Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0233565 (bradykinesia)
 2,352 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
KIAA1024L 13.7
BBG-TCC 12.7
USP31 10.7
ATP1B4 10.7
phosphodiesterase 8B 10.4
SNCAIP 9.7
ANO10 9.6
CHD6 9.6
STX6 9.5
NMD3 9.4
Kufor-Rakeb syndrome 9.2
IRX2 9.1
PANK2 9.1
HNMT 9.0
Synaptojanin 1 9.0
calmodulin-like skin protein 8.9
with Parkinsonism 8.8
CHCHD2 8.8
CIT 8.7
ATP13A2 8.7
PKAN 8.7
Alpha synuclein 8.7
F-box only protein 7 8.7
PARK8 8.7
vacuolar protein sorting 35 8.7
STN 8.6
SCA8 8.6
Hallervorden-Spatz syndrome 8.6
USP30 8.5
KCNJ6 8.5
SCA17 8.5
EIF4G1 8.4
STK39 8.4
DYT11 8.4
DBS 8.3
LRRK2 8.3
MOBP 8.2
PRKACB 8.2
Dopamine transporter 8.1
SV2C 8.1
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Disease
early parkinson's 13.7
Pallidonigral degeneration 13.7
Bradyphrenia 13.1
Supranuclear gaze palsy 12.7
SCAR6 12.1
CRCL 12.1
Secondary parkinsonism 11.9
Vascular parkinsonism 11.7
PARK12 11.4
Striatonigral degeneration 11.3
SCA21 11.1
Vertical gaze palsy 10.7
PARK3 10.6
hemiparkinsonism 10.3
organic delusional syndrome 10.3
Ideational apraxia 10.3
CNS degenerative disease 10.3
Juvenile Parkinsonism 10.3
Parkinson's disease and parkinsonism 10.0
organic personality syndrome 10.0
mild memory disturbance 10.0
akinesia 10.0
Ideomotor apraxia 9.8
Corticobasal degeneration 9.6
Cerebellar degeneration 9.3
REM sleep behavior disorder 9.1
camptocormia 9.0
PARK8 9.0
parkinsonism 8.9
dysbasia 8.9
Progressive dementia 8.9
pseudobulbar palsy 8.9
dyskinesia 8.8
anarthria 8.6
extrapyramidal disorder 8.6
movement disorder 8.5
Parkinson's disease 8.5
DYT11 8.5
progressive supranuclear palsy 8.5
SCA17 8.4
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Symptom
Cog-wheel rigidity 13.7
bradykinesia 13.7
Freezing phenomenon 12.7
Fine tremor 12.7
Extrapyramidal rigidity 12.1
Marked rigidity 12.1
Rest tremor 11.6
impaired body balance 11.4
Antecollis 10.9
Parkinsonian rest tremor 10.7
motor symptom 10.4
muscle rigidity 10.2
tremor 9.8
Postural tremor 9.6
waxy flexibility 9.5
Extrapyramidal symptoms 9.4
abnormal gait 8.4
chorea 8.4
hemihypesthesia 8.1
dystonia 8.1
abnormal reflex 7.9
dysarthria 7.9
Decreased activity 7.7
Involuntary Movement 7.6
Kayser-Fleischer ring 7.5
clumsiness 7.4
Behavioral symptoms 7.4
Motor dysfunction 7.4
Parkinsonian tremor 7.3
athetosis 7.3
Fear of falling 7.2
Fear of falling 7.2
asterixis 7.0
myoclonus 6.9
ataxic gait 6.9
drooling 6.9
blepharospasm 6.7
excessive sweating 6.6
apathy 6.5
catatonia 6.4
more...
Drug
Tandospirone citrate 12.1
Flunarizine hydrochloride 11.7
Dophamine 11.1
Succinobucol 10.7
Lergotrile mesylate 10.6
Bupleurum root 10.6
Mirapex 10.3
Lergotrile 10.2
Blonanserin 10.0
Sinemet 9.9
Sinemet 9.7
Droxidopa 9.2
Istradefylline 9.0
Benserazide 9.0
Madopar 8.9
Sinemet 8.8
Topamax 8.8
Eldepryl 8.8
Metoclopramide hydrochloride 8.7
Eldepryl 8.6
Azilect 8.4
DBS 8.3
Lisuride 8.2
Parlodel 8.1
Rasagiline 8.0
Tianma 8.0
Carbidopa 8.0
Parlodel 8.0
Primperan 7.7
3,4-Dihydroxyphenylalanine 7.4
Rosin 7.2
Sodium benzoate 7.1
Safflower 6.8
MDS 6.6
Moclobemide 6.2
Pramipexole 6.0
Apomorphine 6.0
Pramipexole 6.0
Parkin 5.7
Parkin 5.7
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Enzyme
pantothenate kinase 7.8
nicotinamide N-methyltransferase 7.2
catechol O-methyltransferase 6.7
GD3 synthase 6.2
MPP 6.0
DAT 6.0
tyrosine hydroxylase 5.9
DOPA decarboxylase 5.3
monoamine oxidase 5.1
cyclohydrolase 5.0
CNPase 4.7
isopeptidase 4.6
myrosinase 4.6
aldehyde oxidase 4.2
FAST 4.2
GABA transaminase 4.1
ceruloplasmin 4.0
Thy1 3.5
heme oxygenase 3.3
glucocerebrosidase 3.2
complex I 3.2
Alternating 3.1
PAL 3.1
paraoxonase 3.0
MEKK1 2.9
paraoxonase 2.7
caspase-3 2.7
cholinesterase 2.7
PAL 2.7
phosphoglycerate kinase 2.6
caspase-9 2.4
PKG 2.4
acetylcholinesterase 2.3
proteasome 2.2
AMPK 2.1
choline acetyltransferase 2.1
granzyme B 2.0
GSK 2.0
hexosaminidase 1.9
PDE 1.9
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Compound
tris(2-chloropropyl) phosphate 10.9
1-benzyl-1,2,3,4-tetrahydroisoquinoline 9.7
nicotinaldehyde 9.3
nicotinaldehyde 9.3
nicotinaldehyde 9.3
nicotinaldehyde 9.3
4-phenyl-1,2,3,6-tetrahydropyridine 9.2
nicotinaldehyde 9.2
nicotinaldehyde 9.2
nicotinaldehyde 9.1
nicotinaldehyde 9.1
nicotinaldehyde 9.0
nicotinaldehyde 9.0
Ropinirole 9.0
1,3-dihydro-2H-benzimidazol-2-one 8.7
Monoolein 8.7
nicotinaldehyde 8.6
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 8.5
MPTP 8.5
Metoclopramide hydrochloride 8.4
DBS 8.3
Biopterin 8.2
Pergolide 8.0
PDQ 8.0
L-DOPA 7.9
DCI 7.9
Biperiden 7.9
HFr 7.9
Loganin 7.7
PAPP 7.6
Selegiline 7.6
PAPP 7.4
Deguelin 7.4
PSP 7.4
1-Methyl-4-phenylpyridinium 7.2
CIT 7.2
CIT 7.1
Isatin 7.1
Amantadine 7.1
Amantadine 7.1
more...