Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0184567 (acute pain)
 3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The etiologic agent of seal finger (speck finger) is unknown. Seal finger occurs after a seal bite, and the symptoms include acute pain, swelling, discharge, and, in some cases, there is joint involvement. The discovery of Mycoplasma species in epidemics of seal disease prompted attempts to link seal finger to mycoplasma. Mycoplasma species were isolated in cultures of a specimen from the finger of an aquarium trainer who was bitten by a seal and of a specimen from the front teeth of the biting seal. The two Mycoplasma isolates were identical biochemically; they were serum-dependent and hydrolyzed arginine. The isolates were susceptible to tetracycline but resistant to erythromycin. By growth inhibition and immunofluorescent antibody tests, both strains were identified as Mycoplasma phocacerebrale, a mycoplasma isolated in an epidemic of seal disease occurring in the Baltic Sea. The patient's infection was treated successfully with tetracycline. To our knowledge, this is the first case in which a mycoplasma has been associated with seal finger.
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PMID:Isolation of Mycoplasma species from a patient with seal finger. 982 64

Seal finger is an infectious disease unknown to most physicians. It occurs after contact with seals, and the symptoms include acute pain, swelling, and, in some cases, there is joint involvement. The etiologic agent of Seal finger is now believed to be Mycoplasma, and treatment with high dose tetracycline has been successful for over 50 years. Seals are after years of protection once again hunted in Sweden, and the first case of Seal finger has already occurred.
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PMID:[Seal finger--a problem among hunters once again]. 1519 Jul 56