
monoamine oxidase 5.1
cyclohydrolase 5.0
CNPase 4.7
isopeptidase 4.6
myrosinase 4.6
aldehyde oxidase 4.2
FAST 4.2
GABA transaminase 4.1
ceruloplasmin 4.0
Thy1 3.5
heme oxygenase 3.3
glucocerebrosidase 3.2
complex I 3.2
Alternating 3.1
PAL 3.1
paraoxonase 3.0
MEKK1 2.9
paraoxonase 2.7
caspase-3 2.7
cholinesterase 2.7
PAL 2.7
phosphoglycerate kinase 2.6
caspase-9 2.4
PKG 2.4
acetylcholinesterase 2.3
proteasome 2.2
AMPK 2.1
choline acetyltransferase 2.1
granzyme B 2.0
GSK 2.0
hexosaminidase 1.9
PDE 1.9
PCP 1.8
proteinase K 1.7
cathepsin B 1.7
transglutaminase 1.5
aldehyde dehydrogenase 1.4
AMPK 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
AMP-activated protein kinase 1.1
superoxide dismutase 1.1
papain 1.0
NOS 0.9
beta-galactosidase 0.9
glutathione peroxidase 0.9
MAP 0.9
succinate dehydrogenase 0.7
guanylate cyclase 0.7
phosphodiesterase 0.5
glutathione reductase 0.5
CD10 0.5
NADPH oxidase 0.4
urokinase-type plasminogen activator 0.3
phosphatidylinositol 3-kinase 0.3
catalase 0.3
ACS 0.3
NADPH oxidase 0.3
tissue plasminogen activator 0.3
protein kinase 0.2
ATPase 0.1
P-glycoprotein 0.0
PARP -0.0
mitogen-activated protein kinase -0.2
calcineurin -0.3
MEK -0.4
creatine kinase -0.5
ERK -0.5
protein kinase C -0.9
lactate dehydrogenase -1.1
peroxidase -1.3
Compound
tris(2-chloropropyl) phosphate 10.9
1-benzyl-1,2,3,4-tetrahydroisoquinoline 9.7
nicotinaldehyde 9.3
nicotinaldehyde 9.3
nicotinaldehyde 9.3
nicotinaldehyde 9.3
4-phenyl-1,2,3,6-tetrahydropyridine 9.2
nicotinaldehyde 9.2
nicotinaldehyde 9.2
nicotinaldehyde 9.1
nicotinaldehyde 9.1
nicotinaldehyde 9.0
nicotinaldehyde 9.0
Ropinirole 9.0
1,3-dihydro-2H-benzimidazol-2-one 8.7
Monoolein 8.7
nicotinaldehyde 8.6
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8.5
MPTP 8.5
Metoclopramide hydrochloride 8.4
DBS 8.3
Biopterin 8.2
Pergolide 8.0
PDQ 8.0
L-DOPA 7.9
DCI 7.9
Biperiden 7.9
HFr 7.9
Loganin 7.7
PAPP 7.6
Selegiline 7.6
PAPP 7.4
Deguelin 7.4
PSP 7.4
1-Methyl-4-phenylpyridinium 7.2
CIT 7.2
CIT 7.1
Isatin 7.1
Amantadine 7.1
Amantadine 7.1
hydroxytyramine 7.0
Amantadine 7.0
Bromocriptine 7.0
TLA 7.0
Dopa 6.7
Amantadine 6.7
cyclohexanecarboxylic acid 6.5
cyclohexanecarboxylic acid 6.5
cyclohexanecarboxylic acid 6.5
cyclohexanecarboxylic acid 6.5
cyclohexanecarboxylic acid 6.5
Geniposide 6.4
Rotenone 6.4
Anthraquinone 6.3
MPP 6.1
NOP 6.1
MPP 6.1
1,2,3,4-tetrahydroisoquinoline 6.1
tris(2-chloroethyl) phosphate 6.1
DAT 6.0
Dopamine 6.0
3,4-dihydroxyphenylalanine 6.0
Cabergoline 5.8
Quetiapine 5.8
MPE 5.7
Ethylene oxide 5.7
Pantothenate 5.7
Paeoniflorin 5.5
Thiabendazole 5.4
MHPG 5.4
Alba 5.4
TDT 5.4
Tannin 5.3
Haloperidol 5.2
Carvacrol 5.2
MCE 5.1
Methysergide 5.1
THIP 5.1
Haloperidol 5.1
Riluzole 5.1
Methylphenidate 5.0
DDC 5.0
DDC 5.0
Olanzapine 4.9
Citalopram 4.9
Cannabidiol 4.8
PDP 4.8
Crystal Violet 4.8
BDS 4.8
TDP 4.8
NFS 4.7
CAA 4.7
methylformamide 4.7
HVA 4.6
Coronal 4.5
galanthamine 4.3
Tramadol 4.3
TAR 4.3
Metoclopramide 4.2
5-HIAA 4.2
Bupivacaine 4.2
coenzyme Q10 4.1
Muscimol 4.1
Docosahexaenoic acid 4.0
DDC 3.9
DOPAC 3.9
Pima 3.9
Neuronal 3.8
Minocycline 3.8
Valproic acid 3.7
neopterin 3.7
IMP 3.7
Epigallocatechin gallate 3.7
A 71 3.6
Dipyridamole 3.6
Dipyridamole 3.6
Dipyridamole 3.6
Dipyridamole 3.6
DMD 3.6
Coenzyme Q10 3.5
Berberine 3.5
FTA 3.5
dipropyl 3.4
Ribavirin 3.4
MK801 3.4
Catechol 3.4
Ubiquitin 3.4
manganese 3.3
Formal 3.3
4-chlorophenyl 3.3
4-chlorophenyl 3.3
TMA 3.2
TMA 3.2
Catechol 3.1
5-hydroxytryptophan 3.1
PLP 3.0
TAP 3.0
GABA 3.0
GABA 3.0
Clozapine 3.0
Valproic acid 3.0
GM2 3.0
Morphine 3.0
Flux 3.0
LPC 2.9
cyclopentyl 2.9
hydroxyindoleacetic acid 2.8
MCP 2.8
5-HT 2.8
Piper 2.7
Reserpine 2.7
Resveratrol 2.6
His 2.6
gamma-aminobutyric acid 2.6
NMDA 2.6
Nicotine 2.5
Letter 2.5
glutamate 2.5
SEE 2.4
noradrenaline 2.4
chalcone 2.4
isoxazole 2.4
Neu5Ac 2.4
Theophylline 2.3
Adenine 2.3
isoquinoline 2.2
octane 2.2
ACM 2.2
benzamide 2.1
GM1 2.1
Guo 2.1
A 1 2.1
PAP 2.1
PAP 2.1
Glutamate 2.1
ICI 2.1
N-acetylaspartate 2.1
Neo 2.0
Adenosine 2.0
BRL 1.9
tungsten 1.9
CBS 1.9
L-carnitine 1.8
Tyrosine 1.8
THE 1.7
benzaldehyde 1.7
Cocaine 1.7
ANA 1.6
ANA 1.6
Retard 1.6
caffeine 1.6
DSM 1.6
PCP 1.6
Lithium 1.5
Guo 1.5
Histone 1.5
valine 1.5
AMPA 1.5
phosphocreatine 1.4
Cyclosporine 1.4
aspartic acid 1.4
aspartic acid 1.4
APAP 1.3
piperazine 1.3
cyanide 1.3
gallic acid 1.2
aspartic acid 1.2
iron 1.2
TRH 1.1
aspartic acid 1.1
Curcumin 1.1
Melatonin 1.0
Isoproterenol 1.0
Off 1.0
GSH 1.0
GSH 1.0
Cereb 1.0
6-12 0.9
prostaglandin E1 0.9
GTP 0.9
H2S 0.8
A 3 0.8
dUTP 0.8
benzoic acid 0.8
MDA 0.7
H2S 0.7
glutamic acid 0.7
Adrenal 0.7
Salt 0.7
Optimal 0.6
CAT 0.6
CAT 0.6
HCl 0.6
mercury 0.6
guanidine 0.6
MAP 0.5
Estrogen 0.5
isopropanol 0.5
CAT 0.5
cAMP 0.5
iodine 0.4
Lead 0.4
Carbon 0.4
CTX 0.4
isoleucine 0.4
oxalate 0.4
Estrogen 0.4
isoleucine 0.4
cGMP 0.4
nitric oxide 0.3
Clin 0.3
ACS 0.3
ACS 0.3
homocysteine 0.2
acetic acid 0.2
potassium 0.2
COS 0.1
MEK 0.1
copper 0.0
glutamine 0.0
ethyl acetate -0.0
oxygen -0.0
Dec -0.0
ATP -0.1
silver -0.1
CoA -0.2
chlorine -0.3
MTT -0.3
barium -0.3
nicotinamide -0.3
acrylamide -0.3
fluorine -0.4
Asp -0.4
boron -0.4
vinyl -0.4
galactose -0.5
cysteine -0.5
tyrosine -0.5
PEG -0.5
calcium -0.5
methionine -0.5
creatinine -0.5
methanol -0.6
NAD -0.6
Ile -0.6
NADH -0.7
serine -0.7
glucose -0.8
alanine -0.8
Phe -0.9
NAD -1.0
phenol -1.0
pyridine -1.0
sulfate -1.1
PEG -1.1
ethanol -1.1
aluminum -1.1
carbonate -1.1
CO2 -1.2
leucine -1.2
H2O2 -1.2
proline -1.2
arginine -1.2
tryptophan -1.4
tryptophan -1.4
tryptophan -1.4
water -1.4
tryptophan -1.6
AMP -1.6
bromide -1.7
silicon -1.7
ammonia -1.7
DNA -1.8
NH2 -1.8
nitrogen -2.0
sodium -2.0
acetate -2.1
TNF -2.2
hydrogen -2.9
phosphate -3.7