Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0232487 (abdominal discomfort)
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Human Gene/Protein
CLC2 10.7
RPEL 9.8
Wes 9.6
BGR 9.5
SSR2 9.5
Apolipoprotein A-II 9.1
SYT-SSX2 8.7
BUP 8.5
SYT-SSX1 8.5
HELIOS 8.0
neutrophil protein 8.0
PRY 7.9
CA-125 7.2
CNA 6.9
KIT protein 6.9
SS18 6.8
helicase II 6.7
SLL 6.7
SWAP 6.5
CD51 6.5
ASS 6.4
CD35 6.3
CPI-17 6.3
BRI 6.3
5-HT4 6.3
SASP 6.1
MB2 6.1
DAXX 6.1
CD99 6.0
MB1 6.0
LCP 5.9
chitotriosidase 5.8
HIP 5.8
HNPCC 5.8
transcobalamin II 5.7
IDA 5.6
alpha-1-antichymotrypsin 5.6
chromogranin A 5.6
ClC-2 5.6
Melan-A 5.6
PDL1 5.6
rohu 5.5
HAI 5.5
TACE 5.5
IRIS 5.5
maspin 5.5
GIT 5.5
CD117 5.5
CD21 5.5
CK7 5.5
lactase 5.5
ACG 5.4
TPH 5.4
ankyrin 1 5.4
BCM 5.4
TIA-1 5.4
follicle-stimulating hormone receptor 5.4
ROCK2 5.3
EPH 5.3
Synaptophysin 5.3
SMS 5.3
Kv1.4 5.3
SS1 5.3
She 5.2
MYPT1 5.2
GIST 5.2
Ki-1 5.2
HUS 5.2
homeobox transcription factor 5.2
DQ2 5.2
pT3 5.2
TMEM16A 5.1
Musashi-1 5.1
AE3 5.1
white cell 5.1
MTX 5.1
thyroid transcription factor-1 5.1
intrinsic factor 5.0
GTT 5.0
fruitless 5.0
more...
Disease
anemia; progressive 14.2
Cyclic edema 14.2
Xiphodynia 14.2
Dientamoebiasis 12.6
iridocyclochoroiditis 12.6
stage IV cervical cancer 12.6
Larva currens 12.6
Cholangiohepatitis 12.6
Adult hypertrophic pyloric stenosis 12.6
Retroperitoneal sarcoma 12.0
Pyeloduodenal fistula 11.9
Dientamoeba fragilis infection 11.9
Diphyllobothrium latum infection 11.7
Celiac artery aneurysm 11.4
nanophyetiasis 11.4
mesothelial neoplasm 11.2
toxic amblyopia 11.2
vaginal neoplasm 11.2
Colonic lipoma 11.2
Anemia in chronic kidney disease 11.0
Gastrocolic fistula 10.9
Esophageal leiomyoma 10.7
Hypervitaminosis D 10.5
postvagotomy syndrome 10.5
Adenoviral infections 10.3
Diversion colitis 10.1
Gastrointestinal lymphoma 10.1
Carotenemia 10.1
Mesenteric fibromatosis 10.0
Sigmoid colon 10.0
Sigmoid colon 10.0
Unconjugated hyperbilirubinemia 9.9
necatoriasis 9.9
environmental allergy 9.9
Chronic idiopathic constipation 9.7
Cellular angiofibroma 9.6
mesenteric vascular insufficiency 9.6
Sclerosing mesenteritis 9.5
abdominal obstruction 9.4
Granulomatous hepatitis 9.3
Abdominal actinomycosis 9.3
Ehrlichia canis infection 9.3
sea sickness 9.3
myxolipoma 9.2
Gastric dilatation 9.2
vitamin B12 deficiency anemia 9.2
lymphangiomyoma 9.2
Biliary cystadenoma 9.2
Emphysematous gastritis 9.2
aerophagia 9.1
Eosinophilic myocarditis 9.0
balantidiasis 9.0
Ruptured abdominal aortic aneurysm 9.0
Mucinous cystadenoma 9.0
Meigs' syndrome 9.0
Gastric carcinoid 9.0
diphyllobothriasis 9.0
Appendiceal mucocele 9.0
Myelolipoma 8.9
metagonimiasis 8.9
Sclerosing peritonitis 8.9
Emphysematous cholecystitis 8.9
Pneumatosis cystoides intestinalis 8.8
Brunner's gland hyperplasia 8.8
recurrent pancreatic cancer 8.8
Ectopic pancreas 8.7
Diabetic gastroparesis 8.7
Cholestatic liver disease 8.7
Emphysematous cystitis 8.7
Sandifer syndrome 8.6
Littoral cell angioma 8.6
Functional dyspepsia 8.6
sinobronchial syndrome 8.6
Mayer-Rokitansky-Kuster-Hauser syndrome 8.6
Erosive gastritis 8.6
cryptitis 8.6
Intrahepatic cholestasis 8.5
pharyngolaryngitis 8.5
Solid pseudopapillary tumor 8.5
FBD 8.4
more...
Symptom
abdominal discomfort 14.2
gas pain 13.2
change in bowel movements 12.4
Rovsing's sign 12.2
radiating back pain 11.2
Hemorrhagic ascites 11.2
bloating 9.7
Intermenstrual bleeding 9.2
Premenstrual symptoms 9.1
change in stool 8.9
Visceral pain 8.9
lassitude 8.8
belching 8.8
epigastric distress 8.6
Pain symptoms 8.4
Severe diarrhea 8.4
Infantile colic 8.3
Functional constipation 8.3
hematocolpos 8.2
Wind 8.1
painful swallowing 8.1
giddiness 8.1
giddiness 8.1
abdominal fullness 8.1
tenesmus 7.9
dark urine 7.6
generalized abdominal pain 7.6
sighing 7.6
chronic constipation 7.3
nausea 7.3
constipation 7.2
left upper quadrant pain 7.1
night sweats 7.1
pneumaturia 7.0
urinary frequency 7.0
heartburn 7.0
epigastric pain 7.0
frequent urination 6.8
lightheadedness 6.8
Flare 6.7
Spastic 6.7
colic 6.6
Tenderness 6.6
hypoproteinemia 6.6
rectal pain 6.6
acute abdomen 6.6
Gastrointestinal symptoms 6.6
abdominal pain 6.6
decreased appetite 6.6
chyluria 6.6
generalized pain 6.6
vomiting 6.5
anorexia 6.4
Cushingoid 6.4
dyschezia 6.4
dysuria 6.4
inanition 6.4
Cushingoid 6.4
diarrhea 6.3
hepatomegaly 6.3
anal pain 6.3
splenomegaly 6.1
rigors 6.1
retching 6.1
acute abdominal pain 6.0
excessive sweating 6.0
hyperemesis 5.9
muscle cramps 5.9
dizziness 5.9
oliguria 5.9
flank pain 5.9
thirsty 5.8
Physical findings 5.8
meningism 5.8
leg edema 5.8
nausea and vomiting 5.6
prostration 5.6
irregular bleeding 5.6
hepatosplenomegaly 5.5
discomfort 5.3
more...
Drug
Thiaton 13.2
Fennel oil 11.6
Comtan 11.4
Calcium polycarbophil 11.2
Cilansetron 10.9
Ecabet sodium 10.7
Paromomycin sulfate 10.6
Gestrinone 10.2
Fenoprofen calcium 10.2
Tegaserod 10.1
Tegaserod 10.0
Alosetron 9.5
Renzapride 9.4
Fenoprofen 9.2
Namenda 9.0
Acemannan 9.0
Pleconaril 8.9
DOXY 8.5
Tham 8.3
Cefditoren 8.1
Vibramycin 7.9
Cefprozil 7.9
Guar gum 7.6
Ethylcellulose 7.6
Miglustat 7.5
Icodextrin 7.4
Trilostane 7.4
Lutalyse 7.2
Sulprostone 7.2
Tinidazole 7.1
Lactase 7.0
Xanthan gum 7.0
Cisapride 6.8
Deferasirox 6.6
Entecavir 6.4
Entecavir 6.4
Giardiasis 6.3
Pirfenidone 6.3
Magnevist 6.2
CDX 6.2
Norplant 6.1
Sucralfate 6.1
Sandostatin 5.9
Sandostatin 5.9
Triad 5.9
Meconium 5.8
CDX 5.7
Eculizumab 5.7
Orlistat 5.6
Ipilimumab 5.5
Iohexol 5.2
Omeprazole 5.2
Troglitazone 5.1
Levonorgestrel 5.0
Lactose 5.0
Norplant 5.0
Sulpiride 5.0
Depo-Provera 4.8
Trib 4.8
Triad 4.8
Gleevec 4.7
Lipiodol 4.5
HCG 4.4
Gastro 4.3
Photofrin 4.3
Isoniazid 4.3
Itraconazole 4.2
Luteinizing 4.1
Etoposide 4.0
AMC 4.0
Aloe 3.9
Serum albumin 3.9
Imatinib 3.9
Fluconazole 3.8
Rituximab 3.7
Prednisolone 3.6
MgSO4 3.6
Bayer 3.5
Cimetidine 3.5
Cimetidine 3.5
more...
Enzyme
SOR 6.2
TACE 5.5
lactase 5.4
sucrase-isomaltase 5.4
SOR 4.7
FAST 4.6
ascorbate oxidase 4.6
sucrase 4.5
trehalase 4.4
alpha-glucosidase 4.1
sorbitol dehydrogenase 4.1
21-hydroxylase 4.0
lecithin:cholesterol acyltransferase 3.9
transglutaminase 3.9
lipase 3.7
CD10 3.5
invertase 3.5
tryptophan hydroxylase 3.4
AST 3.2
HIV-1 protease 3.1
glucoamylase 3.1
aspartate aminotransferase 3.1
gamma-glutamyl transpeptidase 3.0
alanine aminotransferase 2.9
diamine oxidase 2.9
MDP 2.8
myosin light chain kinase 2.8
thyroid peroxidase 2.6
granzyme B 2.5
UDP-glucuronosyltransferase 2.5
thromboplastin 2.5
hexosaminidase 2.4
creatine kinase 2.3
neutrophil elastase 2.2
pepsin 2.1
alkaline phosphatase 2.1
lactate dehydrogenase 1.9
kallikrein 1.6
phosphodiesterase 1.6
focal adhesion kinase 1.6
cholinesterase 1.5
reverse transcriptase 1.5
CYP3A4 1.5
prostate-specific antigen 1.4
lipoprotein lipase 1.4
NOS 1.3
glucose-6-phosphate dehydrogenase 1.2
succinate dehydrogenase 1.2
guanylate cyclase 1.1
lipoxygenase 1.1
lysozyme 0.8
chymotrypsin 0.8
thrombin 0.7
ERK 0.6
acid phosphatase 0.5
acetylcholinesterase 0.4
APC 0.2
DNA polymerase 0.1
renin 0.0
ACE 0.0
catalase -0.0
luciferase -1.0
Compound
Alverine citrate 11.6
S 16 11.0
Lubiprostone 11.0
Polygodial 9.9
Fenoprofen 9.5
Versene 9.4
Rufloxacin 9.3
Pyrantel pamoate 9.0
Ornidazole 8.4
Miglitol 8.3
2,6-DNT 8.2
Cefprozil 8.1
Anethole 8.0
X 13 8.0
Amprenavir 7.8
DR-1 7.7
Cefixime 7.6
Combretastatin A4 7.6
Entacapone 7.5
Cefotetan 7.3
Repaglinide 7.2
AT-101 7.1
AT-101 7.1
AT-101 7.1
Salvinorin A 7.0
Praziquantel 7.0
Loperamide 6.9
Cisapride 6.8
Pyridostigmine 6.8
Fluvoxamine 6.8
Acarbose 6.7
Mesalamine 6.6
CNA 6.6
Pyrogallol 6.5
2,4-DNT 6.4
Chenodeoxycholic acid 6.4
HNS 6.4
BCM 6.3
Tegafur 6.3
Lactulose 6.2
Pamidronate 6.1
Sucralfate 6.1
Letrozole 6.0
Mycophenolate mofetil 6.0
BEP 5.9
Fluvastatin 5.8
Octreotide 5.8
Tegafur 5.7
Aztreonam 5.7
DLT 5.6
2,3-dimercaptosuccinic acid 5.6
IDA 5.6
Sumatriptan 5.5
Ritonavir 5.5
TACE 5.5
2-furaldehyde 5.5
Probucol 5.5
INT 5.5
A 42 5.5
2,3-dimercaptosuccinic acid 5.5
Tranexamic acid 5.4
Zolpidem 5.4
Ceftriaxone 5.3
Celecoxib 5.3
Leucovorin 5.3
Endosulfan 5.2
Busulfan 5.2
Alendronate 5.1
MTX 5.1
A 71 5.1
Ondansetron 5.0
folinic acid 5.0
Alendronate 5.0
Lactose 5.0
Fenofibrate 4.9
Omeprazole 4.9
Memantine 4.9
Clarithromycin 4.8
Metoclopramide 4.7
Clindamycin 4.7
more...