Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0184567 (acute pain)
3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This paper reviews the use of tramadol in the management of acute pain. Tramadol is a weak opioid analgesic with a potency comparable to that of pethidine. While it is not recommended as a supplement to general anaesthesia because of its insufficient sedative activity, tramadol has been successful in the treatment of postoperative pain. Several studies have demonstrated its analgesic efficacy after intramuscular and intravenous application, both in adults and children. Moreover, negligible respiratory depressant activity and only minor side effects have consistently been shown. Patient-controlled analgesia with tramadol has been frequently employed and was well accepted by the patients. There have been only a few studies of oral or spinal application of tramadol in acute pain states. Tramadol has also been used for the control of pain associated with labour and acute myocardial infarction, as well as for the management of trauma pain. In summary, tramadol can be recommended as a basic analgesic for the treatment of patients with moderate to severe pain.
...
PMID:Tramadol for the management of acute pain. 751 22

Pain is a multi-dimensional phenomenon unique to each individual. Most of the research to date on acute pain has focused on oncology, medical and surgical patients. This pilot study was designed to explore the issues of pain assessment by patients and nurses in acute myocardial infarction, and the nurses' subsequent documentation of the pain assessment. Three research instruments were chosen to elicit the information required: A demographic questionnaire was constructed to elicit relevant data on patients and nurses. The Short Form McGill Pain Questionnaire (SFMPQ) was used to measure the quality and quantity of the patient's pain as perceived by the patient and nurse in a myocardial infarction situation. The Chart Audit Information Form (CAIF) was chosen to extract specific information from the nursing notes on the pain experience as recorded by the nurse. A convenience sample of patients comprised 10 males and 5 females. The nursing population comprised a convenience sample of 8 registered nurses holding a recognised coronary care course certificate. The pilot study was conducted in a coronary care unit (CCU) in a large teaching hospital in Dublin, Ireland. The data generated from the SFMPQ and the CAIF were coded prior to computerisation. Descriptive statistics were used to analyse the data. The findings of this pilot study indicated that nurses underestimated the patient's pain in 46% of myocardial infarction situations and overestimated in 13% of them. Furthermore, results indicated that while the majority of nurses documented location and verbal statements of pain, the documentation of quality, intensity and duration of pain was inadequate.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:Pain assessment by patients and nurses, and nurses' notes on it, in early acute myocardial infarction. Part I. 767 Feb 85

Reversible stress-induced cardiomyopathy, i.e., Takotsubo cardiomyopathy, rarely presents in preoperative patients. We provide the case reports of two patients who presented with Takotsubo cardiomyopathy, which we surmise was due to excess endogenous catecholamine production in response to acute pain. Electrocardiogram revealed T-wave inversion, with peak Troponin-T elevation in each case, i.e., 0.66 microg/L and 0.14 microg/L (normal range <0.03 microg/L). Despite these findings consistent with acute myocardial infarction, neither patient had obstructive coronary disease at angiography. Left ventriculography showed apical ballooning, a typical feature of the Takotsubo syndrome. Ventricular dysfunction had resolved completely at repeat echocardiography 2 wk later, after adequate analgesia and surgery.
...
PMID:Takotsubo cardiomyopathy in two preoperative patients with pain. 2018 48