Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0205700 (ash)
 15,125 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a dairy herd of 21 cows which were on pasture during the day at the end of May 2002, four eight years old cows were suddenly inappetent and showed severe diarrhoea consisting of black discolorate feces. A few days after the onset of the disease, three affected cows exhibited neurological disorders. These cows were admitted to the IInd Medical Clinic of the University for Veterinary Medicine in Vienna. Following clinical signs were observed: circulatory weakness, anorexia, atony of the rumen, diarrhoea and in accordance with acute lead poisoning typical signs of the central nervous system. One cow died and the other two animals were euthanized. Results of blood testing were anaemia, basophil spotting of erythrocytes, increase of liver enzymes and CK, hypocalcaemia, decrease of potassium and phosphate. The cerebrospinal fluid of two cows showed increased CK-, LDH- and AST-values. The lead contents of whole blood samples were between 0.486 and 0.928 mg/kg, of liver samples 13.3 to 114.4 mg/kg, of kidney samples 172.2 to 448 mg/kg and of rumen content 59 mg/kg fresh matter. At necropsy, enteritis, liver fluke disease and severe interstitial and alveolar pulmonary emphysema were found. Pathohistologically typical ischaemic necrosis of neurons predominantly at the tips of the gyri, disseminated petechial hemorrhages and moderate diffuse neovascularisation, but no acid-fast intranucleolar inclusion bodies in the renal tubules were observed. As causative agent of the acute lead poisoning a residue on combustion, taken up by the cows on the pasture, was confirmed. The ash residue was formed by combustion of three tires which contained 450 g heavy weights of 96.5% lead for wheel balance. The lead content of the ash residue was between 2.9 and 28 g/kg dry matter.
 ...
PMID:[Acute lead poisoning in cows due to feeding of lead contaminated ash residue]. 1496 24

The effects of chronic exposure to cadmium (Cd) on the mineral status, mechanical properties and incidence of deformities and fractures of the lumbar spine (L1-L5) were studied in a rat model of human exposure. Young female Wistar rats were exposed to 1, 5, 50 or 100 mg Cd/l for 12 months. Cd, dose and time dependently, disturbed the mineral status of the lumbar vertebrae as reflected in decreased bone mineral content (BMC) and density (BMD) at the L1-L5 (DEXA technique) and ash weight (AW) of the fourth lumbar vertebral body (L4). However, the changes were too small to be evident radiographically. Cd had no effect on the ratio of nonorganic to organic component content, except for its decrease at the 100 mg Cd/l. Weakness in the mechanical properties (compression test; Instron machine) of the L4 was noted. At the 1 mg Cd/l, a decrease was observed in the deformation at the yield point, with a simultaneous increase in the L4 stiffness, but not in strength (defined by load at yield or ultimate load). In the 5 mg Cd/l group, similar changes took place and a decrease in the ultimate load was evident as well. At the 50 and 100 mg Cd/l, Cd more seriously affected the L4 mechanical properties. At all levels of Cd exposure, the L4 deformities and/or fractures took place. Intact L4 was noted only in the 1 and 5 mg Cd/l groups. The study clearly revealed that chronic exposure to Cd disturbs the L1-L5 mineral status resulting in weakness in its mechanical properties and in turn in vertebral body (cancellous bone) deformities and fractures. The results allow us to conclude that the critical Cd concentration for these effects is very low [about 0.06-0.09 microg/g dry defatted weight (DW)] and seem to indicate an osteoporotic character of changes. A very important finding of the study is that Cd affects cancellous bone even at low-level intoxication corresponding to the general population exposure. Thus, we hypothesize that environmental exposure to Cd may be a risk factor for the lumbar spine demineralization and increased incidence of vertebral deformities and fractures.
 ...
PMID:Mineral status and mechanical properties of lumbar spine of female rats chronically exposed to various levels of cadmium. 1500 99

In case studies of two herds of dairy cattle, a herd of 270 Friesian cows and heifers and a herd of 256 Jersey cows and heifers experienced high death rates and a protracted course of illness when fly ash was broadcast as a fertiliser over the farms at a rate of about 1 tonne per hectare. The onset of weakness, lassitude and diarrhoea in the cattle first appeared within 4-5 days and both fertility and milk fat production fell off dramatically. In the following 7 months, 51 animals died in the Friesian herd and a similar death rate and performance losses occurred in the Jersey herd. Emaciation and hepatic fibrosis were consistently reported from autopsies. Heavy metal poisoning was eliminated from the possible diagnosis. The slags and fly ash used as fertiliser had several features in common. They contained 29-40% calcium as calcium oxide, 15-35 grams of iron per kg, they were all extremely alkaline and concentrations of lead and arsenic were low. The effect of adding fly ash to rumen contents in vitro was to raise the pH to greater than 7.2, at which point fermentation was markedly-reduced.
 ...
PMID:Fly ash, basic slag and Glenbrook slag toxicity in cattle. 1603 24

Psalmocharias alhageos is an important pest of vine in most parts of Iran, Afghanistan, Pakistan, southern areas of Russia, Turkey and Iraq. This cicada is spread in most provinces in Iran such as Esfahan, Hamedan, Qazvin, Markazi, Lorestan, Qom, Kerman, Tehran and Kordestan. In addition to vine, this insect damages some other fruit trees, such as apple, sour cherry, quince, peach, pomegranate and pear trees and some non-fruit trees, namely white poplar, ash, elm, eglantine, silk and black poplar trees. The nymphs of cicada damage the trees by feeding on root, adult insects on young bud and by oviposition under branch barks. Nourishing root by nymph leads to the weakness of the tree and hinder its growth. The high density oviposition of adult insects inside young barks causes withering of branches. The resulted damage on vine products is 40% which is one of the most important factors in product reduction in vineyard. This research was conducted in Takestan in Qazvin. It was conducted for the first time to study the behaviors of the mates of this vine cicada in order to manage it. Two systems were used to record the sound of male cicada called analog voice-recorder and digital voice recorder. To analyze the recorded sound of the male cicada we used of spectrum analyzer, digital storage oscilloscope and protens 7 computer softwares. We could call the attention of natural enemies an disturb the male insect's attracting sound by producing natural and artificial sound in the range of 1-6 kHz in two different ripeness status of the fruits and could prevent mating and oviposition of female cicadas.
 ...
PMID:The study and analysis of the mating behavior and sound production of male cicada Psalmocharias alhageos (Kol.) (Homoptera:Cicadidae) to make disruption in mating. 1926 19

Clinical efficacy and safety of a herbomineral drug containing withania somnifera Asparagus racemosus glycyrrhiza glabra, mucuna pruriens, Myristica fragrans, Anauchus pyrethrum, Ipomoea digitata, sida cordifolia, zine ash complex and high energy carbohydrate molecules were evaluated in an open study. All patients treated with the drug reported good improvement in the various symptomatology of general weakness appetite, sleep mood, and concentration the overall improvement ranged between 69-77% The drug was well tolerated.
 ...
PMID:Evaluation of the efficacy and safety of a new herbal revitalizer revivin. 2255 91

Rickets can be attributed to nutritional, genetic, hormonal, or toxic disturbances and is classified as a metabolic bone disease. Rickets is most often associated with inappropriate dietary levels of calcium, phosphorus, and/or vitamin D. During a 27-month period (January 2010 through March 2012), the Iowa State University Veterinary Diagnostic Laboratory investigated causes of sudden, unexpected death and lameness in growing pigs throughout the Midwestern United States. Clinical observations from 17 growing pig cases included weakness, lameness, reluctance to move, muscle fasciculations and/or tremors, tetany, and death. Ribs were weak, soft, and bent prior to breaking; rachitic lesions were apparent at costochondral junctions in multiple cases. Acute and/or chronic bone fractures were also noted in multiple bones. Failure of endochondral ossification, expanded physes, infractions, thin trabeculae, and increased osteoclasts were noted microscopically. Decreased bone ash and serum 25(OH)D(3), combined with clinical and microscopic evaluation, confirmed a diagnosis of vitamin D-dependent rickets in all cases. In 3 cases, disease was linked to a specific nutrient supplier that ultimately resulted in a voluntary feed recall; however, most cases in the current investigation were not associated with a particular feed company. The present report describes vitamin D-associated rickets and its importance as a potential cause of weakness, lameness, muscle fasciculations, recumbency or sudden unexpected death in swine, and describes appropriate samples and tests for disease diagnosis.
 ...
PMID:Rickets: case series and diagnostic review of hypovitaminosis D in swine. 2299 90

As a cementitious material, geopolymers show a high quasi-brittle behavior and a relatively low fracture energy. To overcome such a weakness, incorporation of fibers to a brittle matrix is a well-known technique to enhance the flexural properties. This study comprehensively evaluates the short and long term impacts of different volume percentages of polypropylene fiber (PPF) reinforcement on fly ash based geopolymer composites. Different characteristics of the composite were compared at fresh state by flow measurement and hardened state by variation of shrinkage over time to assess the response of composites under flexural and compressive load conditions. The fiber-matrix interface, fiber surface and toughening mechanisms were assessed using field emission scan electron microscopy (FESEM) and atomic force microscopy (AFM). The results show that incorporation of PPF up to 3 wt % into the geopolymer paste reduces the shrinkage and enhances the energy absorption of the composites. While, it might reduce the ultimate flexural and compressive strength of the material depending on fiber content.
...
PMID:A Comprehensive Study of the Polypropylene Fiber Reinforced Fly Ash Based Geopolymer. 2680 25

The relationships between breadmaking quality, kernel properties (physical and chemical), and dough rheology were investigated using flours from six genotypes of Syrian wheat lines, comprising both commercially grown cultivars and advanced breeding lines. Genotypes were grown in 2008/2009 season in irrigated plots in the Eastern part of Syria. Grain samples were evaluated for vitreousness, test weight, 1000-kernel weight and then milled and tested for protein content, ash, and water content. Dough rheology of the samples was studied by the determination of the mixing time, stability, weakness, resistance and the extensibility of the dough. Loaf baking quality was evaluated by the measurement of the specific weight, resilience and firmness in addition to the sensory analysis. A comparative study between the six Syrian wheat genotypes and two English flour samples was conducted. Significant differences were observed among Syrian genotypes in vitreousness (69.3%-95.0%), 1000-kernel weight (35.2-46.9 g) and the test weight (82.2-88.0 kg/hL). All samples exhibited high falling numbers (346 to 417 s for the Syrian samples and 285 and 305 s for the English flours). A significant positive correlation was exhibited between the protein content of the flour and its absorption of water (r = 0.84 **), as well as with the vitreousness of the kernel (r = 0.54 *). Protein content was also correlated with dough stability (r = 0.86 **), extensibility (r = 0.8 **), and negatively correlated with dough weakness (r = -0.69 **). Bread firmness and dough weakness were positively correlated (r = 0.66 **). Sensory analysis indicated Doumah-2 was the best appreciated whilst Doumah 40765 and 46055 were the least appreciated which may suggest their suitability for biscuit preparation rather than bread making.
 ...
PMID:Bread Wheat Quality: Some Physical, Chemical and Rheological Characteristics of Syrian and English Bread Wheat Samples. 2823 87


<< Previous 1 2