Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0178874 (tumor progression)
40,807 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Mol 3394 Sep 2359 p53 2141 E-cadherin 1090 cytokine 1025 vascular endothelial growth factor 929 AKT 804 cage 771 catenin 752 PI3K 689 epidermal growth factor receptor 641 collagen 627 ERK 595 tyrosine kinase 537 mTOR 531 matrix metalloproteinase 526 VEGF 525 MAPK 501 CD8 500 histone 474 CD44 467 estrogen receptor 447 p21 434 vimentin 432 IL-6 431 EGFR 428 cyclin D1 425 chemokine 422 STAT3 413 TNM 404 MMP-9 364 ERK1 358 Bcl-2 358 CD4 354 HER2 350 Ki-67 342 fibronectin 342 MMP-2 328 osteosarcoma 306 PTEN 304 glycoprotein 300 caspase-3 295 IFN 295 IL-8 289 TNF 285 p38 279 N-cadherin 278 ras 269 lymphoid 267 c-Myc 267 beta-catenin 266 receptor tyrosine kinase 266 ATP 265 Rho 262 epidermal growth factor 262 androgen receptor 254 tumor necrosis factor 253 insulin 250 UTR 247 ubiquitin 244 EMT 243 BRAF 242 nodal 238 MEK 232 hepatocyte growth factor 230 EGF 230 p16 230 IL-10 229 TGF-beta 226 interferon 224 MRI 221 urokinase-type plasminogen activator 220 CXCR4 216 endoplasmic reticulum 215 proteasome 209 colon carcinoma 204 c-myc 201 KRAS 200 MMP9 199 proto-oncogene 197 more...

Disease tumor progression 40807 cancer 24351 tumor 24176 tumor growth 4431 breast cancer 4330 tumorigenesis 4162 metastases 3138 carcinoma 3023 carcinogenesis 2891 prostate cancer 1876 melanoma 1817 adenocarcinoma 1778 colorectal cancer 1720 hepatocellular carcinoma 1609 lung cancer 1524 squamous cell carcinoma 1233 primary tumor 935 gastric cancer 925 glioma 912 colon cancer 908 ovarian cancer 841 pancreatic cancer 772 aggressiveness 752 non-small cell lung cancer 729 tumor angiogenesis 709 glioblastoma 660 MCF 541 bladder cancer 537 renal cell carcinoma 525 tumor initiation 491 lung carcinoma 458 lymphoma 438 leukemia 407 dysplasia 390 cervical cancer 379 epithelial ovarian cancer 358 liver cancer 353 glioblastoma multiforme 343 osteosarcoma 337 brain tumor 324 adenoma 303 neuroblastoma 301 multiple myeloma 295 mammary tumor 283 obesity 273 liver cancer 266 solid tumor 265 sarcoma 261 neoplastic transformation 247 EMT 243 Hepatocellular carcinoma 239 metastatic melanoma 222 metastatic breast cancer 218 esophageal cancer 210 Barrett's esophagus 201 retinoblastoma 200 thyroid cancer 197 endometrial cancer 195 diabetes 194 esophageal cancer 194 lung metastases 178 liver metastases 178 Melanoma 177 skin cancer 175 aggression 174 tumor vasculature 172 SCID 172 B-cell lymphoma 159 oral cancer 155 astrocytoma 152 APC 147 acute myeloid leukemia 145 invasive cancer 143 fibrosarcoma 140 mole 140 bone metastases 136 cirrhosis 135 carcinoma in situ 135 ductal carcinoma in situ 135 ductal carcinoma 126 more...

Symptom pain 180 starvation 119 diarrhea 79 fatigue 73 nausea 66 cachexia 65 seizures 62 vomiting 59 exhaustion 54 anorexia 40 headache 38 collapse 34 abdominal pain 30 splenomegaly 29 weakness 29 acidity 28 anesthesia 27 nausea and vomiting 25 dyspnea 24 overweight 22 bone pain 21 cough 19 cancer pain 18 analgesia 15 ataxia 12 Ill 11 discomfort 10 back pain 9 discomfort 8 dizziness 7 chest pain 7 tinnitus 7 asthenia 7 hyperoxia 7 chills 6 hemoptysis 6 respiratory distress 6 constipation 6 shortness of breath 5 numbness 5 vertigo 5 Stiffness 5 myalgia 5 HSA 5 hypothermia 5 erythema 5 hepatomegaly 4 hepatosplenomegaly 4 Scratch 4 ENT 4 spasm 4 facial pain 4 exertional dyspnea 4 dysuria 4 low back pain 4 Fluctuation 4 lethargy 4 tremor 4 hemiplegia 3 skin damage 3 flushing 3 neck pain 3 agitation 3 paresis 3 paresthesia 3 sleepiness 3 leg edema 3 Postoperative pain 2 thinning 2 flank pain 2 hip pain 2 oliguria 2 fever of unknown origin 2 pallor 2 fasciculation 2 pelvic pain 2 syncope 2 intestinal bleeding 2 polyuria 2 dysarthria 2 more...

Drug lysine 206 Dermatol 187 ROS 150 IFN-gamma 112 CSF 112 IL-2 109 uPA 83 Bevacizumab 63 Monit 62 GEO 51 ROC 47 ETS 43 Sorafenib 39 MAP 39 Imatinib 38 Cardiovasc 36 Adriamycin 34 G-CSF 33 Docetaxel 28 Paraffin 28 NADH 27 ABC 27 Herceptin 27 CAM 25 Taxol 23 CPT-11 22 ascorbate 22 Gleevec 21 Gelatin 21 CTX 21 vitamin E 21 Activin 20 Gefitinib 20 Cetuximab 20 Mutagen 19 lactose 19 ICI 18 PTC 18 EE2 17 NVP 16 ADM 15 p75 15 Erlotinib 15 IL-11 14 Retinoic acid 14 CoCl2 14 Heme 14 Gel 14 CoCl2 14 Estrogens 13 TAT 13 Nitric Oxide 13 CCL 12 Everolimus 12 NBT 12 DNase I 11 Oxaliplatin 11 CTC 11 CTC 11 Growth hormone 11 ADR 11 Urokinase 11 Angiotensin II 10 Bortezomib 10 R1881 10 Portal 10 MRC 10 Etoposide 10 BLM 10 Hyaluronidase 9 ENT 9 Asn 9 Lovastatin 9 Indomethacin 9 VCR 9 Growth hormone 9 Glutathione 9 Parkin 8 caffeine 8 nitroglycerin 8 more...

Enzyme ERK 2047 mitogen-activated protein kinase 1355 focal adhesion kinase 849 luciferase 637 protein kinase 507 MEK 305 urokinase-type plasminogen activator 253 proteasome 214 caspase-3 209 protein kinase C 192 APC 156 PARP 154 reverse transcriptase 149 phosphatidylinositol 3-kinase 148 MMP 134 collagenase 123 AMP-activated protein kinase 122 prostate-specific antigen 106 phosphoinositide 3-kinase 104 ATPase 99 thrombin 97 MMP-3 94 matrix metalloproteinase 2 88 cdc2 85 GSK 85 ACS 85 cathepsin B 83 AMPK 81 plasmin 78 catalase 74 trypsin 74 AMPK 74 calcineurin 69 RNA polymerase 67 peroxidase 67 DNA methyltransferase 66 IKK 64 glutathione S-transferase 61 P-glycoprotein 61 matrix metalloproteinase 9 60 lactate dehydrogenase 57 caspase-8 55 demethylase 55 granzyme B 54 superoxide dismutase 53 arginase 51 lysyl oxidase 49 CD10 48 matriptase 45 caspase-9 44 cathepsin D 44 RNase 43 NADPH oxidase 43 alkaline phosphatase 42 NADPH oxidase 42 RNase 40 furin 38 complex I 38 PDK1 37 aldehyde dehydrogenase 36 aldehyde dehydrogenase 36 matriptase 35 topoisomerase 34 aldehyde dehydrogenase 34 aldehyde dehydrogenase 34 aldehyde dehydrogenase 34 MAP 32 phospholipase C 32 transcriptase 32 glyceraldehyde-3-phosphate dehydrogenase 32 cathepsin L 32 hyaluronidase 31 prolyl hydroxylase 30 topoisomerase 30 ALDH 30 tyrosinase 29 hyaluronidase 29 DNA polymerase 29 neuraminidase 29 NO synthase 29 more...

Compound DNA 3684 Dec 2605 Clin 1635 oxygen 1096 MDA 722 tyrosine 669 glucose 497 TNM 404 calcium 363 serine 358 methionine 317 MTT 309 TNF 285 ATP 266 lysine 259 cysteine 243 MEK 228 phosphate 227 sulfate 223 threonine 209 nitric oxide 191 arginine 190 acetate 184 zinc 177 water 169 iron 149 sodium 146 ASA 140 hydrogen 138 Vimentin 125 glutamine 120 leucine 106 galactose 105 retinoic acid 104 PEG 95 GlcNAc 86 ACS 84 ACS 84 Pac 82 5-FU 81 nitrogen 79 vitamin D 79 PGE 78 DDP 78 GTP 76 cAMP 75 AMP 72 alanine 71 SCC 70 anthracene 70 GSH 68 GSH 68 iodine 67 tryptophan 67 hyaluronic acid 67 bromide 67 proline 64 THP 62 ethanol 62 THP 61 PEG 60 glutamate 60 urea 59 DBA 58 Curcumin 58 Estrogen 58 PGE2 57 Estrogen 57 Insulin 56 PMA 56 Asp 55 copper 54 Thyroid 53 potassium 51 BCNU 51 NAD 50 His 50 tryptophan 49 Adriamycin 48 tryptophan 48 more...

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