Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0184567 (acute pain)
 3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
EPGN 10.4
TMC3 10.2
regulator of G-protein signaling 9 10.0
TAOK3 9.5
Lutheran glycoprotein 9.3
tolloid-like 2 9.3
KCNJ6 8.8
ST8Sia VI 8.6
NRG4 8.4
KCNJ3 8.2
PPID 8.2
NRG2 8.1
C7 segment 8.0
MST-1 8.0
S1P receptor 3 8.0
PIPP 7.9
PDYN 7.8
opiorphin 7.7
NNT 7.7
hypocretin receptor 2 7.6
NPY2R 7.5
cGKI 7.4
MB-COMT 7.4
P2X4R 7.3
BUP 7.3
orexin receptor-1 7.2
Mu opioid receptor 7.2
ankyrin 1 7.2
Nav1.7 7.2
MHC class II-associated invariant chain 7.2
ARRB2 7.2
TRPM3 7.1
Signal transducer and activator of transcription 1 7.1
NRG3 7.1
Cav3.2 7.1
TRPA1 7.0
NFAT4 7.0
Prodynorphin 7.0
AC8 7.0
HBEGF 6.9
OUT 6.9
ADORA2B 6.8
Tph 6.7
ribosomal S6 protein kinase 6.6
TRPV1 6.6
FPS 6.5
TMEM16B 6.5
TGFA 6.4
Cav3.3 6.4
ASIC 6.4
Kv7.3 6.4
CX3C chemokine receptor 1 6.4
TFL 6.4
P2X4 6.3
KOR 6.3
lysophosphatidic acid receptor 6.3
OX2 6.3
SNS 6.3
TRPM8 6.2
MVD 6.2
GALR2 6.2
sphingosine kinase 2 6.1
V75 6.1
apolipoprotein E receptor 2 6.1
SCO2 6.1
FIZZ1 6.1
TMEM16F 6.1
transient receptor potential vanilloid 1 6.1
USP5 6.1
melastatin 2 6.0
delta opioid receptor 6.0
APS 6.0
ERAS 6.0
BART 6.0
opioid receptor 5.9
mGlu3 5.9
Cav2.2 5.9
mu opioid receptor 5.9
ALDH3A1 5.9
RFT 5.8
more...
Disease
Periarthritis calcarea 13.0
Toxic synovitis 13.0
Chronic pain syndrome 12.0
musculoskeletal neck pain 12.0
Meningococcal arthritis 11.4
Atherosclerotic aneurysm 11.0
Chronic post-thoracotomy pain 11.0
Venous hemangioma 11.0
Phacolytic glaucoma 10.7
Thibierge-Weissenbach syndrome 10.4
Episodic cluster headache 10.4
Thrombosed external hemorrhoids 9.7
Intervertebral disc calcification 9.0
Tendinosis 9.0
Erosive osteoarthritis 8.7
psychogenic pain 8.7
chronic pain 8.7
Cluster C personality disorder 8.6
Milwaukee shoulder 8.6
postherpetic neuralgia 8.5
Milwaukee shoulder 8.5
Acute gouty arthritis 8.4
Medial tibial stress syndrome 8.3
Impacted teeth 8.1
prolapsed hemorrhoids 8.0
cross-dependence 7.9
Orbital pseudotumor 7.8
acute chest syndrome 7.7
Internuclear ophthalmoplegia 7.7
periarthritis 7.6
residual schizophrenia 7.5
external hemorrhoids 7.5
Lymphangiomatosis 7.5
phantom limb pain 7.4
sickle cell crisis 7.4
Acute anterior uveitis 7.4
Hypertrophic pulmonary osteoarthropathy 7.3
chronic appendicitis 7.3
Hemophilic arthropathy 7.3
Neuralgic amyotrophy 7.3
Chronic arthritis 7.2
impaired judgment 7.2
RS3PE syndrome 7.2
recurrent appendicitis 7.2
podagra 7.1
Shoulder impingement syndrome 7.0
calcifying tendinitis 7.0
Spinal epidural hematoma 7.0
Vertebral artery dissection 7.0
acroparesthesia 7.0
Cutaneous vasculitis 6.9
herpes zoster 6.9
back disorder 6.9
Abnormal behavior 6.9
Scott syndrome 6.9
Autotomy 6.8
Opioid dependence 6.7
CCV 6.7
monoarthritis 6.6
HSAN 6.5
Opiates 6.5
lumbar spondylosis 6.5
Parsonage-Turner syndrome 6.5
Testicular torsion 6.4
Opioid use disorder 6.4
strangulated hernia 6.4
Hajdu-Cheney syndrome 6.4
Frey 6.3
Myofascial pain 6.3
sickle cell disease 6.3
Bornholm 6.3
phantom limb 6.3
clostridial infection 6.3
Complex regional pain syndrome 6.2
Achilles tendinitis 6.1
Mesenteric ischemia 6.1
adnexitis 6.1
dry socket 6.1
Freiberg 6.1
physical dependence 6.1
more...
Symptom
acute pain 13.0
Idiopathic scrotal edema 13.0
Cutaneous hyperalgesia 11.4
peritoneal pain 10.7
Activity intolerance 10.4
PAIN 10.2
Sympathetically maintained pain 9.7
Grimace 9.2
Neurogenic pain 9.1
Inflammatory pain 9.1
Labor pain 9.0
musculoskeletal chest pain 9.0
Thoracic pain 8.7
Scrotal pain 8.4
breakthrough pain 8.4
Postoperative pain 8.4
Procedural pain 8.4
Postoperative nausea 8.3
Central pain 8.3
Other pain 8.3
Severe pain 8.2
postpartum pain 8.2
dental pain 8.2
Pain symptoms 8.2
orofacial pain 7.9
swollen scrotum 7.9
cancer pain 7.9
Intractable pain 7.9
acute low back pain 7.9
analgesia 7.7
stump pain 7.7
sinus congestion 7.7
Pain at rest 7.6
musculoskeletal disability 7.4
Kernig's sign 7.4
Neuropathic pain 7.3
Stinging 7.2
chronic back pain 7.2
Murphy's sign 7.0
Postoperative nausea and vomiting 6.9
skin pain 6.7
renal colic 6.6
pain 6.5
jaw pain 6.5
neuralgia 6.4
Blanching 6.3
cardiovascular impairment 6.2
glossodynia 6.2
Visceral pain 6.1
hematocolpos 6.0
facial pain 6.0
limb pain 5.9
Signs and Symptoms 5.9
pneumaturia 5.8
low back pain 5.8
acute abdominal pain 5.7
elbow pain 5.7
scaly skin 5.5
Spastic 5.5
back pain 5.4
hand pain 5.3
Sedation 5.2
dyschezia 5.2
myalgia 5.2
tingling 5.0
sciatica 4.9
athetosis 4.9
nausea and vomiting 4.9
ankle pain 4.9
body pain 4.9
hip pain 4.7
neck pain 4.7
right lower quadrant pain 4.7
knee pain 4.7
constipation 4.7
nausea 4.6
meningism 4.6
bone pain 4.5
shoulder pain 4.5
metatarsalgia 4.5
more...
Drug
Lumiracoxib 11.1
Mobic 10.7
Tapentadol 10.5
Percocet 10.0
Vivitrol 9.5
Parecoxib 9.5
Nefopam hydrochloride 9.1
Zomepirac sodium 9.0
Ketorolac tromethamine 9.0
Elmiron 8.9
Ketorolac 8.7
Indoprofen 8.7
Valdecoxib 8.5
Diclofenac potassium 8.4
Lornoxicam 8.1
Celebrex 8.0
Meclomen 8.0
Pirprofen 7.9
Alvimopan 7.8
Effexor 7.7
Vioxx 7.4
Oxycon 7.4
Ergometrine 7.2
Tiaprofenic acid 7.0
Etodolac 7.0
Levocabastine 7.0
Ketalar 7.0
Keppra 6.9
Chymopapain 6.8
Rizatriptan 6.8
Fentanyl 6.5
Ketalar 6.4
Nabumetone 6.4
Pregabalin 6.2
Gabapentin 6.2
FCV 6.1
Dipyrone 6.1
Proglumide 6.1
Reboxetine 6.0
Tenoxicam 6.0
Bupivacaine 6.0
Maalox 6.0
Enoximone 5.9
GHRP 5.8
Vinpocetine 5.8
Nimesulide 5.7
Ibandronate 5.7
Zileuton 5.7
Duloxetine 5.7
Rasagiline 5.7
Atipamezole 5.6
BOTOX 5.6
Codeine 5.6
Butorphanol 5.5
Salmon calcitonin 5.5
APM 5.5
Codeine 5.5
SNL 5.5
Emodin 5.4
Medetomidine 5.3
Cytidine 5.1
Sodium alginate 5.1
Escitalopram 5.0
Arthrex 5.0
Meconium 4.6
Domperidone 4.6
Triad 4.6
9-THC 4.2
Hyaluronidase 4.1
Hyaluronidase 4.0
Zoledronic acid 4.0
Acyclovir 3.9
BTC 3.8
IL-1ra 3.6
Camp 3.5
OTC 3.5
MgSO4 3.4
Zoledronic acid 3.3
Clonidine 3.3
BoNT/A 3.2
more...
Enzyme
FPS 6.5
D-aspartate oxidase 6.4
SRR 5.9
IOR 5.7
GD3 synthase 5.4
SOR 5.0
catechol O-methyltransferase 4.4
CPN 4.2
cathepsin S 4.0
factor C 3.7
monoacylglycerol lipase 3.6
SOR 3.5
PST 3.3
PKG 3.3
GRK2 3.2
tryptophan hydroxylase 3.2
ALDH 3.2
botulinum neurotoxin 3.1
glutaminase 3.1
GRK5 2.8
TSA 2.7
CPS 2.7
heme oxygenase 2.5
dopamine beta-hydroxylase 2.5
transpeptidase 2.5
histidine decarboxylase 2.5
PTA 2.2
guanylate cyclase 2.2
alpha-galactosidase 2.2
ornithine transcarbamylase 2.2
prostate-specific membrane antigen 2.2
PCP 2.1
PRE 2.1
phosphodiesterase 1.9
lactase 1.9
soluble epoxide hydrolase 1.9
MDP 1.6
AMPK 1.4
CYP3A4 1.3
CPT 1.3
protein kinase C 1.3
aldolase 1.2
CPT 1.2
creatine kinase 1.1
NADPH-diaphorase 1.0
lipoxygenase 0.9
AMP-activated protein kinase 0.9
aldehyde dehydrogenase 0.9
aldehyde dehydrogenase 0.9
aldehyde dehydrogenase 0.9
CPT 0.8
hyaluronidase 0.8
phospholipase C 0.8
transcriptase 0.8
protein kinase 0.7
DNA methyltransferase 0.7
aldehyde dehydrogenase 0.6
NO synthase 0.6
monoamine oxidase 0.6
aspartate aminotransferase 0.6
focal adhesion kinase 0.5
calcineurin 0.5
hyaluronidase 0.4
AMPK 0.4
caspase-1 0.4
adenylate cyclase 0.3
aldehyde dehydrogenase 0.3
GSK 0.2
prostate-specific antigen 0.2
urease 0.1
beta-galactosidase 0.1
tyrosine hydroxylase 0.1
MAP 0.1
urease 0.1
ERK -0.1
MEK -0.2
lipase -0.2
lactate dehydrogenase -0.3
CD10 -0.3
mitogen-activated protein kinase -0.4
more...
Compound
C15H26O 11.4
6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol 10.7
(+)-Borneol 10.5
Etoricoxib 9.5
Meclofenamate sodium 9.0
Rofecoxib 8.9
Ketorolac 8.9
Hydromorphone 8.6
DETP 8.3
Hydrocodone 8.3
Kyotorphin 8.3
Carprofen 8.0
Suprofen 8.0
Tramadol 7.9
Azapropazone 7.8
Oxycodone 7.8
Meloxicam 7.8
Bixin 7.7
Bixin 7.7
Linopirdine 7.7
Resiniferatoxin 7.6
Etidocaine 7.4
Nalbuphine 7.3
Phenylethanolamine 7.2
Endomorphin-1 7.2
Meperidine 7.2
Chlorzoxazone 7.1
DGI 7.1
Cyanocobalamin 7.0
Celecoxib 6.9
Pentazocine 6.8
CONV 6.8
Mepivacaine 6.8
Methoxyflurane 6.7
DHbetaE 6.7
Pentazocine 6.6
Sooner 6.5
Remifentanil 6.5
(S)-4-carboxyphenylglycine 6.4
NOP 6.4
Dextromethorphan 6.2
Buprenorphine 6.2
Ketamine 6.2
Alfentanil 6.1
Epibatidine 6.0
Ibuprofen 6.0
Ketoprofen 6.0
Retigabine 6.0
Bupivacaine 6.0
Morphine 6.0
Silver sulfadiazine 6.0
Allyl isothiocyanate 5.9
DXP 5.8
Salvinorin A 5.8
Ergonovine 5.8
HBB 5.8
Esculetin 5.7
Meclofenamate 5.7
Methadone 5.6
Butorphanol 5.6
APAP 5.6
Fluvoxamine 5.6
Codeine 5.5
Diclofenac 5.5
Sufentanil 5.5
Esmolol 5.4
Carrageenan 5.4
propionamide 5.4
propionamide 5.3
Agmatine 5.3
AEA 5.3
APS 5.2
GBL 5.2
Amitriptyline 5.2
Acetyl-L-carnitine 5.2
Foscarnet 5.2
hydroxyethylamine 5.2
1,2,3,6-tetrahydropyridine 5.1
DAMGO 5.1
1,2,3,6-tetrahydropyridine 5.1
more...