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Target Concepts:
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Query: UMLS:C0221002 (
primary hyperparathyroidism
)
4,921
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Among 8 of the 20 records of
primary hyperparathyroidism
examined in search of neurological and/or psychiatric manifestations, the authors extracted 5 clinical cases reported here. These 5 cases were selected because these manifestations had been well evaluated before and after curative surgery of the disease. Among the manifestations reported, there was one corpus striatum syndrome, one cervical
myelopathy
and three cases of "chronic" psychiatric disorders of several years duration completely cured after parathyroidectomy. The authors underline that such psychiatric disorders should be taken into account in the discussion of treatment.
...
PMID:[Neurologic and psychiatric manifestations of primary hyperparathyroidism. Study of 5 cases]. 837 25
Brown tumors also called as osteoclastomas, are rare nonneoplastic lesions that arise in the setting of primary or secondary hyperparathyroidism. Parathyroid adenomas or hyperplasia constitute the major Brown tumor source in
primary hyperparathyroidism
while chronic renal failure is the leading cause in secondary hyperparathyroidism. Most of the patients with the diagnosis of
primary hyperparathyroidism
present with kidney stones or isolated hypercalcemia. However, nearly one third of patients are asymptomatic and hypercalcemia is found incidentally. Skeletal involvement such as generalized osteopenia, bone resorption, bone cysts and Brown tumors are seen on the late phase of hyperparathyroidism. The symptoms include axial pain, radiculopathy,
myelopathy
and myeloradiculopathy according to their locations. Plasmocytoma, lymphoma, giant cell tumors and metastates should be ruled out in the differential diagnosis of Brown tumors. Treatment of Brown tumors involve both the management of hyperparathyroidism and neural decompression. The authors report a very rare spinal Brown tumor case, arisen as the initial manifestation of
primary hyperparathyroidism
that leads to acute paraparesis.
...
PMID:Brown Tumor of the Thoracic Spine: First Manifestation of Primary Hyperparathyroidism. 2658 96
