Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0232487 (abdominal discomfort)
 1,724 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From Sep. 1988 to Dec. 1989, 163 patients with gallstones and 7 with choledocholith were treated by biliary extracorporeal shock wave lithotripsy (ESWL). After lithotripsy, ursodeoxycholic acid was administered in 74 patients, and self-made lithoexpulsive in 44 patients. The remaining 52 patients were given both ursodeoxycholic acid and lithoexpulsive. The total rate of stone fragmentation was 97.6%. One hundred and twenty patients were followed up after ESWL. Biliary stones disappeared in 26.6% of the patients within one month after ESWL, in 33.3% within one to three months, and in 36.6% within six to eight months. There were no severe complications. 10.1 percent of the patients had abdominal discomfort during the procedure of ESWL, and cutaneous petechiae were found in 12.2% of the patients. Other complications included biliary colic in 6, jaundice in 2, and hematuria in 2. Serum enzymology and chest X-ray remained unchanged after ESWL.
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PMID:[Extracorporeal shock wave lithotripsy in the treatment of biliary stones]. 209 51

Over 500,000 patients undergo cholecystectomy annually in the United States for symptoms of upper abdominal discomfort and pain ascribed to gallbladder disease. However, approximately 5%, or 25,000 of these cases do not have gallstones on ultrasound examination but typically present with chronic symptoms of biliary colic. These patients often present as challenging diagnostic dilemmas and are often treated as if their symptoms are secondary to peptic ulcer disease or other gastrointestinal-related disorders. In 1992, we began to use the cholecystokinin (CCK) challenge test on patients with normal ultrasound examinations of the gallbladder but who had chronic symptoms resembling biliary colic. The CCK test was considered positive if the identical symptoms of discomfort or pain, usually in the right upper quadrant of the abdomen, were reproduced. This study describes the first 24 patients who had a positive CCK challenge test and chose to undergo cholecystectomy for relief of their symptoms. No patient was lost to follow-up evaluation at 1 to 24 months after operation.
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PMID:Chronic acalculous cholecystitis: reproduction of pain with cholecystokinin and relief of symptoms with cholecystectomy. 1038 44