Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0231835 (tachypnea)
 2,543 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Analysis of +Gx tolerance of 15 members of short-term ISS missions and 9 members of long-term ISS missions aboard the Soyuz vehicles showed good tolerance during insertion and satisfactory during descent provided the use of in-flight countermeasures and anti-g suit Kentaur inside the vehicle. Objective data about the tolerance of off-nominal +Gx (6.26 and 8.1 G) pointed to a more pronounced sinus tachycardia and tachypnea in a ballistic descent following long-duration weightlessness as compared with nominal. Physiological deviations were transient, functional by character. Cardiac arrhythmia was largely observed during return to Earth. Two cosmonauts were found to develop prognostically unfavorable ECG indications during off-nominal descent. Main factors in these deviations could be age (above 45) and existence of some individual specifics of cardiac rhythm regulation. These results emphasize the necessity of more careful screening of candidates older than 45 years, as weightlessness may impact their general condition and tolerance of g-loads during return to Earth.
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PMID:[+Gx-tolerance by the Cosmonauts of ISS crews 1, 6-9 and visiting crews 1-7 aboard Soyuz vehicles]. 1644 46

Physiological reactions to +Gx loads of 10 nonprofessional members of 8 to 12-d. missions to the ISS some of whom had partial health defciency were compared with data about space station MIR cosmonauts (n=10) who participated in flights of similar duration but were qualified as essentially healthy. Age of the ISS visitors varied between 29 and 60 years, whereas the MIR cosmonauts were 31 to 49 years old. Based on analysis of objective information, the ISS visitors were distinguished by much more pronounced sinus tachycardia and tachypnea during insertion and re-entry. There were several instances of pre-launch extrasystole arrhythmias that persisted during insertion and were, as a rule, more serious during re-entry. Also, descent from orbit caused more frequent cardiac rhythm disturbances, polymorphism and severity in these space flyers in comparison with the MIR cosmonauts. Particularly grave ECG deviations were observed in two 60-y.o. crew members. However, all these disturbances were episodic by character. These results suggest that development of individual programs of medical risk mitigation for nonprofessional flyers to the ISS should give regard for the status of cardiac rhythm regulation as re-entry g-loads may affect ECG dramatically. Besides, the analysis highlighted the necessity of more rigorous selection of aged candidates for ISS missions with partial health deficiency
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PMID:[Peculiar physiological reactions to +Gx loads of nonprofessional members of short-term missions to the ISS]. 1790 51