Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0232487 (abdominal discomfort)
 1,724 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mesosigmoidoplasty is a nonresective procedure for nongangrenous sigmoid volvulus. It aims to correct the main pathogenetic factor of this condition, the narrow but long mesosigmoid. Although it had been demonstrated by intraoperative measurements that this has indeed achieved its purpose, recurrent volvulus has been reported after the procedure. This has raised the question of whether an operation on the mesosigmoid's peritoneal cover alone is sufficient to maintain the change in shape. The modification presented here aims at more sustainable shortening and widening of the mesosigmoid by including all its layers in the procedure. Of 31 consecutive patients with sigmoid volvulus operated on in Malawi in East Africa, 14 had the nongangrenous variety. Twelve of them underwent modified mesosigmoidoplasty without any major perioperative complications. There was one relaparotomy following misdiagnosis of cryptic Hirschsprung's disease and one true recurrence secondary to a technical error during the previous operation. During a follow-up of eight patients for 4 to 8 months, there were no complaints about abdominal discomfort or changed stool habits. Thus including all layers of the mesosigmoid in the plastic procedure did not increase short-term morbidity and in theory should be advantageous in respect to preventing recurrence. Applying it to a larger series with prolonged follow-up seems to be justified.
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PMID:Modification of mesosigmoidoplasty for nongangrenous sigmoid volvulus. 1603 50

The etiology of cryptic pregnancy has not been fully elucidated and there exist misconceptions about this phenomenon in our contemporary Nigerian society. This case presents the first case report of cryptic pregnancy in sub-Saharan Africa. A case of a 19 year old overweight female student who presented to the sick bay at 01: 30 hours with a 3-day history of lower back pain, abdominal discomfort and constipation. At the sick bay the general practitioner on call asked if she was pregnant and she vehemently said no, recounting that she sees her menstruation regularly. Abdominal examination however, revealed a gravid uterus of about 36 weeks and vaginal examination showed a fully dilated cervix. She was surprised, terrified and confused and only remembered having unprotected sexual intercourse many months earlier. Barely two hours later, she gave birth via spontaneous vaginal delivery, to a live female infant at 03: 14 hours. This case emphasizes the need for general practitioners and specialists in sub-Saharan Africa to be aware of the phenomenon of cryptic pregnancy, which involves women not being conscious of their gravid state until final weeks of gestation or at delivery, to reduce neonatal and maternal complications.
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PMID:Unexpected delivery: a case report of cryptic pregnancy in Nigeria. 3296 71