Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0184567 (
acute pain
)
3,962
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
253
opioid receptor
84
COX-2
53
Mol
51
cyclooxygenase-2
42
She
38
substance P
36
cyclooxygenase
35
TRPV1
34
MRI
33
hemoglobin
28
PCA
24
GABA
24
cytokine
22
calcitonin
22
COX-1
22
NMDA receptor
22
TRPA1
18
TNF
17
beta-endorphin
16
ATP
16
bradykinin
16
cannabinoid receptor
15
transient receptor potential vanilloid 1
15
ASA
13
reserved
13
CB1
12
nitric oxide synthase
11
axonal
11
calcium channel
11
CFA
11
APS
10
COX
10
sodium channel
9
TLR4
9
ankylosing spondylitis
9
phosphodiesterase
9
arrestin
9
IL-6
9
mu opioid receptor
9
OFQ
8
SNS
8
neurotensin
8
collagen
8
ankyrin 1
8
CSF
8
brain-derived neurotrophic factor
8
corticotropin-releasing factor
8
P2X
8
lipopolysaccharide
8
IL-1
7
p38
7
SII
7
IL-10
7
Pol
7
rat)
7
delta opioid receptor
7
insulin
7
DRG
7
CB2
7
cyclooxygenase 2
7
proenkephalin
6
NNT
6
P2X4
6
ERK
6
ANOVA
6
olfactory
6
TRPM8
6
tumor necrosis factor
6
interferon
6
c-fos
6
Nav1.7
6
somatostatin
6
5-hydroxytryptamine
6
interleukin-6
6
CD4
5
C-reactive protein
5
cage
5
L-type calcium channel
5
anonymous
5
more...
Disease
chronic pain
973
cancer
184
depression
173
sickle cell disease
113
cold
112
osteoarthritis
91
addiction
84
herpes zoster
76
postherpetic neuralgia
70
arthritis
69
rheumatoid arthritis
61
tumor
55
migraine
48
pruritus
45
rash
41
osteoporosis
33
ischemia
32
stroke
32
fibromyalgia
29
diabetes
27
Frey
26
hypertension
25
PCA
24
peripheral neuropathy
23
varicella
23
cognitive impairment
21
neuropathy
21
Best
19
hernia
18
breast cancer
17
multiple sclerosis
16
acute chest syndrome
15
fits
15
emotional distress
14
physical dependence
14
trigeminal neuralgia
14
renal failure
13
diabetic neuropathy
12
gout
12
phantom limb pain
12
deep vein thrombosis
12
delirium
12
confusion
12
NAME
12
anemia
11
posttraumatic stress disorder
11
acute appendicitis
11
appendicitis
11
PGA
11
aggression
11
pneumonia
11
drug addiction
10
haemophilia
10
obesity
10
asthma
10
HIV
10
tendinitis
10
Alzheimer's disease
9
carcinoma
9
gallstones
9
mental illness
9
Infection
9
myocardial infarction
9
substance abuse
9
synovitis
9
West
9
ankylosing spondylitis
9
infectious diseases
8
scrotum
8
psychological stress
8
Toxic epidermal necrolysis
8
inguinal hernia
8
psychological distress
8
genetic disorder
8
arthropathy
8
thalassemia
8
rheumatism
8
compartment syndrome
7
heart failure
7
emotional stress
7
more...
Symptom
acute pain
3962
pain
2978
analgesia
727
anesthesia
254
headache
105
cancer pain
92
nausea
71
low back pain
69
back pain
64
vomiting
63
Postoperative pain
46
dental pain
44
discomfort
41
abdominal pain
41
discomfort
38
nausea and vomiting
36
constipation
32
myalgia
29
orofacial pain
29
Neuropathic pain
27
weakness
24
distraction
24
dizziness
23
fatigue
22
facial pain
19
breakthrough pain
18
arthralgia
18
neuralgia
18
sleepiness
16
cough
15
erythema
15
seizures
14
chronic back pain
14
dyspnea
13
acute abdominal pain
13
neck pain
13
diarrhea
12
chest pain
12
paresthesia
11
pelvic pain
10
acute stress
10
renal colic
10
PAIN
10
spasm
10
collapse
10
bone pain
9
knee pain
9
agitation
9
acute low back pain
8
functional recovery
8
shoulder pain
8
numbness
8
hypothermia
7
angina
7
acute abdomen
7
colic
6
Sedation
6
Severe pain
6
sciatica
6
hip pain
6
tingling
5
Inflammatory pain
5
limb pain
5
Grimace
5
insomnia
5
splenomegaly
5
leg pain
4
pallor
4
paresis
4
tremor
4
Postoperative nausea and vomiting
4
stigma
4
enuresis
3
Ill
3
anorexia
3
spasticity
3
overweight
3
ataxia
3
stump pain
3
sore throat
3
more...
Drug
Tapentadol
20
Dermatol
16
Ketorolac
15
Fentanyl
14
Lumiracoxib
13
Cardiovasc
9
Gabapentin
8
CSF
8
caffeine
7
Ketorolac tromethamine
7
Bupivacaine
6
lysine
6
Monit
5
Parecoxib
5
nitroglycerin
5
Celebrex
4
Valdecoxib
4
GHRP
4
Pregabalin
4
9-THC
4
Clonidine
3
Emodin
3
ENT
3
Vioxx
3
EE2
2
Indomethacin
2
Award
2
Capsicum
2
Duloxetine
2
Etodolac
2
Heme
2
lactose
2
MgSO4
2
Percocet
2
Nimesulide
2
Domperidone
2
IL-1ra
2
PCP
2
Indoprofen
2
ICI
2
ROC
2
Codeine
2
FCV
2
Lornoxicam
2
Acyclovir
2
Triad
2
Mobic
2
Codeine
2
VCR
1
Zileuton
1
Meclomen
1
Nephron
1
Zoledronic acid
1
BH4
1
pyridoxal phosphate
1
Rizatriptan
1
Sorafenib
1
BTC
1
PFA
1
Nabumetone
1
APM
1
MAP
1
L-tyrosine
1
DPA
1
Proglumide
1
BOTOX
1
DEX
1
OTC
1
Asthma
1
Vinpocetine
1
Propofol
1
Horizon
1
Tenoxicam
1
Cytidine
1
CAM
1
Reboxetine
1
Ibandronate
1
Oxycon
1
Zoledronic acid
1
Tiaprofenic acid
1
more...
Enzyme
protein kinase
17
protein kinase C
15
ERK
11
phosphodiesterase
9
mitogen-activated protein kinase
9
focal adhesion kinase
8
creatine kinase
5
guanylate cyclase
5
phospholipase C
4
ACS
4
FPS
4
aspartate aminotransferase
4
NO synthase
3
lactate dehydrogenase
3
calcineurin
3
PKG
3
adenylate cyclase
3
AMP-activated protein kinase
3
catalase
3
peroxidase
3
heme oxygenase
3
monoamine oxidase
2
transcriptase
2
PCP
2
caspase-3
2
MEK
2
lipase
2
tyrosine hydroxylase
2
AMPK
2
AMPK
2
glutaminase
2
RNA polymerase
2
CYP3A4
2
beta-galactosidase
2
superoxide dismutase
2
thrombin
2
botulinum neurotoxin
2
lipoxygenase
2
tryptophan hydroxylase
2
ATPase
2
tissue plasminogen activator
1
NADPH-diaphorase
1
aldehyde dehydrogenase
1
urokinase-type plasminogen activator
1
CPT
1
prostate-specific membrane antigen
1
prostate-specific antigen
1
ALDH
1
hyaluronidase
1
factor C
1
aldolase
1
D-aspartate oxidase
1
histidine decarboxylase
1
hyaluronidase
1
soluble epoxide hydrolase
1
GRK2
1
GRK5
1
alkaline phosphatase
1
urease
1
alanine aminotransferase
1
GSK
1
renin
1
dopamine beta-hydroxylase
1
SOR
1
chymotrypsin
1
PRE
1
CD10
1
CPN
1
PST
1
ornithine transcarbamylase
1
caspase-1
1
transpeptidase
1
SOR
1
TSA
1
P-glycoprotein
1
alpha-galactosidase
1
ACE
1
catechol O-methyltransferase
1
trypsin
1
aldehyde dehydrogenase
1
more...
Compound
Clin
340
Dec
271
calcium
65
oxygen
60
sodium
59
water
46
glutamate
42
Morphine
40
APAP
32
acetic acid
29
NMDA
27
GABA
24
potassium
24
nitric oxide
24
GABA
24
Tramadol
21
Ketamine
21
ASA
19
arginine
17
TNF
17
noradrenaline
16
ATP
16
glucose
15
5-HT
15
Ketorolac
15
Celecoxib
14
Ibuprofen
14
cysteine
12
lysine
12
tyrosine
12
ethanol
11
Rofecoxib
11
DNA
11
Optimal
10
His
10
COX
10
Naloxone
10
APS
10
CO2
9
methionine
9
cGMP
9
Meloxicam
9
PGE2
9
iron
9
Etoricoxib
9
leucine
8
PGE
8
sulfate
8
phosphate
8
Methadone
8
HCl
8
Buprenorphine
8
caffeine
8
Paclitaxel
7
salt
7
Lidocaine
7
Gly
7
6-12
7
Oxycodone
7
Bupivacaine
6
Phe
6
Capsaicin
6
formaldehyde
6
Meperidine
6
AMPA
6
urea
6
Diclofenac
6
Glutamate
6
DAMGO
6
nitrogen
6
cAMP
6
NH2
6
Neuronal
5
HBB
5
gamma-aminobutyric acid
5
PEG
5
propionic acid
5
glycerol
5
hydroxide
5
phenol
5
more...