Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0221002 (
primary hyperparathyroidism
)
4,921
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Digital
clubbing
is a rare clinical finding and usually represents a sign of underlying disease.There are only few cases of digital
clubbing
in patients with
primary hyperparathyroidism
or with secondary hyperparathyroidism (SHPT) during long-term hemodialysis. We haven't come across papers dealing with the relation of digital
clubbing
and SHPT caused by vitamin D deficiency. In this article, we report a case of 43 year-old female patient with prominent
clubbing
of the fingers and toes, and 22 year history of SHPT caused by vitamin D deficiency. Current radiographic findings of the hands and feet are actually uncommon, and they show massive osteolytic lesions of numerous phalanges, which is the consequence of long-time untreated SHPT. Besides, our patient has a rare case of neutrophils with bilobed nuclei and decreased cytoplasmic granularity. This paper for the first time describes digital
clubbing
as an unusual complication of the SHPT caused by vitamin D deficiency associated with atypical neutrophils.
...
PMID:Digital clubbing as an unusual complication of the secondary hyperparathyroidism associated with atypical neutrophils: a case report. 2309 Aug 21
