Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0206061 (
interstitial pneumonia
)
6,105
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The literature is reviewed on patients developing respiratory symptoms while receiving
D-Penicillamine
, most of whom suffered from rheumatoid arthritis. The manifestations were (in decreasing frequency) bronchiolitis obliterans,
interstitial pneumonitis
, a Good pasture's like syndrome and bronchospasm. For each complication we discuss diagnostic criteria, the implication of the drug and the pathogenesis. In addition we make suggestions regarding patients on
D-Penicillamine
and emphasize the need for accurate reporting of adverse pulmonary effects to enlarge the epidemiological picture.
...
PMID:[The respiratory complications of D-Penicillamine therapy (author's transl)]. 704 74
