Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0231749 (knee pain)
 2,815 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
matrilin 3 10.1
cartilage glycoprotein-39 9.5
SCGF 9.0
SH3-domain binding protein 2 8.9
COL27A1 8.8
ORC6 8.5
GRO-gamma 8.5
GNPTG 8.4
ORC4 8.1
Strap 7.9
TKR 7.9
FGS 7.9
SLC34A3 7.8
immunoglobulin kappa chain 7.8
stem cell growth factor 7.6
ALS4 7.5
PERP 7.5
CG2 7.4
ACL 7.3
EDNRA 7.2
HHA 7.2
KIN 7.0
CG1 6.9
CDT1 6.9
TOB 6.8
CDC73 6.7
COL11A2 6.6
ORC1 6.5
SLC2A9 6.5
Fez 6.5
DSR 6.4
Cam 5.9
TRIP 5.9
CIR 5.8
MSK1 5.6
CDC6 5.6
GDF5 5.4
STG 5.4
HSS 5.3
LITAF 5.3
TUG 5.3
KAT 5.2
matrix metalloproteinase 1 5.1
POR 5.1
ADL 5.0
Hip 5.0
Rheumatoid factor 5.0
heparin-binding protein 4.9
alpha-1-antichymotrypsin 4.9
complement) 4.9
AOA 4.8
MSK 4.7
BTR 4.7
COMP 4.7
PFP 4.6
dysferlin 4.6
YKL-40 4.5
MDP 4.5
ROM 4.5
MTC 4.5
CASP3 4.5
SMD 4.4
OTA 4.4
swan 4.4
CST 4.4
MRI 4.4
sit 4.3
RTA 4.3
CD161 4.2
PRP 4.1
glucosamine 4.1
CAN 4.1
ankylosing spondylitis 4.0
She 4.0
PCS 4.0
FAT 4.0
Dance 3.9
BPI 3.9
MMP13 3.9
MCS 3.9
more...
Disease
bursopathy 12.5
Sinding-Larsen 12.4
Osteochondritis dissecans of the patella 12.1
Synovial plica 11.9
Patellofemoral pain syndrome 11.8
Iliotibial band syndrome 11.5
Sinding-Larsen-Johansson disease 11.5
Chronic osteoarthritis 11.3
Hoffa 11.2
Calcific periarthritis 11.1
Plica syndrome 11.1
Muscle tightness 11.1
Osgood-Schlatter disease 11.0
Patellofemoral osteoarthritis 10.9
alcohol related disorder 10.9
patellofemoral disorders 10.7
Hypermobility syndrome 10.5
Prosthetic infection 10.5
Patellar tendinitis 10.1
chondromalacia patellae 9.9
Juvenile osteochondritis 9.8
chondromalacia 9.8
osteoarthritis of the knee 9.7
Bone marrow edema 9.7
Fibroma of tendon sheath 9.6
lumbar spondylosis 9.6
apophysitis 9.5
Soft Tissue Tumor 9.5
Lequesne 9.4
popliteal cyst 9.2
Arthrofibrosis 9.2
tongue ulcer 9.2
cartilage disorder 9.1
Transient synovitis 9.0
sulfa allergy 9.0
Myositis ossificans circumscripta 9.0
Peroneal nerve palsy 9.0
Salmonella osteomyelitis 8.8
gonarthrosis 8.7
connective tissue hyperplasia 8.6
AOA2 8.6
psychological disability 8.6
joint effusion 8.4
tendinitis 8.4
Sever 8.4
Metallosis 8.3
prepatellar bursa 8.3
white leg 8.3
Blount 8.3
chondrolysis 8.3
Pigmented villonodular synovitis 8.3
Pigmented villonodular synovitis 8.3
arthritis of the knee 8.2
Parosteal osteosarcoma 8.1
Alveolitis 8.1
crystal arthropathy 8.1
calcifying tendinitis 8.1
villonodular synovitis 8.0
Achilles tendon pain 8.0
Bury 8.0
bursitis 7.9
Synovial osteochondromatosis 7.9
OCD 7.9
LCS 7.9
glomangioma 7.8
Hypertrophic pulmonary osteoarthropathy 7.8
Fibroma 7.7
osteoarthritis 7.6
Achilles tendinitis 7.6
pelvic instability 7.6
Freiberg 7.6
Phlegmasia cerulea dolens 7.6
chondroblastoma 7.6
hydroxyapatite deposition 7.6
chondromatosis 7.5
ML III 7.4
Erdheim-Chester disease 7.3
Kashin-Beck disease 7.3
Osteoid osteoma 7.3
osteochondritis 7.2
more...
Symptom
knee pain 13.5
Anterior knee pain 12.5
Painful scar 11.5
Q angle 10.2
Massive edema 9.6
Referred pain 9.3
Quadriceps weakness 9.1
toe pain 9.0
musculoskeletal disability 8.9
Stress symptoms 8.5
growing pains 8.4
Pain and tenderness 8.4
hip pain 8.2
elbow pain 8.0
Fear of falling 7.9
Fear of falling 7.9
Foot pain 7.9
Central pain 7.8
ankle pain 7.6
stump pain 7.6
lumbar back pain 7.0
gumma 7.0
thigh pain 6.9
generalized pain 6.8
shoulder pain 6.8
hand pain 6.8
Musculoskeletal symptoms 6.8
No pain 6.7
metatarsalgia 6.6
heel pain 6.6
arthralgia 6.6
Tenderness 6.5
groin pain 6.2
arm pain 6.1
low back pain 6.0
arm weakness 5.9
chronic back pain 5.9
clubbing 5.7
leg pain 5.6
Multimorbidity 5.6
back pain 5.6
pain 5.6
physical symptom 5.5
Stiffness 5.5
body pain 5.4
neck pain 5.1
limb pain 5.1
neuralgia 5.0
joint stiffness 5.0
acute pain 4.7
stomach pain 4.5
sciatica 4.4
discomfort 4.4
hyperesthesia 4.4
abdominal cramps 4.4
swollen joints 4.4
Postoperative pain 4.4
discomfort 4.3
abnormal gait 4.3
bone pain 4.2
numbness 4.1
leg edema 4.1
weakness 3.9
wrist pain 3.7
myalgia 3.6
erythema 3.6
dysesthesia 3.6
orofacial pain 3.6
hot flashes 3.4
urinary frequency 3.3
productive cough 3.3
decreased appetite 3.3
night sweats 3.2
overweight 3.2
paresthesia 3.2
thinning 3.2
chronic constipation 3.1
tonic-clonic seizure 3.1
asthenia 3.1
distraction 3.1
more...
Drug
Solon 7.8
Oxaprozin 7.5
Arthrex 7.1
Valdecoxib 7.0
AMK 6.9
CG1 6.8
Tapentadol 6.6
Duloxetine 6.2
Menthol 5.2
Glide 5.2
Domperidone 5.1
Orion 4.6
Posture 4.5
MTC 4.5
Vicryl 4.4
Adenosine triphosphate 3.6
THA 3.6
Growth hormone 3.5
Growth hormone 3.5
Infliximab 3.3
Infliximab 3.3
Fentanyl 3.1
Tacrolimus 2.8
Spectrum 2.5
Frontal 2.5
Dakar 2.4
NAG 2.4
Alliance 2.1
CTX 2.0
Rituximab 2.0
CTX 2.0
Nephron 1.9
CTX 1.2
G-CSF 1.1
ascorbate 1.0
PTH 0.7
Leaf 0.6
ROC 0.5
EE2 0.5
ENT 0.4
nitroglycerin 0.3
Ethanol 0.2
Monit -0.0
vitamin E -0.6
ROS -0.8
CSF -1.5
Cardiovasc -3.1
Dermatol -3.5
Enzyme
DSR 6.6
homogentisate 1,2-dioxygenase 5.9
botulinum neurotoxin 4.2
MDP 4.1
MCS 3.9
KAT 3.7
interstitial collagenase 3.6
bromelain 3.5
MMP-3 3.3
dihydropyrimidine dehydrogenase 3.2
tryptase 2.0
HSD 1.7
MMP 1.4
hyaluronidase 1.3
AST 0.9
collagenase 0.9
hyaluronidase 0.9
prostate-specific antigen 0.7
lysozyme 0.7
DNase 0.6
gamma-glutamyl transpeptidase 0.3
aspartate aminotransferase 0.1
alanine aminotransferase -0.2
tyrosine hydroxylase -0.4
calcineurin -0.6
MEK -0.7
ACE -0.7
catalase -0.7
creatine kinase -0.7
glutathione S-transferase -1.0
ERK -1.1
trypsin -1.9
alkaline phosphatase -2.1
superoxide dismutase -2.4
Compound
2,4-Di-tert-butylphenol 9.8
2,4-Di-tert-butylphenol 9.7
Anserine 8.5
Oxaprozin 8.1
ETN 7.9
Homogentisate 7.9
Reticulin 6.7
Glucosamine 6.6
maslinic acid 6.4
GML 6.3
BTO 6.2
Triamcinolone 5.6
D-glucosamine 5.5
Botulinum toxin type A 5.4
Menthol 5.2
Menthol 5.0
hyaluronic acid 5.0
Safranin O 4.9
Prone 4.9
BAS 4.5
Methacholine 4.5
A 42 4.5
MTC 4.4
Alendronate 4.4
A 71 4.3
Lutein 4.3
Alendronate 4.3
Safranin O 4.2
D-glucuronic acid 4.2
keratan sulfate 4.2
Tramadol 4.0
benzenesulfonamide 3.8
benzenesulfonamide 3.8
benzenesulfonamide 3.8
CAN 3.7
Nodular 3.6
Minocycline 3.6
THE 3.5
TCM 3.5
TCM 3.5
Diclofenac 3.4
Creatine 3.4
Isoproterenol 3.3
vinyl acetate 2.9
DMS 2.8
LSD 2.7
Ibuprofen 2.7
DOPAC 2.6
TCP 2.6
TCP 2.6
TCP 2.6
TCP 2.6
MSM 2.6
SPM 2.5
TTC 2.3
Cobalt 2.3
DTPA 2.3
6-12 2.2
N-acetyl-D-glucosamine 2.2
His 2.2
CIT 2.1
Austin 2.0
Substance P 1.8
Curcumin 1.8
DBP 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
benzaldehyde 1.5
more...