Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0178874 (tumor progression)
40,807 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 3394
Sep 2359
p53 2141
E-cadherin 1090
cytokine 1025
vascular endothelial growth factor 929
AKT 804
cage 771
catenin 752
PI3K 689
epidermal growth factor receptor 641
collagen 627
ERK 595
tyrosine kinase 537
mTOR 531
matrix metalloproteinase 526
VEGF 525
MAPK 501
CD8 500
histone 474
CD44 467
estrogen receptor 447
p21 434
vimentin 432
IL-6 431
EGFR 428
cyclin D1 425
chemokine 422
STAT3 413
TNM 404
MMP-9 364
ERK1 358
Bcl-2 358
CD4 354
HER2 350
Ki-67 342
fibronectin 342
MMP-2 328
osteosarcoma 306
PTEN 304
more...
Disease
tumor progression 40807
cancer 24351
tumor 24176
tumor growth 4431
breast cancer 4330
tumorigenesis 4162
metastases 3138
carcinoma 3023
carcinogenesis 2891
prostate cancer 1876
melanoma 1817
adenocarcinoma 1778
colorectal cancer 1720
hepatocellular carcinoma 1609
lung cancer 1524
squamous cell carcinoma 1233
primary tumor 935
gastric cancer 925
glioma 912
colon cancer 908
ovarian cancer 841
pancreatic cancer 772
aggressiveness 752
non-small cell lung cancer 729
tumor angiogenesis 709
glioblastoma 660
MCF 541
bladder cancer 537
renal cell carcinoma 525
tumor initiation 491
lung carcinoma 458
lymphoma 438
leukemia 407
dysplasia 390
cervical cancer 379
epithelial ovarian cancer 358
liver cancer 353
glioblastoma multiforme 343
osteosarcoma 337
brain tumor 324
more...
Symptom
pain 180
starvation 119
diarrhea 79
fatigue 73
nausea 66
cachexia 65
seizures 62
vomiting 59
exhaustion 54
anorexia 40
headache 38
collapse 34
abdominal pain 30
weakness 29
splenomegaly 29
acidity 28
anesthesia 27
nausea and vomiting 25
dyspnea 24
overweight 22
bone pain 21
cough 19
cancer pain 18
analgesia 15
ataxia 12
Ill 11
discomfort 10
back pain 9
discomfort 8
chest pain 7
asthenia 7
hyperoxia 7
dizziness 7
tinnitus 7
constipation 6
respiratory distress 6
chills 6
hemoptysis 6
shortness of breath 5
Stiffness 5
more...
Drug
lysine 206
Dermatol 187
ROS 150
CSF 112
IFN-gamma 112
IL-2 109
uPA 83
Bevacizumab 63
Monit 62
GEO 51
ROC 47
ETS 43
MAP 39
Sorafenib 39
Imatinib 38
Cardiovasc 36
Adriamycin 34
G-CSF 33
Docetaxel 28
Paraffin 28
ABC 27
NADH 27
Herceptin 27
CAM 25
Taxol 23
CPT-11 22
ascorbate 22
CTX 21
Gleevec 21
Gelatin 21
vitamin E 21
Activin 20
Cetuximab 20
Gefitinib 20
lactose 19
Mutagen 19
PTC 18
ICI 18
EE2 17
NVP 16
more...
Enzyme
ERK 2047
mitogen-activated protein kinase 1355
focal adhesion kinase 849
luciferase 637
protein kinase 507
MEK 305
urokinase-type plasminogen activator 253
proteasome 214
caspase-3 209
protein kinase C 192
APC 156
PARP 154
reverse transcriptase 149
phosphatidylinositol 3-kinase 148
MMP 134
collagenase 123
AMP-activated protein kinase 122
prostate-specific antigen 106
phosphoinositide 3-kinase 104
ATPase 99
thrombin 97
MMP-3 94
matrix metalloproteinase 2 88
GSK 85
ACS 85
cdc2 85
cathepsin B 83
AMPK 81
plasmin 78
AMPK 74
trypsin 74
catalase 74
calcineurin 69
peroxidase 67
RNA polymerase 67
DNA methyltransferase 66
IKK 64
P-glycoprotein 61
glutathione S-transferase 61
matrix metalloproteinase 9 60
more...
Compound
DNA 3684
Dec 2605
Clin 1635
oxygen 1096
MDA 722
tyrosine 669
glucose 497
TNM 404
calcium 363
serine 358
methionine 317
MTT 309
TNF 285
ATP 266
lysine 259
cysteine 243
MEK 228
phosphate 227
sulfate 223
threonine 209
nitric oxide 191
arginine 190
acetate 184
zinc 177
water 169
iron 149
sodium 146
ASA 140
hydrogen 138
Vimentin 125
glutamine 120
leucine 106
galactose 105
retinoic acid 104
PEG 95
GlcNAc 86
ACS 84
ACS 84
Pac 82
5-FU 81
more...