Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0184567 (acute pain)
3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 253
opioid receptor 84
COX-2 53
Mol 51
cyclooxygenase-2 42
She 38
substance P 36
cyclooxygenase 35
TRPV1 34
MRI 33
hemoglobin 28
PCA 24
GABA 24
cytokine 22
calcitonin 22
COX-1 22
NMDA receptor 22
TRPA1 18
TNF 17
beta-endorphin 16
ATP 16
bradykinin 16
cannabinoid receptor 15
transient receptor potential vanilloid 1 15
ASA 13
reserved 13
CB1 12
nitric oxide synthase 11
axonal 11
calcium channel 11
CFA 11
APS 10
COX 10
sodium channel 9
TLR4 9
ankylosing spondylitis 9
phosphodiesterase 9
arrestin 9
IL-6 9
mu opioid receptor 9
OFQ 8
SNS 8
neurotensin 8
collagen 8
ankyrin 1 8
CSF 8
brain-derived neurotrophic factor 8
corticotropin-releasing factor 8
P2X 8
lipopolysaccharide 8
IL-1 7
p38 7
SII 7
IL-10 7
Pol 7
rat) 7
delta opioid receptor 7
insulin 7
DRG 7
CB2 7
cyclooxygenase 2 7
proenkephalin 6
NNT 6
P2X4 6
ERK 6
ANOVA 6
olfactory 6
TRPM8 6
tumor necrosis factor 6
interferon 6
c-fos 6
Nav1.7 6
somatostatin 6
5-hydroxytryptamine 6
interleukin-6 6
CD4 5
C-reactive protein 5
cage 5
L-type calcium channel 5
anonymous 5
more...
Disease
chronic pain 973
cancer 184
depression 173
sickle cell disease 113
cold 112
osteoarthritis 91
addiction 84
herpes zoster 76
postherpetic neuralgia 70
arthritis 69
rheumatoid arthritis 61
tumor 55
migraine 48
pruritus 45
rash 41
osteoporosis 33
ischemia 32
stroke 32
fibromyalgia 29
diabetes 27
Frey 26
hypertension 25
PCA 24
peripheral neuropathy 23
varicella 23
cognitive impairment 21
neuropathy 21
Best 19
hernia 18
breast cancer 17
multiple sclerosis 16
acute chest syndrome 15
fits 15
emotional distress 14
physical dependence 14
trigeminal neuralgia 14
renal failure 13
diabetic neuropathy 12
gout 12
phantom limb pain 12
deep vein thrombosis 12
delirium 12
confusion 12
NAME 12
anemia 11
posttraumatic stress disorder 11
acute appendicitis 11
appendicitis 11
PGA 11
aggression 11
pneumonia 11
drug addiction 10
haemophilia 10
obesity 10
asthma 10
HIV 10
tendinitis 10
Alzheimer's disease 9
carcinoma 9
gallstones 9
mental illness 9
Infection 9
myocardial infarction 9
substance abuse 9
synovitis 9
West 9
ankylosing spondylitis 9
infectious diseases 8
scrotum 8
psychological stress 8
Toxic epidermal necrolysis 8
inguinal hernia 8
psychological distress 8
genetic disorder 8
arthropathy 8
thalassemia 8
rheumatism 8
compartment syndrome 7
heart failure 7
emotional stress 7
more...
Symptom
acute pain 3962
pain 2978
analgesia 727
anesthesia 254
headache 105
cancer pain 92
nausea 71
low back pain 69
back pain 64
vomiting 63
Postoperative pain 46
dental pain 44
discomfort 41
abdominal pain 41
discomfort 38
nausea and vomiting 36
constipation 32
myalgia 29
orofacial pain 29
Neuropathic pain 27
weakness 24
distraction 24
dizziness 23
fatigue 22
facial pain 19
breakthrough pain 18
arthralgia 18
neuralgia 18
sleepiness 16
cough 15
erythema 15
seizures 14
chronic back pain 14
dyspnea 13
acute abdominal pain 13
neck pain 13
diarrhea 12
chest pain 12
paresthesia 11
pelvic pain 10
acute stress 10
renal colic 10
PAIN 10
spasm 10
collapse 10
bone pain 9
knee pain 9
agitation 9
acute low back pain 8
functional recovery 8
shoulder pain 8
numbness 8
hypothermia 7
angina 7
acute abdomen 7
colic 6
Sedation 6
Severe pain 6
sciatica 6
hip pain 6
tingling 5
Inflammatory pain 5
limb pain 5
Grimace 5
insomnia 5
splenomegaly 5
leg pain 4
pallor 4
paresis 4
tremor 4
Postoperative nausea and vomiting 4
stigma 4
enuresis 3
Ill 3
anorexia 3
spasticity 3
overweight 3
ataxia 3
stump pain 3
sore throat 3
more...
Drug
Tapentadol 20
Dermatol 16
Ketorolac 15
Fentanyl 14
Lumiracoxib 13
Cardiovasc 9
Gabapentin 8
CSF 8
caffeine 7
Ketorolac tromethamine 7
Bupivacaine 6
lysine 6
Monit 5
Parecoxib 5
nitroglycerin 5
Celebrex 4
Valdecoxib 4
GHRP 4
Pregabalin 4
9-THC 4
Clonidine 3
Emodin 3
ENT 3
Vioxx 3
EE2 2
Indomethacin 2
Award 2
Capsicum 2
Duloxetine 2
Etodolac 2
Heme 2
lactose 2
MgSO4 2
Percocet 2
Nimesulide 2
Domperidone 2
IL-1ra 2
PCP 2
Indoprofen 2
ICI 2
ROC 2
Codeine 2
FCV 2
Lornoxicam 2
Acyclovir 2
Triad 2
Mobic 2
Codeine 2
VCR 1
Zileuton 1
Meclomen 1
Nephron 1
Zoledronic acid 1
BH4 1
pyridoxal phosphate 1
Rizatriptan 1
Sorafenib 1
BTC 1
PFA 1
Nabumetone 1
APM 1
MAP 1
L-tyrosine 1
DPA 1
Proglumide 1
BOTOX 1
DEX 1
OTC 1
Asthma 1
Vinpocetine 1
Propofol 1
Horizon 1
Tenoxicam 1
Cytidine 1
CAM 1
Reboxetine 1
Ibandronate 1
Oxycon 1
Zoledronic acid 1
Tiaprofenic acid 1
more...
Enzyme
protein kinase 17
protein kinase C 15
ERK 11
phosphodiesterase 9
mitogen-activated protein kinase 9
focal adhesion kinase 8
creatine kinase 5
guanylate cyclase 5
phospholipase C 4
ACS 4
FPS 4
aspartate aminotransferase 4
NO synthase 3
lactate dehydrogenase 3
calcineurin 3
PKG 3
adenylate cyclase 3
AMP-activated protein kinase 3
catalase 3
peroxidase 3
heme oxygenase 3
monoamine oxidase 2
transcriptase 2
PCP 2
caspase-3 2
MEK 2
lipase 2
tyrosine hydroxylase 2
AMPK 2
AMPK 2
glutaminase 2
RNA polymerase 2
CYP3A4 2
beta-galactosidase 2
superoxide dismutase 2
thrombin 2
botulinum neurotoxin 2
lipoxygenase 2
tryptophan hydroxylase 2
ATPase 2
tissue plasminogen activator 1
NADPH-diaphorase 1
aldehyde dehydrogenase 1
urokinase-type plasminogen activator 1
CPT 1
prostate-specific membrane antigen 1
prostate-specific antigen 1
ALDH 1
hyaluronidase 1
factor C 1
aldolase 1
D-aspartate oxidase 1
histidine decarboxylase 1
hyaluronidase 1
soluble epoxide hydrolase 1
GRK2 1
GRK5 1
alkaline phosphatase 1
urease 1
alanine aminotransferase 1
GSK 1
renin 1
dopamine beta-hydroxylase 1
SOR 1
chymotrypsin 1
PRE 1
CD10 1
CPN 1
PST 1
ornithine transcarbamylase 1
caspase-1 1
transpeptidase 1
SOR 1
TSA 1
P-glycoprotein 1
alpha-galactosidase 1
ACE 1
catechol O-methyltransferase 1
trypsin 1
aldehyde dehydrogenase 1
more...
Compound
Clin 340
Dec 271
calcium 65
oxygen 60
sodium 59
water 46
glutamate 42
Morphine 40
APAP 32
acetic acid 29
NMDA 27
GABA 24
potassium 24
nitric oxide 24
GABA 24
Tramadol 21
Ketamine 21
ASA 19
arginine 17
TNF 17
noradrenaline 16
ATP 16
glucose 15
5-HT 15
Ketorolac 15
Celecoxib 14
Ibuprofen 14
cysteine 12
lysine 12
tyrosine 12
ethanol 11
Rofecoxib 11
DNA 11
Optimal 10
His 10
COX 10
Naloxone 10
APS 10
CO2 9
methionine 9
cGMP 9
Meloxicam 9
PGE2 9
iron 9
Etoricoxib 9
leucine 8
PGE 8
sulfate 8
phosphate 8
Methadone 8
HCl 8
Buprenorphine 8
caffeine 8
Paclitaxel 7
salt 7
Lidocaine 7
Gly 7
6-12 7
Oxycodone 7
Bupivacaine 6
Phe 6
Capsaicin 6
formaldehyde 6
Meperidine 6
AMPA 6
urea 6
Diclofenac 6
Glutamate 6
DAMGO 6
nitrogen 6
cAMP 6
NH2 6
Neuronal 5
HBB 5
gamma-aminobutyric acid 5
PEG 5
propionic acid 5
glycerol 5
hydroxide 5
phenol 5
more...