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Query: UMLS:C0221002 (
primary hyperparathyroidism
)
4,921
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A 9-year-old boy, who had been admitted to the Pediatric Department for the examination of
IgA nephropathy
, was transferred to our urological clinic on Aug. 6, 1985, because of parathyroid crisis. Before urological consultation, he had been complaining of bilateral knee and calcaneal pain, anorexia and abdominal pain, which had persisted for several days. Laboratory data indicated serum Ca of 17.6 mg/dl, iP of 2.3 mg/dl and iPTH of 0.77 ng/ml. Roentgenographic examination such as chest, extremities and neck computed tomography showed no abnormal findings. The final diagnosis was parathyroid crisis caused by
primary hyperparathyroidism
and neck exploration was carried out on August. 10. Left upper parathyroid gland, which was 1 cm in diameter, was surgically removed. The other three glands were normal in size. Histological examination of the resected parathyroid gland revealed chief cell adenoma. In the post-operative course, serum Ca level was soon reduced to the normal range and bone pain disappeared rapidly. During the follow up period of 2.5 years, the patient was clinically free of recurrence. Only 23 cases of
primary hyperparathyroidism
in children have been reported in the Japanese literature. The clinical characteristics of these specific cases are that
primary hyperparathyroidism
in children shows a low incidence of renal lesion, but the complicated bone disease is of higher incidence compared with the adult cases. Histopathologically, parathyroid adenoma was frequently observed (14/19), and the other 5 cases were parathyroid hyperplasia.
...
PMID:[Primary hyperparathyroidism in a child with parathyroid crisis--review of 24 cases reported in Japan]. 266 May 5
We report the first documented case of
IgA nephropathy
occurring after treatment of
primary hyperparathyroidism
. A 29-year-old man with a history of kidney stones and
primary hyperparathyroidism
underwent kidney biopsy for persistent proteinuria and microhematuria 18 months after resection of an ectopic parathyroid adenoma with subsequent normalization of serum calcium and parathyroid hormone levels. On ultrasound, renal intraparenchymal calcifications were noted. Renal biopsy revealed
IgA nephropathy
in addition to tubulointerstitial microcalcifications. The development of
IgA nephropathy
may have been influenced by hyperparathyroidism and/or its treatment. The case highlights the role of renal biopsy in patients with a history of kidney stones and abnormal urinary findings.
...
PMID:IgA nephropathy in a young man with primary hyperparathyroidism. 1567 96
