Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0231807 (exertional dyspnea)
 3,402 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Transient receptor potential cation channel subfamily M member 4 10.6
kid 9.2
PER1 protein 9.2
C-terminal tensin-like 9.1
TNS4 9.0
ABHD2 9.0
DMRT2 8.5
BPGM 8.2
Mulibrey nanism 8.1
V4-6 8.1
ADMP 8.0
SLC34A2 8.0
TRIM37 7.9
DLST 7.9
phosphate cyclase 7.9
pregnancy-specific protein 7.8
Thyrotropin receptor 7.8
HPS1 7.7
NPP2 7.6
ERO 7.4
NPI-1 7.4
phosphatidic acid phosphohydrolase 7.4
BCO2 7.3
MyBP-C 7.3
V1-2 7.1
RLF 7.0
NAR 7.0
RAPA 6.9
high molecular weight mucin 6.9
ACVRL1 6.7
calmodulin-dependent phosphodiesterase 6.7
VCAN 6.7
RNF213 6.7
NCF 6.6
periplakin 6.5
Hermansky-Pudlak syndrome 6.5
DIP 6.4
SS-A 6.4
GCR 6.4
CMAP 6.4
STP 6.3
TLE1 6.3
HIF2A 6.3
DOD 6.3
POEM 6.3
HB3 6.2
U1-70K 6.2
abc 6.2
CCND3 6.2
HPS 6.1
FEV 6.1
TC4 6.0
TRT 6.0
MAML2 6.0
CNRS 6.0
Maltase 6.0
follicle stimulating hormone receptor 6.0
ACTA1 6.0
TRD 5.9
Sho 5.9
TA1 5.8
gasdermin 5.8
LAM 5.8
M3 muscarinic receptor 5.7
COPD 5.7
EPOR 5.6
TLR10 5.6
NSF 5.6
ARM 5.6
She 5.6
CPK 5.6
MEP 5.5
EPAS1 5.5
SS-B 5.5
TRPM4 5.4
RFI 5.4
AG1 5.4
P210 5.4
FGA 5.4
BII 5.4
xenin 5.3
cholinephosphotransferase 5.3
ATS 5.3
transcobalamin II 5.3
CTM 5.3
DMRT1 5.3
BAL 5.3
PSR 5.2
GBP 5.2
ERA 5.2
GPE 5.2
CPX 5.2
PCN 5.2
C35 5.2
DMR 5.1
swan 5.1
SASP 5.1
GLS 5.1
NRC 5.1
TRE 5.1
NP1 5.0
FDP 5.0
4 domains 5.0
peptidoglycan recognition protein 5.0
BNP 5.0
MER 5.0
SP-D 5.0
CD138 4.9
PRKAR1A 4.9
TIP 4.9
USP6 4.9
DDH 4.9
classical) 4.9
BSS 4.9
SP-A 4.9
IB1 4.8
desmoglein 3 4.8
ASH 4.8
CEL 4.8
DAI 4.8
FAA 4.8
PER1 4.8
ALK1 4.8
CA-125 4.8
Was 4.7
SSA 4.7
AGL 4.7
OPD 4.7
prostaglandin I2 4.7
CSP 4.7
CD1a 4.7
L18 4.6
L100 4.6
myocilin 4.6
putative function 4.6
SVD 4.6
CA15 4.6
G15 4.6
CTR 4.6
VGLUT1 4.5
RPC 4.5
IVA 4.5
HMP 4.5
MART-1 4.5
luteinizing hormone receptor 4.5
CAE 4.5
CPAP 4.5
mover 4.5
muscle glycogen phosphorylase 4.4
ASD 4.4
GSC 4.4
BCM 4.4
ANA 4.4
ADAMTS-13 4.4
Emery-Dreifuss muscular dystrophy 4.4
Tissue plasminogen activator 4.3
Metalloproteinase 4.3
growth hormone receptor 4.3
MEA 4.3
SSB 4.3
more...
Disease
Hypertensive heart failure 12.2
Infundibular pulmonic stenosis 12.2
Pulmonary arteritis 11.6
Panlobular emphysema 11.2
Haemorrhagic pericarditis 11.2
Drug-induced cardiomyopathy 11.2
Summer-type hypersensitivity pneumonitis 11.0
Hydrallantois 10.9
Acute histoplasmosis 10.9
Respiratory bronchiolitis-associated interstitial lung disease 10.8
Thromboembolic pulmonary hypertension 10.6
Mediastinal fibrosis 10.4
Systemic sclerosis sine scleroderma 10.4
Chylous effusion 10.4
Silo Filler's Disease 10.2
Chronic respiratory failure 10.2
High output heart failure 10.2
type C thymoma 10.2
Cardiac beriberi 10.2
tracheal neoplasm 10.0
Cardiovascular beriberi 10.0
Paramphistomosis 10.0
Complete left bundle branch block 9.9
Laryngeal web 9.9
Bone Dysplasia 9.5
bird fancier's lung 9.4
Familial Hypertrophic Cardiomyopathy 9.3
Lofgren's syndrome 9.3
Pulmonary lymphangioleiomyomatosis 9.3
Secondary immunodeficiency 9.2
Campbell de Morgan spots 9.1
chronic bronchiolitis 9.1
Pulmonary alveolar microlithiasis 9.0
Necrotizing sarcoid granulomatosis 8.9
Diffuse alveolar damage 8.7
Drug-induced immune hemolytic anemia 8.7
Endobronchial lipoma 8.7
Fibrosing mediastinitis 8.6
BALT lymphoma 8.6
pentalogy of Fallot 8.5
A-V malformation 8.4
Restrictive lung disease 8.4
lithopedion 8.4
pleural neoplasm 8.4
High altitude pulmonary edema 8.3
Systolic heart failure 8.3
Pulmonary vein stenosis 8.3
Lutembacher 8.3
Pulmonary arteriovenous fistula 8.2
lymphangiomyoma 8.2
Cryptococcal infections 8.2
leukoerythroblastosis 8.1
Meigs' syndrome 8.0
Histoplasma capsulatum infection 8.0
Nonspecific interstitial pneumonia 8.0
Brown-Vialetto-Van Laere syndrome 7.9
Cardiac myxoma 7.9
hypersensitivity pneumonitis 7.9
tricuspid stenosis 7.9
Malignant Pleural Mesothelioma 7.9
NSIP 7.9
Diaphragmatic eventration 7.9
Pulmonary Langerhans cell histiocytosis 7.8
Mycobacterium abscessus infection 7.8
Interrupted aortic arch 7.8
Pulmonary capillary hemangiomatosis 7.8
Left ventricular thrombus 7.8
Pulmonary congestion 7.8
Chronic eosinophilic pneumonia 7.8
talcosis 7.8
polyarticular arthritis 7.8
Pulmonary eosinophilia 7.7
myxosarcoma 7.7
interstitial pneumonia 7.7
Aortocaval fistula 7.7
Pulmonary veno-occlusive disease 7.7
sinobronchial syndrome 7.6
sclerokeratitis 7.6
Constrictive pericarditis 7.6
Bronchiolitis obliterans organizing pneumonia 7.6
Portopulmonary hypertension 7.6
pulmonary alveolar proteinosis 7.6
Microangiopathic hemolytic anemia 7.6
sacralization 7.5
ovarian endometrioid adenocarcinoma 7.5
lymphangioleiomyomatosis 7.5
Intracardiac thrombus 7.5
Exercise-induced bronchospasm 7.5
Mobitz 7.5
Single coronary artery 7.5
Tracheal stenosis 7.5
MacLeod 7.5
Intravenous leiomyomatosis 7.5
Papillomatosis 7.4
cardiac aneurysm 7.4
type AB thymoma 7.4
fibrothorax 7.4
Botryomycosis 7.4
Pulmonary thromboembolism 7.4
Pannus 7.3
Paget-Schroetter syndrome 7.3
Pulmonary nocardiosis 7.3
pigmented skin lesion 7.3
recurrent thymoma 7.3
reactive airway disease 7.3
Giant cell myocarditis 7.3
Carcinoid heart disease 7.2
Abdominal pregnancy 7.2
Splenic artery aneurysm 7.2
adiaspiromycosis 7.2
lymphocytic thymoma 7.2
metastatic esophageal cancer 7.1
Pulmonary cryptococcosis 7.1
Plasmacytoma 7.1
tricuspid regurgitation 7.1
Polycystic liver disease 7.1
esophageal web 7.1
hemangiomatosis 7.1
pleural plaque 7.0
HHT2 7.0
subacute endocarditis 7.0
carcinoma of unknown origin 7.0
hydrometra 7.0
Weingarten 7.0
multifocal atrial tachycardia 7.0
right heart failure 7.0
primary pulmonary hypertension 7.0
yellow nail syndrome 7.0
pericardial effusion 7.0
Idiopathic pulmonary arterial hypertension 7.0
first degree atrioventricular block 7.0
interstitial lung disease 6.9
Auditory neuropathy 6.9
Plummer-Vinson syndrome 6.9
bronchorrhea 6.9
Hemophagocytosis 6.9
bronchomalacia 6.9
Diffuse panbronchiolitis 6.8
pulmonary infarction 6.8
fibrous mesothelioma 6.8
Glomus tumor 6.7
blepharophimosis-ptosis-epicanthus inversus syndrome 6.7
pulmonic stenosis 6.7
neurocirculatory asthenia 6.7
HHT 6.7
Miliary tuberculosis 6.7
UIP 6.7
Parsonage-Turner syndrome 6.7
scleromyxedema 6.7
Sarcomatoid carcinoma 6.6
broncholithiasis 6.6
Hypereosinophilia 6.6
Jaccoud 6.6
metastatic rectal cancer 6.6
Morquio A syndrome 6.6
beriberi 6.6
chylopericardium 6.6
DIP 6.6
pyopneumothorax 6.5
Purulent pericarditis 6.5
more...
Symptom
exertional dyspnea 13.2
orthopnea 10.1
Dyspnea at rest 10.0
Massive edema 9.3
pedal edema 8.6
non-productive cough 8.5
productive cough 8.4
cold sweats 8.4
abnormal taste 8.3
rales 8.2
Acute dyspnea 8.2
clubbing 8.0
Exercise intolerance 7.9
Cardiovascular symptoms 7.8
pleuritic chest pain 7.8
Ortner's syndrome 7.7
epigastric distress 7.6
leg edema 7.6
Amaurosis fugax 7.5
localized edema 7.5
chest tightness 7.4
atypical chest pain 7.3
persistent cough 7.3
chronic cough 7.2
brittle nails 7.2
cough 7.1
presyncope 7.1
cyanosis 7.0
dyspnea 7.0
diastolic murmurs 7.0
Overlying 6.7
Respiratory symptoms 6.6
hemoptysis 6.6
chest pain 6.5
wheezing 6.4
Physical findings 6.4
nocturnal cough 6.4
shortness of breath 6.2
syncopal episodes 6.2
night sweats 6.1
syncope 6.1
leg cramps 6.0
menometrorrhagia 5.9
decreased appetite 5.8
precordial pain 5.7
stridor 5.7
regurgitation 5.7
hoarseness 5.6
giddiness 5.5
giddiness 5.5
abdominal fullness 5.5
aphonia 5.2
lightheadedness 5.2
emaciation 5.1
acute low back pain 5.1
dark urine 5.1
tachypnea 5.1
lassitude 5.0
chills 4.9
fatigue 4.9
pallor 4.7
Ill 4.7
hepatomegaly 4.7
angina 4.7
dizziness 4.7
arthralgia 4.6
weakness 4.4
nasal discharge 4.4
Halo 4.3
oliguria 4.3
dysesthesia 4.3
hepatosplenomegaly 4.3
eds 4.1
nasal congestion 4.0
incoordination 4.0
discomfort 3.9
tingling 3.9
fasciculation 3.9
dry eye 3.8
asthenia 3.8
discomfort 3.8
anorexia 3.8
CSR 3.8
tense 3.7
myalgia 3.7
flushing 3.6
intestinal bleeding 3.5
consciousness disturbance 3.5
hypocapnia 3.5
wrist pain 3.5
abdominal discomfort 3.4
back pain 3.4
sore throat 3.3
snoring 3.3
respiratory distress 3.3
hypercapnia 3.2
HSA 3.2
erythema 3.2
dry skin 3.2
leg pain 3.2
blurred vision 3.2
microbial colonization 3.1
flank pain 3.1
polydipsia 3.1
urinary frequency 3.1
hypoproteinemia 3.0
rhinorrhea 3.0
epigastric pain 3.0
paresis 3.0
paresthesia 2.9
hypertonia 2.9
Mills 2.9
masculinization 2.9
cachexia 2.7
lethargy 2.7
nausea 2.7
collapse 2.6
anosmia 2.6
physical appearance 2.6
photophobia 2.6
abdominal pain 2.5
numbness 2.4
hypothermia 2.4
vertigo 2.4
fever of unknown origin 2.2
chorea 2.2
dysuria 1.9
low back pain 1.9
hyperoxia 1.8
exhaustion 1.8
paraparesis 1.8
shoulder pain 1.8
thinning 1.7
knee pain 1.7
hunger 1.7
agitation 1.6
polyuria 1.6
vomiting 1.6
diarrhea 1.6
splenomegaly 1.5
headache 1.5
cerebellar ataxia 1.4
memory loss 1.4
tremor 1.3
spasm 1.3
dysarthria 1.3
acute pain 1.2
anesthesia 1.2
apathy 1.2
sleepiness 1.1
distraction 1.0
constipation 0.9
insomnia 0.8
ENT 0.8
spasticity 0.5
tinnitus 0.5
pain 0.4
ataxia 0.2
dystonia 0.2
nausea and vomiting -0.0
more...
Drug
Mecobalamin 9.5
Benazepril hydrochloride 9.1
Histoplasmin 8.7
Bisolvon 8.4
Spiriva 8.1
Bucillamine 7.9
Clove oil 7.7
Pirfenidone 7.3
Cordarone 7.3
Sulla 7.2
Cordarone 7.0
Cibenzoline 6.8
Alprenolol 6.8
Lepirudin 6.8
Mizoribine 6.6
Talc 6.4
Mesalazine 6.4
Trandolapril 6.3
Prednisolone 6.2
Vena 5.9
Vena 5.9
Diamox 5.9
Swainsonine 5.8
RSM 5.7
SNL 5.7
Bosentan 5.5
Bosentan 5.5
CTM 5.3
Isoptin 5.2
Helium 4.9
Myricetin 4.9
CTM 4.8
Coumadin 4.8
Prednisone 4.8
Orlistat 4.6
Ipilimumab 4.5
Omalizumab 4.5
Vitamin B12 4.5
Trifluoperazine 4.4
MEA 4.4
Methylprednisolone 4.4
Valsartan 4.3
Citric acid 4.2
Diphenhydramine 4.2
Adalimumab 4.1
Sinemet 4.1
PPA 4.0
MOF 4.0
Ganciclovir 3.6
Bupivacaine 3.6
Acacia 3.5
Atenolol 3.5
Docetaxel 3.4
Oxaliplatin 3.3
Cetuximab 3.3
Isoniazid 3.3
Theophylline 3.2
EPA 3.2
Salbutamol 3.2
Dakar 3.1
MRC 3.0
Herceptin 3.0
CEC 3.0
RFP 2.9
CCL 2.9
MAP 2.8
Rituximab 2.7
BH4 2.6
Coral 2.6
DM1 2.6
Triclosan 2.6
Cardiovasc 2.6
Bevacizumab 2.4
PCP 2.3
CPT-11 2.3
Itraconazole 2.2
Portal 2.2
ACT 2.1
MDS 2.1
Adriamycin 2.0
Imatinib 1.9
pyridoxal phosphate 1.9
Asthma 1.9
Nitric Oxide 1.8
Forskolin 1.8
HCG 1.8
ETA 1.8
Ringer's solution 1.7
CAM 1.7
nitroglycerin 1.7
Mutagen 1.7
Heme 1.6
Indomethacin 1.6
lactose 1.5
ampicillin 1.2
Leaf 1.1
ABC 1.1
Ethanol 0.9
Glutathione 0.8
FAD 0.8
SiO2 0.7
CaCl2 0.6
CaCl2 0.6
CaCl2 0.5
Monit 0.4
Gel 0.3
ROC 0.3
ENT 0.1
vitamin E 0.1
citric acid -0.1
CTX -0.1
NADH -0.2
caffeine -1.2
ascorbate -1.3
Dermatol -2.2
Enzyme
mannosyl-3-phosphoglycerate phosphatase 10.4
mannosyl-3-phosphoglycerate synthase 9.7
3-phosphoglycerate phosphatase 9.6
2-oxopent-4-enoate hydratase 8.9
CDP-diacylglycerol synthase 7.6
myo-inositol oxygenase 6.9
phosphoglyceromutase 5.6
amylomaltase 5.5
phosphatidate phosphatase 5.5
phosphocholine cytidylyltransferase 5.4
phenol hydroxylase 5.3
PHT 5.2
BAL 5.2
lysophosphatidylcholine acyltransferase 5.2
methylamine dehydrogenase 5.1
proteinase-3 4.8
nitrous oxide reductase 4.7
methanol dehydrogenase 4.5
choline kinase 4.4
malate synthase 4.2
TRS 4.2
branching enzyme 3.9
NAT 3.8
PHD 3.4
BMT 3.4
Rex 3.3
isocitrate lyase 3.2
lactase 3.1
PAH 3.1
aldolase 3.0
lecithin:cholesterol acyltransferase 3.0
transketolase 2.9
LPL 2.8
MAP 2.7
urokinase-type plasminogen activator 2.6
alpha-galactosidase 2.5
paraoxonase 2.5
PCP 2.3
creatine kinase 2.3
paraoxonase 2.2
NADH dehydrogenase 2.1
CAD 2.1
CAD 2.1
CAD 2.0
sucrase 2.0
MIP 1.9
adenosine deaminase 1.9
adenosine deaminase 1.8
ACE 1.8
lactate dehydrogenase 1.8
phosphodiesterase 1.8
phosphorylase 1.7
tissue plasminogen activator 1.7
guanylate cyclase 1.7
carboxylesterase 1.6
thyroid peroxidase 1.6
STR 1.6
thromboplastin 1.5
CPT 1.4
pyruvate dehydrogenase 1.4
hydrogenase 1.4
pyruvate dehydrogenase 1.4
hydrogenase 1.4
CD13 1.4
aspartate aminotransferase 1.4
nitrogenase 1.4
arginase 1.3
neutrophil elastase 1.2
alpha-glucosidase 1.1
MMP 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
laccase 1.0
glyceraldehyde-3-phosphate dehydrogenase 1.0
CD10 0.9
invertase 0.9
ceruloplasmin 0.9
alpha-amylase 0.8
monoamine oxidase 0.8
lysozyme 0.8
peroxidase 0.8
pyruvate dehydrogenase 0.8
glyceraldehyde-3-phosphate dehydrogenase 0.7
diaphorase 0.7
AST 0.6
CYP3A4 0.6
acid phosphatase 0.5
glyceraldehyde-3-phosphate dehydrogenase 0.5
aldehyde dehydrogenase 0.5
papain 0.5
cellulase 0.5
phospholipase A2 0.4
carbonic anhydrase 0.3
thymidine kinase 0.3
beta-glucuronidase 0.3
APC 0.2
succinate dehydrogenase 0.2
xanthine oxidase 0.2
lipoxygenase 0.1
complex I 0.1
alanine aminotransferase 0.1
gamma-glutamyl transpeptidase 0.0
glutathione reductase -0.0
ERK -0.0
alkaline phosphatase -0.0
phosphatidylinositol 3-kinase -0.2
focal adhesion kinase -0.6
tyrosine hydroxylase -0.7
NO synthase -0.8
reverse transcriptase -0.8
renin -0.9
lipase -1.0
adenylate cyclase -1.0
glutathione S-transferase -1.3
proteasome -1.6
superoxide dismutase -1.7
ATPase -1.8
thrombin -1.8
ACS -2.1
catalase -2.6
mitogen-activated protein kinase -3.4
Compound
DOE 13.1
C6H10O2 12.2
Bleomycin sulfate 9.6
Urushiol 9.4
SLEX 8.8
Amiodarone hydrochloride 8.0
GDP-glucose 7.7
Epichlorohydrin 7.6
Betamethasone 7.4
2-butenoic acid 7.1
2-butenoic acid 6.9
Medroxyprogesterone 6.9
Hydromorphone 6.8
Sulfadoxine 6.6
Prednisolone 6.5
DOD 6.4
1-undecanol 6.2
STP 6.2
TDI 6.2
Ferrous sulfate 6.2
TRU 6.2
MCNU 6.1
Beryllium 6.1
CD 3 6.1
A 71 6.1
A 42 6.1
GDP-D-mannose 6.0
Lomefloxacin 6.0
Practolol 5.9
Leflunomide 5.9
EDAP 5.7
ANI 5.7
C56 5.7
Mesalamine 5.6
Bisoprolol 5.6
Swainsonine 5.6
MEP 5.5
9H-fluorene 5.5
MEP 5.4
BCM 5.3
EBT 5.3
Salmeterol 5.3
PHT 5.2
Pentamidine 5.2
PCN 5.1
Lithium chloride 5.1
Protect 5.1
Ethambutol 5.0
Nitrofurantoin 5.0
Thiopental 5.0
BAL 4.9
Akron 4.9
BEP 4.9
BNP 4.9
Amiodarone 4.8
FDP 4.8
Tannin 4.8
Mefloquine 4.7
Mefloquine 4.7
Neostigmine 4.7
ANCA 4.6
acenaphthylene 4.6
Pindolol 4.6
Pyrroloquinoline quinone 4.6
acenaphthylene 4.6
pentadecanoic acid 4.5
pentadecanoic acid 4.5
Methylprednisolone 4.5
Phencyclidine 4.4
Trifluoperazine 4.4
MEA 4.4
SVC 4.3
Venlafaxine 4.3
Ceftriaxone 4.3
Ivermectin 4.3
Zirconia 4.2
DHBA 4.2
Sulfamethoxazole 4.2
CH3I 4.1
Inositol 4.1
Prednisone 4.1
PGFM 4.1
DHBA 4.0
Lutein 4.0
Chlorhexidine 4.0
Trimethoprim 4.0
Thiamine 3.9
PYR 3.9
MCH 3.8
Docetaxel 3.8
PPA 3.8
Quinone 3.7
Carvedilol 3.7
1,1,1-trichloroethane 3.7
ANA 3.7
ANA 3.7
DES 3.7
DMP 3.7
Lamotrigine 3.6
DMP 3.6
Bupivacaine 3.6
DMP 3.6
ISDN 3.6
Levamisole 3.6
His 3.6
DOP 3.6
Guo 3.6
2,3-butanediol 3.6
2,3-butanediol 3.6
PAS 3.6
2,3-butanediol 3.6
Dithiothreitol 3.5
Pentoxifylline 3.5
prostacyclin 3.5
Temozolomide 3.5
Acetazolamide 3.5
AAT 3.4
Dobutamine 3.3
Nodular 3.3
MVA 3.3
Progesterone 3.3
Celecoxib 3.3
CMP 3.3
Congo red 3.3
Corticosterone 3.2
TMP 3.2
Azathioprine 3.2
EPA 3.2
CMP 3.2
TMP 3.2
TCM 3.2
Salbutamol 3.2
TCM 3.2
PID 3.2
TMP 3.2
PID 3.1
prostaglandin F2alpha 3.1
Cortisol 3.1
succinic acid 3.1
succinic acid 3.1
succinic acid 3.1
succinic acid 3.1
PAH 3.1
Dipyridamole 3.0
Dipyridamole 3.0
Dipyridamole 3.0
Dipyridamole 3.0
Isoproterenol 3.0
Carnitine 3.0
protocatechuate 3.0
Hydroxyurea 3.0
Glycogen synthase 3.0
Oil Red O 3.0
Guo 3.0
Digoxin 3.0
Parenteral 2.9
LTD 2.9
Ribavirin 2.9
Prostaglandin 2.9
Prostaglandin 2.9
more...