Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0184567 (acute pain)
 3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 33 years old male patient was admitted at the Ginecology/Obstetric emergency room with acute pain abdomen. The patient underwent an exploratory laparotomy where it was found 1,400 cc of blood in the peritoneal cavity. It was also found a 10 cm diameter tumor on the right lateral uterus side involving the uterine tube, the ovary and the ipsilateral parametrium. In the omentum there were found two 3 cm diameter tumors like the one found in the uterus. The bleeding was under control so it was made a hysterectomy, bilateral salpingooophorectomy and omentectomy. Histopathologic diagnosis was reported two weeks after. The final diagnosis was serosa infiltration, uterine leiomyosarcoma and implant on peritoneum.
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PMID:[Uterine leiomyosarcoma. A report of a case]. 1584 49

Gastrointestinal stromal tumors are the most common mesenchymal tumors of the gastrointestinal tract. These tumors are present in almost all case mutations of KIT-CD117. When located in different places other than the gastrointestinal tract they are called extragastrointestinal stromal tumors (EGISTs). We present the case of a 70-year old patient with abdominal pain. Computed tomography (C/T) and ultrasound (U/S) indicated the existence of a hypoechoic enlarged 9.6 x 10 cm uterus due to leiomyoma. The clinical condition of the patient deteriorated and obtained the characteristics of an acute abdomen. The patient underwent urgent exploratory laparotomy, which revealed the incidental existence of a large tumorous formation in the pouch of Douglas. A total abdominal hysterectomy, bilateral ovarectomy, omentectomy, and tumor resection from the rectouterine pouch were performed. Histology analysis confirmed the diagnosis of a malignant EGIST. EGISTs are infrequent in pelvis. In our case, pelvic EGIST led to an acute pain symptomatology obtaining characteristics of invasive uterine leiomyosarcoma. Pelvic imaging with classical methods of U/S and C/T may lead to confusion and false diagnosis. To the best of our knowledge, this is the first case report about an EGIST located in the rectouterine pouch of Douglas leading to acute abdomen symptomatology.
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PMID:Extragastrointestinal stromal tumor mimicking a uterine tumor. A rare clinical entity. 1798 44