Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0184567 (acute pain)
3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 253
opioid receptor 84
COX-2 53
Mol 51
cyclooxygenase-2 42
She 38
substance P 36
cyclooxygenase 35
TRPV1 34
MRI 33
hemoglobin 28
PCA 24
GABA 24
NMDA receptor 22
COX-1 22
cytokine 22
calcitonin 22
TRPA1 18
TNF 17
beta-endorphin 16
ATP 16
bradykinin 16
cannabinoid receptor 15
transient receptor potential vanilloid 1 15
reserved 13
ASA 13
CB1 12
axonal 11
CFA 11
nitric oxide synthase 11
calcium channel 11
APS 10
COX 10
TLR4 9
IL-6 9
arrestin 9
ankylosing spondylitis 9
phosphodiesterase 9
mu opioid receptor 9
sodium channel 9
more...
Disease
chronic pain 973
cancer 184
depression 173
sickle cell disease 113
cold 112
osteoarthritis 91
addiction 84
herpes zoster 76
postherpetic neuralgia 70
arthritis 69
rheumatoid arthritis 61
tumor 55
migraine 48
pruritus 45
rash 41
osteoporosis 33
stroke 32
ischemia 32
fibromyalgia 29
diabetes 27
Frey 26
hypertension 25
PCA 24
varicella 23
peripheral neuropathy 23
cognitive impairment 21
neuropathy 21
Best 19
hernia 18
breast cancer 17
multiple sclerosis 16
acute chest syndrome 15
fits 15
physical dependence 14
trigeminal neuralgia 14
emotional distress 14
renal failure 13
confusion 12
delirium 12
deep vein thrombosis 12
more...
Symptom
acute pain 3962
pain 2978
analgesia 727
anesthesia 254
headache 105
cancer pain 92
nausea 71
low back pain 69
back pain 64
vomiting 63
Postoperative pain 46
dental pain 44
abdominal pain 41
discomfort 41
discomfort 38
nausea and vomiting 36
constipation 32
myalgia 29
orofacial pain 29
Neuropathic pain 27
weakness 24
distraction 24
dizziness 23
fatigue 22
facial pain 19
arthralgia 18
neuralgia 18
breakthrough pain 18
sleepiness 16
erythema 15
cough 15
seizures 14
chronic back pain 14
neck pain 13
dyspnea 13
acute abdominal pain 13
diarrhea 12
chest pain 12
paresthesia 11
spasm 10
more...
Drug
Tapentadol 20
Dermatol 16
Ketorolac 15
Fentanyl 14
Lumiracoxib 13
Cardiovasc 9
CSF 8
Gabapentin 8
Ketorolac tromethamine 7
caffeine 7
Bupivacaine 6
lysine 6
Monit 5
Parecoxib 5
nitroglycerin 5
9-THC 4
Pregabalin 4
Valdecoxib 4
Celebrex 4
GHRP 4
Clonidine 3
Vioxx 3
Emodin 3
ENT 3
lactose 2
Award 2
Indomethacin 2
ICI 2
Codeine 2
Lornoxicam 2
Capsicum 2
Duloxetine 2
Mobic 2
Percocet 2
Nimesulide 2
Domperidone 2
Indoprofen 2
Etodolac 2
Triad 2
ROC 2
more...
Enzyme
protein kinase 17
protein kinase C 15
ERK 11
mitogen-activated protein kinase 9
phosphodiesterase 9
focal adhesion kinase 8
creatine kinase 5
guanylate cyclase 5
aspartate aminotransferase 4
ACS 4
FPS 4
phospholipase C 4
AMP-activated protein kinase 3
peroxidase 3
PKG 3
heme oxygenase 3
NO synthase 3
adenylate cyclase 3
calcineurin 3
lactate dehydrogenase 3
catalase 3
transcriptase 2
lipoxygenase 2
monoamine oxidase 2
AMPK 2
glutaminase 2
caspase-3 2
CYP3A4 2
lipase 2
tyrosine hydroxylase 2
thrombin 2
MEK 2
botulinum neurotoxin 2
beta-galactosidase 2
superoxide dismutase 2
RNA polymerase 2
PCP 2
AMPK 2
tryptophan hydroxylase 2
ATPase 2
more...
Compound
Clin 340
Dec 271
calcium 65
oxygen 60
sodium 59
water 46
glutamate 42
Morphine 40
APAP 32
acetic acid 29
NMDA 27
GABA 24
potassium 24
nitric oxide 24
GABA 24
Ketamine 21
Tramadol 21
ASA 19
TNF 17
arginine 17
noradrenaline 16
ATP 16
Ketorolac 15
5-HT 15
glucose 15
Celecoxib 14
Ibuprofen 14
lysine 12
tyrosine 12
cysteine 12
DNA 11
ethanol 11
Rofecoxib 11
Naloxone 10
Optimal 10
APS 10
COX 10
His 10
methionine 9
Meloxicam 9
more...