Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0178874 (tumor progression)
 40,807 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Malignant transformation of endometriosis accounts for less than 1% of the cases. Most often it occurs in ovaries--75%. Extragenital tumor progression of endometriosis in pelvis and bowel constitutes 21.3%, the recto-sygmoid part of the colon occupying the majority of the cases. A case with rare combination of endometriosis, fibroma-thecoma and recto-sygmoid colonic cancer is presented. The presence of synchronous ovarian endometriosis and colonic cancer suggests the latter has developed on the grounds of endometriosis. More interesting is the association of the second tumor-ovarian fibroma-thecoma with the above mentioned hypothesis. To search for supporting arguments, we performed additional morphological, histochemical and immunohistochemical methods to define the origin of the intestinal neoplasm and the ovarian tumor. Regretfully the morphological analysis supports an accidental coincidence.
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PMID:[Ovarian endometriosis, fibroma-thecoma and colonic cancer--accidental combination or regularity?]. 2019