Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0178874 (
tumor progression
)
40,807
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
3394
Sep
2359
p53
2141
E-cadherin
1090
cytokine
1025
vascular endothelial growth factor
929
AKT
804
cage
771
catenin
752
PI3K
689
epidermal growth factor receptor
641
collagen
627
ERK
595
tyrosine kinase
537
mTOR
531
matrix metalloproteinase
526
VEGF
525
MAPK
501
CD8
500
histone
474
CD44
467
estrogen receptor
447
p21
434
vimentin
432
IL-6
431
EGFR
428
cyclin D1
425
chemokine
422
STAT3
413
TNM
404
MMP-9
364
ERK1
358
Bcl-2
358
CD4
354
HER2
350
Ki-67
342
fibronectin
342
MMP-2
328
osteosarcoma
306
PTEN
304
more...
Disease
tumor progression
40807
cancer
24351
tumor
24176
tumor growth
4431
breast cancer
4330
tumorigenesis
4162
metastases
3138
carcinoma
3023
carcinogenesis
2891
prostate cancer
1876
melanoma
1817
adenocarcinoma
1778
colorectal cancer
1720
hepatocellular carcinoma
1609
lung cancer
1524
squamous cell carcinoma
1233
primary tumor
935
gastric cancer
925
glioma
912
colon cancer
908
ovarian cancer
841
pancreatic cancer
772
aggressiveness
752
non-small cell lung cancer
729
tumor angiogenesis
709
glioblastoma
660
MCF
541
bladder cancer
537
renal cell carcinoma
525
tumor initiation
491
lung carcinoma
458
lymphoma
438
leukemia
407
dysplasia
390
cervical cancer
379
epithelial ovarian cancer
358
liver cancer
353
glioblastoma multiforme
343
osteosarcoma
337
brain tumor
324
more...
Symptom
pain
180
starvation
119
diarrhea
79
fatigue
73
nausea
66
cachexia
65
seizures
62
vomiting
59
exhaustion
54
anorexia
40
headache
38
collapse
34
abdominal pain
30
weakness
29
splenomegaly
29
acidity
28
anesthesia
27
nausea and vomiting
25
dyspnea
24
overweight
22
bone pain
21
cough
19
cancer pain
18
analgesia
15
ataxia
12
Ill
11
discomfort
10
back pain
9
discomfort
8
chest pain
7
asthenia
7
hyperoxia
7
dizziness
7
tinnitus
7
constipation
6
respiratory distress
6
chills
6
hemoptysis
6
shortness of breath
5
Stiffness
5
more...
Drug
lysine
206
Dermatol
187
ROS
150
CSF
112
IFN-gamma
112
IL-2
109
uPA
83
Bevacizumab
63
Monit
62
GEO
51
ROC
47
ETS
43
MAP
39
Sorafenib
39
Imatinib
38
Cardiovasc
36
Adriamycin
34
G-CSF
33
Docetaxel
28
Paraffin
28
ABC
27
NADH
27
Herceptin
27
CAM
25
Taxol
23
CPT-11
22
ascorbate
22
CTX
21
Gleevec
21
Gelatin
21
vitamin E
21
Activin
20
Cetuximab
20
Gefitinib
20
lactose
19
Mutagen
19
PTC
18
ICI
18
EE2
17
NVP
16
more...
Enzyme
ERK
2047
mitogen-activated protein kinase
1355
focal adhesion kinase
849
luciferase
637
protein kinase
507
MEK
305
urokinase-type plasminogen activator
253
proteasome
214
caspase-3
209
protein kinase C
192
APC
156
PARP
154
reverse transcriptase
149
phosphatidylinositol 3-kinase
148
MMP
134
collagenase
123
AMP-activated protein kinase
122
prostate-specific antigen
106
phosphoinositide 3-kinase
104
ATPase
99
thrombin
97
MMP-3
94
matrix metalloproteinase 2
88
GSK
85
ACS
85
cdc2
85
cathepsin B
83
AMPK
81
plasmin
78
AMPK
74
trypsin
74
catalase
74
calcineurin
69
peroxidase
67
RNA polymerase
67
DNA methyltransferase
66
IKK
64
P-glycoprotein
61
glutathione S-transferase
61
matrix metalloproteinase 9
60
more...
Compound
DNA
3684
Dec
2605
Clin
1635
oxygen
1096
MDA
722
tyrosine
669
glucose
497
TNM
404
calcium
363
serine
358
methionine
317
MTT
309
TNF
285
ATP
266
lysine
259
cysteine
243
MEK
228
phosphate
227
sulfate
223
threonine
209
nitric oxide
191
arginine
190
acetate
184
zinc
177
water
169
iron
149
sodium
146
ASA
140
hydrogen
138
Vimentin
125
glutamine
120
leucine
106
galactose
105
retinoic acid
104
PEG
95
GlcNAc
86
ACS
84
ACS
84
Pac
82
5-FU
81
more...