Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0205700 (ash)
 15,125 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The results of 2 studies carried out at the Institute of Nutrition of Central American and Panama are described. The 1st study was of an urban population and the other in rural villages. The influences of mode rate maternal malnutrition on the weight of the placenta and its chemical characteristics were particularly studied. Placentas were homogenized and then divided into 3 equal parts which were lyphilized. In the urban study, women of high and of low socioeconomic status were compared. The low socioeconomic group was considered to suffer from calorie deficiency, and particularly protein malnutrition at the time of the study. The values of the tricipital skinfold tests were lower in this group, and the weight for height ratio was low (p less than .01). The average placental weight in the low socioeconomic group was 15% below th at of the high socioeconomic group. Placental concentrations of protein, water, ash, hemoglobin, and DNA were the same in the 2 groups, while hydroxyproline and fat levels were less in the low socioeconomic group, and peripheral villi areas of the placenta were shown to be less in this group (p less than .001). These changes were attributed to moderate maternal malnutrition. In the rural study the female populations of 4 villages were investigated. Mean weight gains during pregnancy were only 60% of normal. Diet consisted mostly of corn and beans with little animal protein. In 2 villages, a dietary supplement containing protein was distributed and in the 2 other villages another supplement without protein and of lower caloric value was given. Placental weights were 11% less in those with the lower caloric and no protein supplement. An association between maternal malnutrition, placental weight, and birth weights of infants was shown. Low placental weight was considered to be the most important measurable factor in reducing birth weights.
 ...
PMID:Effect of moderate maternal malnutrition on the placenta. 80 65