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Target Concepts:
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Query: UMLS:C0221002 (
primary hyperparathyroidism
)
4,921
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
There are several causes for ST segment abnormalities in leads V1 to V3. Hypercalcaemia and
Brugada syndrome
are among them. Both are known to produce ventricular arrhythmia, albeit only rare cases have been reported with documented evidence of ventricular arrhythmias in association with a hypercalcaemic crisis but none when hypercalcaemic coexists with
Brugada syndrome
. We describe a patient with
primary hyperparathyroidism
who presented with ventricular fibrillation, and the ECG showed changes similar to
Brugada syndrome
. The provocation test with flecainide was conducted twice. This was positive, both before and after parathyroidectomy when serum calcium and parathormone levels had normalized. The patient was treated for hypercalcaemia and underwent parathyroidectomy. This is the first report of oral flecainide test unmasking the diagnostic coved Brugada ECG pattern in a patient with
primary hyperparathyroidism
and raising attention to hypercalcaemia as a potential trigger for life-threatening arrhythmia in
Brugada syndrome
.
...
PMID:Brugada-like electrocardiographic pattern and ventricular fibrillation in a patient with primary hyperparathyroidism. 1734 7
