Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0231807 (exertional dyspnea)
 3,402 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The structural and kinetic parameters of the oxidative phosphorylation system responsible for synchronization of the respiratory chain and ATP-synthetase function in mitochondria were studied. It was shown that regulation of ATP-synthetase function by the respiratory chain can be realized only within the whole ATP-synthetase complex (F0F1). NADH dehydrogenase and succinate dehydrogenase doe not control synchronization of ATP-synthetase function in the mitochondria. Data from the inhibitory analysis suggest that the ATP-synthetase function depends on the rate of the enzyme operation but not on the redox state of the respiratory chain carriers.
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PMID:[Structural and kinetic parameters of the oxidative phosphorylation system, participating in the synchronization of mitochondrial respiratory chain and ATP-synthetase functions]. 632 63