Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0231807 (exertional dyspnea)
 3,402 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Calcifying fibrous tumors (CFTs) are rare lesions that occur throughout the body. A 35-year-old man presented with exertional dyspnea. Computed tomography showed a polypoid mass abutting pericardium, diaphragm, and left chest wall, and a pleural-based lesion adjacent to T12. Thoracoscopy revealed a large mass with diaphragmatic stalk, two pleural-based nodules and four diaphragmatic nodules. Pathological analysis of resected lesions showed CFT. Three lesions contained heterogenous mutations associated with this tumor type. The patient is disease-free one-year later. CFTs should be recognized as rare multifocal pleural and diaphragmatic-based tumors. Complete resection leads to excellent survival for patients with this uncommon disease.
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PMID:MULTIFOCAL CALCIFYING FIBROUS TUMOR AT SEVEN INTRATHORACIC SITES IN ONE PATIENT. 3268 54