Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0184567 (acute pain)
 3,962 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 72-year-old female complained of acute pain on left eye movement followed by progressive exophthalmos. Neuroimaging revealed a large well-demarcated lesion consisting of solid and cystic parts, as well as bone destruction and hemorrhage, within the left orbital cavity. The preoperative diagnosis was pleomorphic adenoma with or without malignant transformation, or cavernous angioma. En bloc excision including adjacent tissues was planned to resolve the progressive symptoms and to obtain a histological diagnosis. The transcranial route was chosen since tumor invasion to the cranial base was possible. The histological diagnosis was pleomorphic adenoma. Pathological and preoperative radiological examinations indicated that repeated intratumoral hemorrhage had caused the orbital bone destruction and acute orbital pain. Neoplasms should be differentiated from a wide spectrum of other possible pathologies. Accurate clinical diagnosis of neoplasm in the orbital cavity is important for correct therapeutic management. Malignancy is generally suspected if painful and progressive signs and symptoms are associated with an orbital mass lesion. The present case suggests that pleomorphic adenoma should also be considered in the differential diagnosis. The therapeutic strategy for lacrimal gland tumors remains controversial, so a flexible management approach is required.
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PMID:Unusual progression of pleomorphic adenoma of the lacrimal gland: case report. 1612 59

Venous hemangioma is a rare, benign cardiac tumor, usually in young or adult males. A 61-year-old woman with a clinical history of radiofrequency catheter ablation had venous hemangioma of the right atrium diagnosed after an episode of acute pain in the precordial region. The incidental discovery of the mass, clinical evaluation, operative procedure, pathologic findings and follow-up are reported, as well as the epidemiology, natural history, and diagnostic and therapeutic approaches. Etiology may be related to damage to endothelial cells of the interatrial septum or to endocardial cells.
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PMID:Venous hemangioma in the right atrium possibly related to radiofrequency catheter ablation. 1872 39