Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0233565 (bradykinesia)
 2,352 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 149
MRI 116
tyrosine hydroxylase 64
synuclein 52
She 51
Mol 46
alpha-synuclein 39
dopamine transporter 35
olfactory 32
CIT 29
LRRK2 22
Pol 22
asymmetrical 21
DBS 21
GABA 21
ubiquitin 20
STN 20
axonal 19
MAO-B 17
caspase-3 17
more...
Disease
Parkinson's disease 1684
parkinsonism 526
dementia 226
akinesia 175
dyskinesia 174
depression 166
movement disorder 122
cognitive impairment 122
Alzheimer's disease 106
progressive supranuclear palsy 89
Huntington's disease 76
psychosis 65
hallucinations 48
apraxia 43
dysphagia 38
sleep disorders 31
sleep disturbances 30
stroke 28
catalepsy 27
Dementia with Lewy bodies 24
more...
Symptom
bradykinesia 2352
tremor 1251
dystonia 167
muscle rigidity 93
ataxia 69
dysarthria 67
chorea 51
motor symptom 47
myoclonus 39
pain 38
weakness 33
seizures 32
constipation 29
apathy 28
abnormal gait 28
sleepiness 27
fatigue 25
spasticity 24
cerebellar ataxia 22
insomnia 20
more...
Drug
DBS 21
Sinemet 18
MDS 16
Sinemet 15
Sinemet 15
CSF 12
Parkin 7
Posture 7
Parkin 7
Apomorphine 6
caffeine 4
Parlodel 4
Madopar 4
vitamin E 3
Parlodel 3
ascorbate 3
Rasagiline 3
Carbidopa 3
Frontal 3
Lisuride 3
more...
Enzyme
tyrosine hydroxylase 63
monoamine oxidase 28
caspase-3 17
acetylcholinesterase 10
proteasome 10
superoxide dismutase 9
MPP 9
DAT 7
protein kinase 7
ACS 7
cholinesterase 6
ceruloplasmin 6
complex I 6
mitogen-activated protein kinase 6
ATPase 5
ERK 5
catalase 5
pantothenate kinase 4
DOPA decarboxylase 3
caspase-9 3
more...
Compound
L-DOPA 161
Dec 153
Clin 140
MPTP 135
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 86
Dopamine 41
His 35
glutamate 31
CIT 29
CIT 29
oxygen 27
manganese 26
iron 23
DBS 21
GABA 21
GABA 21
water 19
DNA 18
calcium 17
5-HT 16
more...