Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0205700 (ash)
15,125 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In this work, a biologically catalyzed CO₂ mineralization process for the capture of CO₂ from point sources was designed, constructed at a laboratory scale, and, using standard chemical process scale-up protocols, was modeled and evaluated at an industrial scale. A yeast display system in Saccharomyces cerevisae was used to screen several carbonic anhydrase isoforms and mineralization peptides for their impact on CO₂ hydration, CaCO₃ mineralization, and particle settling rate. Enhanced rates for each of these steps in the CaCO₃ mineralization process were confirmed using quantitative techniques in lab-scale measurements. The effect of these enhanced rates on the CO₂ capture cost in an industrial scale CO₂ mineralization process using coal fly ash as the CaO source was evaluated. The model predicts a process using bCA2- yeast and fly ash is ~10% more cost effective per ton of CO₂ captured than a process with no biological molecules, a savings not realized by wild-type yeast and high-temperature stable recombinant CA2 alone or in combination. The levelized cost of electricity for a power plant using this process was calculated and scenarios in which this process compares favorably to CO₂ capture by MEA absorption process are presented.
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PMID:Engineered yeast for enhanced CO₂ mineralization. 2528 21

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