Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0221002 (
primary hyperparathyroidism
)
4,921
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
parathyroid hormone
1388
PTH
611
Sep
313
parathormone
271
alkaline phosphatase
206
calcitonin
139
chronic renal failure
131
She
121
HPT
90
osteocalcin
82
calcium-sensing receptor
79
MEN1
75
Parathyroid hormone
74
AMP
71
insulin
70
parathyroid hormone-related protein
68
albumin
63
MRI
60
parafibromin
55
RET
53
gastrin
48
thymus
44
CDC73
41
collagen
39
Pol
36
renin
34
Mol
34
FHH
33
menin
30
type I collagen
29
CaSR
27
calcium sensing receptor
27
cyclin D1
26
BMD
26
MEN2A
25
CDKN1B
22
reserved
22
RET proto-oncogene
22
GFR
21
prolactin
21
vitamin D receptor
20
glucagon
20
secretin
20
Calcitonin
18
growth hormone
17
serum albumin
16
p27(KIP1)
16
Osteocalcin
16
somatostatin
16
BGP
16
ZES
13
chromogranin A
13
ALP
13
Mal
12
thyroid hormone
12
AP17
11
acid phosphatase
11
pancreatic polypeptide
11
p53
11
proto-oncogene
10
neurofibromatosis
10
type I procollagen
10
tumour suppressor
10
JAMA
9
CCND1
9
ACTH
9
nodal
9
sclerostin
9
catenin
9
glycoprotein
9
guanine nucleotide binding protein
9
PTH/PTHrP
9
FDG
9
tartrate-resistant acid phosphatase
9
gut
8
CO2
8
Alkaline phosphatase
8
cytokine
8
p27
8
GCMB
8
more...
Disease
primary hyperparathyroidism
4921
hypercalcemia
1638
adenoma
1457
hyperparathyroidism
1412
tumor
575
cancer
456
carcinoma
416
multiple endocrine neoplasia
353
osteoporosis
298
hypoparathyroidism
216
bone disease
200
Parathyroid
196
nephrolithiasis
194
hypertension
192
hypercalciuria
172
Parathyroid carcinoma
157
chronic renal failure
141
parathyroid hyperplasia
122
MEN1
122
diabetes
114
metastases
113
renal failure
111
medullary thyroid carcinoma
104
vitamin D deficiency
104
osteitis
98
hyperthyroidism
93
pheochromocytoma
87
PDB
82
osteomalacia
80
urolithiasis
78
endocrine disorder
78
pancreatitis
74
renal disease
73
multiple myeloma
67
nephrocalcinosis
67
depression
58
acute pancreatitis
53
goiter
52
renal insufficiency
51
sarcoidosis
51
hypercalcemia of malignancy
45
Best
44
peptic ulcer
43
HRPT2
42
MEN 2
40
cardiovascular disease
39
thyroid cancer
38
acromegaly
37
tumorigenesis
37
bone metastases
37
uremia
37
breast cancer
35
thyroid nodule
35
Parathyroid adenoma
33
thyrotoxicosis
33
renal osteodystrophy
33
pseudohypoparathyroidism
31
hypothyroidism
30
renal tubular acidosis
30
Brown
30
Brown tumor
30
tetany
28
SEM
28
rare disease
27
BMD
26
renal impairment
26
dehydration
26
rickets
25
Cushing's syndrome
24
lymphoma
24
Zollinger-Ellison syndrome
24
gastrinoma
24
anemia
24
Familial hypocalciuric hypercalcemia
22
pathological fracture
22
insulinoma
22
carcinoid
21
malabsorption
21
aldosteronism
21
multinodular goiter
21
more...
Symptom
weakness
101
fatigue
77
pain
75
anesthesia
75
bone pain
52
polyuria
51
nausea
45
vomiting
40
constipation
37
abdominal pain
35
anorexia
31
polydipsia
30
lethargy
26
arthralgia
17
diarrhea
16
nausea and vomiting
14
headache
13
Ill
13
back pain
13
renal colic
12
seizures
11
asthenia
10
dyspnea
9
discomfort
9
discomfort
9
myalgia
9
respiratory distress
9
hypotonia
9
memory loss
8
epigastric pain
8
hoarseness
7
knee pain
6
thinning
6
paresthesia
5
low back pain
5
hepatosplenomegaly
5
acute abdomen
4
hunger
4
ENT
4
neck pain
4
colic
4
chest pain
4
agitation
4
hip pain
4
cough
3
angina
3
dizziness
3
hyperemesis
3
sleepiness
3
heartburn
3
exhaustion
3
Psychiatric symptoms
3
flank pain
3
apathy
3
Gastrointestinal symptoms
3
Stiffness
2
cyanosis
2
numbness
2
dysarthria
2
consciousness disturbance
2
dysuria
2
hyperemesis gravidarum
2
leg pain
2
sore throat
2
ataxia
2
analgesia
2
tingling
2
phosphatemia
2
shortness of breath
2
paraparesis
2
splenomegaly
2
pallor
2
chronic constipation
1
lassitude
1
paresis
1
stridor
1
clubbing
1
syncope
1
lump in the neck
1
trigeminy
1
more...
Drug
PTH
621
Cinacalcet
45
Nephron
10
APD
10
Cardiovasc
10
Gel
9
Dial
9
CTX
7
Nephron
7
CTX
7
ENT
7
CTX
7
Dermatol
7
CaCl2
6
MRC
6
CaCl2
6
CaCl2
6
Denosumab
5
MTC
5
Cimetidine
5
Cimetidine
5
Cinacalcet hydrochloride
4
EHDP
4
ROC
4
Albumin
4
lysine
4
Angiotensin II
3
Aredia
3
Leaf
3
Estrogens
3
DPA
2
Ipriflavone
2
Monit
2
Histamine
2
Zoledronic acid
2
Raloxifene
2
Clodronate
2
Spectrum
2
Dakar
2
Teriparatide
2
Methylene blue
2
Indocyanine green
2
Gallium nitrate
2
TAT
2
Growth hormone
2
Growth hormone
2
IL-11
2
Calcifediol
1
Portal
1
TAC
1
Bonefos
1
ALA
1
Sandostatin
1
Rocaltrol
1
Hypaque
1
Fraction
1
CSF
1
G-CSF
1
PTC
1
nitroglycerin
1
PCB
1
Prednisone
1
Indomethacin
1
DDAVP
1
Serum albumin
1
Ammonium chloride
1
Chloramine T
1
CAM
1
Fluorescein
1
Ketoconazole
1
Sandostatin
1
Meditec
1
DM1
1
Calcium gluconate
1
DDAVP
1
Hypaque
1
ADM
1
Fluorescein
1
Zoledronic acid
1
HCG
1
more...
Enzyme
alkaline phosphatase
206
ERK
60
renin
34
acid phosphatase
11
protein kinase
10
adenylate cyclase
8
MDP
7
APC
5
ATPase
5
MIP
5
protein kinase C
4
peroxidase
3
P-glycoprotein
3
PRA
3
TAT
2
ACS
2
succinate dehydrogenase
2
glucose-6-phosphate dehydrogenase
2
focal adhesion kinase
2
thyroid peroxidase
2
lysozyme
2
lipase
2
tyrosine hydroxylase
2
dihydropyrimidine dehydrogenase
2
catalase
2
ACE
2
collagenase
2
proline iminopeptidase
2
cathepsin K
2
mitogen-activated protein kinase
2
creatine kinase
2
PHT
2
calcium pump
2
DNA methyltransferase
1
CYP3A4
1
cholinesterase
1
NO synthase
1
RNase
1
AMP-activated protein kinase
1
transcriptase
1
luciferase
1
NQO1
1
urease
1
ascorbate oxidase
1
phosphodiesterase
1
glyceraldehyde-3-phosphate dehydrogenase
1
RNA polymerase
1
phosphofructokinase
1
1-hydroxylase
1
asparaginase
1
guanylate cyclase
1
isoamylase
1
TGT
1
AMPK
1
aspartate aminotransferase
1
neuraminidase
1
PDE
1
alpha-glucosidase
1
cytochrome oxidase
1
caspase-3
1
endonuclease
1
acetylcholinesterase
1
diaphorase
1
gamma-glutamyl transpeptidase
1
E-2
1
ribonuclease
1
prostaglandin synthetase
1
alanine aminotransferase
1
MEK
1
urease
1
ribonuclease
1
phosphorylase kinase
1
phospholipase C
1
CPT
1
RNase
1
homogentisate 1,2-dioxygenase
1
DNA polymerase
1
trypsin
1
hormone-sensitive lipase
1
prostate-specific antigen
1
more...
Compound
calcium
2092
Clin
792
Dec
374
vitamin D
310
phosphate
296
creatinine
210
phosphorus
176
HPT
90
cAMP
77
DNA
74
AMP
71
sodium
58
glucose
57
oxalate
42
Vitamin D
40
water
37
aldosterone
36
His
33
potassium
29
carbonate
28
Thyroid
28
EDTA
27
BMD
26
25-dihydroxycholecalciferol
25
EDTA
25
urea
23
iodine
22
ethanol
19
Calcitonin
18
salt
17
Estrogen
14
arginine
14
ALP
13
Estrogen
13
nitrogen
12
TSH
11
methionine
11
CO2
10
Insulin
10
ACTH
9
phosphoric acid
9
Dial
9
POP
8
Lithium
8
Mg2+
8
25-hydroxycholecalciferol
8
tyrosine
7
CTX
7
Alendronate
7
HCl
7
Alendronate
7
Cardiol
6
TRH
6
leucine
6
CaCl2
6
lysine
6
MTC
5
ammonium
5
6-12
5
tryptophan
5
NH2
4
barium
4
Adrenal
4
Octreotide
4
nitric oxide
4
Angiotensin II
4
noradrenaline
4
EHDP
4
iron
4
cGMP
4
oxygen
4
proline
4
Propranolol
3
GAL
3
strontium
3
nitrate
3
Uric acid
3
TAR
3
Propranolol
3
DBP
3
more...