Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0184567 (acute pain)
 3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Orbital myositis (OM) is defined as a nonspecific localized orbital inflammatory process in which one or more of the extraocular muscles are involved. Clinically, it is characterized by acute pain exacerbated by eye movements. Diagnosis is based on history, clinical manifestations, and therapeutic response to steroids. Histologically, OM is characterized by polymorphous infiltration of inflammatory cells and varying amounts of fibrosis. Pathogenesis is unknown, but is probably related to underlying immune-mediated processes. Various inflammatory diseases have been associated with OM, and inflammatory bowel disease is an uncommon cause. We describe a patient with recurrent OM and recurrent Crohn's disease.
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PMID:Imaging of orbital myositis in Crohn's disease. 1850 52

Idiopathic orbital inflammation, also known as orbital pseudotumor, describes a spectrum of idiopathic, non-neoplastic, non-infectious, space-occupying orbital lesions without identifiable local or systemic cause. The condition occurs mainly in young adults who may present with acute pain, proptosis, chemosis and limitations of extraocular movements. Decreased vision due to optic nerve infiltration and macular edema as a result of scleritis is less common sequel of orbital pseudotumor. Herein, we present a case of unilateral orbital pseudotumor in a young male who presented with chief complaints of painful decreased vision which was attributed to optic neuritis and macular edema as a result of scleritis. Imaging studies were helpful in the establishment of the correct diagnosis and patient's complaints improved with administration of systemic corticosteroids.
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PMID:Unilateral optic neuritis, scleritis and exudative retinal detachment due to recurrent orbital pseudotumor. 2396 Oct 32