Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0232605 (regurgitation)
 8,217 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

One hundred and fifty-three patients undergoing De Vega tricuspid annuloplasty, with or without other associated cardiac procedures between January, 1979, and June, 1987, were evaluated. There were 136 hospital survivors. The follow-up was 98.1% complete for a mean of 3.7 years/patient. Operative mortality was 11.1%; preoperative NYHA class and length of CPB were significant risk factors of perioperative mortality. The actuarial survival of operative survivors at 9 years was 73.5 +/- 11.8%. There were 7 late cardiac deaths among a total of 12 late deaths. Eleven patients required reoperation (2.1 +/- 0.6% patient-year). In seven patients it was necessary for recurrence of tricuspid regurgitation; six of these had also a mitral prosthesis malfunction or a periprosthetic leak. Residual tricuspid regurgitation was judged as mild, moderate or severe in 29.9%, 11.9% and 4.3% of the patients respectively. De Vega tricuspid annuloplasty is the method of choice for mild and moderate tricuspid insufficiency; in selected cases, with a more severe degree of regurgitation, better results could be achieved with a different surgical approach.
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PMID:The De Vega tricuspid annuloplasty. Perioperative mortality and long term follow-up. 221 7

27 cases of partial atrioventricular canal malformations were treated surgically, without operative death or serious complications. There were 15 males and 12 females, aged from 6 to 32 years (mean 14.7 years). Diagnosis was confirmed by echocardiography in all cases and catheterization in 13 as well. Surgical correction was performed under CPB combined with moderate hypothermia. Right atrium approach was used. The anterior mitral cleft was sewn with interrupted sutures and annuloplasty is done when regurgitation is obvious. Atrial septal defect was repaired with patch.
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PMID:[Surgical treatment of partial atrioventricular canal malformations]. 237 28

During the past 7 1/2 years, 36 infants (less than or equal to 6 months of age) underwent surgical relief of critical pulmonary valve stenosis. The results of closed and open (cardiopulmonary bypass, CPB) procedures were compared. Closed procedures included Brock valvotomy (two patients) and normothermic inflow stasis with transpulmonary valvectomy (10 patients). Twenty-two patients had open procedures with valvectomy alone (five patients) and right ventricular outflow tract (RVOT) reconstruction (17 patients). Two additional patients had staged operations (shunt followed by open procedure at 3 and 5 months postoperatively). Patients who had the closed procedures, as compared with CPB, were significantly younger (10 versus 61 days, p less than 0.01) and more critically ill with congestive heart failure and acidosis. In addition, the mean peak systolic right ventricular-left ventricular pressure ratios (RVP/LVP) were higher (1.6 versus 1.4, p less than 0.02) in the closed group. There were no deaths in the closed group in contrast to six deaths among those having RVOT reconstruction (0/12 versus 6/17 or 35%, p less than 0.04). Critical obstruction of the pulmonary valve, tricuspid valve regurgitation, and hypoplastia of the right ventricle occurred more frequently in the closed group. All operative deaths resulted from right heart failure. There were no late deaths in the entire series. Three patients in the closed group (mean follow-up 2.8 years) required operations for recurrent pulmonary valve stenosis approximately 2 years postoperatively, and none in the open group (mean follow-up 2.0 years). In conclusion, despite current advances in infant CPB and care, the results from our experience suggests that closed procedures, especially inflow stasis and pulmonary valvectomy, are superior to the use of CPB and RVOT reconstruction, even in the presence of pulmonary valve dysplasia.
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PMID:Surgical approach to critical pulmonary valve stenosis in infants less than six months of age. 682 45

For a period of 13 months (from April 1993 till May 1994) 14 patients (5 men and 9 women) have been examined intraoperatively with transesophageal echocardiography. Nine of the patients were with mitral valve lesion, three of them with mitral valve lesion, complicated with tricuspidalisation, one patient with mitral-aortic valve lesion and high grade tricuspid regurgitation and one patient with aortic valve disease. The purpose of the intraoperative transesophageal echocardiography was to surgical valve repair by measuring the residual stenosis and regurgitation. Intraoperative transesophageal echocardiography evaluation was made by biplane two-dimensional echocardiography, colour Doppler mapping and pulse wave Doppler after CPB before sternum closure. In 13 of the examined patients the effect of the surgical valve repair was assessed by transesophageal echocardiography as very good. In one of the cases intraoperative transesophageal echocardiography indicated aortic and mitral valve replacement because of high grade aortic and mitral replacement, persisting after surgical valve repair of both valves. Intraoperative transesophageal echocardiographic findings were compared with postoperative transesophageal echocardiography before dehospitalisation of the patients. The results of both echocardiographic examinations, correlate to a great extent. The existing difference in assessment of the degree of valvular lesions is due to the specific intraoperative haemodynamic situation. Intraoperative transesophageal echocardiography is a valuable method in assessment of surgical valve repair.
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PMID:[Intraoperative transesophageal echocardiography in patients with surgical valve repair]. 747 61