Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0220723 (
PCA
)
4,687
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
This work evaluates near-infrared (
NIR
) spectroscopy coupled with chemometric tools for determining the superficial content of citral (
S
C
C
t
) on microparticles. To perform this evaluation, using spray drying, citral was encapsulated in a matrix of dextrin using twelve combinations of citral:dextrin ratios (
CDR
) and inlet air temperatures (
IAT
). From each treatment, six samples were extracted, and their
S
C
C
t
and
NIR
absorption spectral profiles were measured. Then, the spectral profiles, pretreated and randomly divided into modeling and validation datasets, were used to build the following prediction models: principal component analysis-multilinear regression (
PCA
-MLR
), principal component analysis-artificial neural network (
PCA
-ANN
), partial least squares regression (
PLSR
) and an artificial neural network (
ANN
). During the validation stage, the models showed
R
2
values from 0.73 to 0.96 and a root mean squared error (
RMSE
) range of [0.061-0.140]. Moreover, when the models were compared, the full and optimized ANN models showed the best fits. According to this study,
NIR
coupled with chemometric tools has the potential for application in determining
S
C
C
t
on microparticles, particularly when using
ANN
models.
...
PMID:Determination of the superficial citral content on microparticles: An application of NIR spectroscopy coupled with chemometric tools. 3138 76
