Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0162871 (abdominal aortic aneurysm)
8,664 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Aneurysm sac expansion following endovascular abdominal aortic aneurysm repair (EVAR) is typically associated with endoleaks that can be readily diagnosed on computed tomographic angiography (CTA), ultrasound, or catheter-directed arteriography. Sac hygromas are a cause of sac expansion without apparent endoleak and are presumed to be a result of ultrafiltration of serum manifested by accumulation of fibrinous, gelatinous material within the aneurysm sac following EVAR. Although there are no reported associated ruptures, sac expansion is nevertheless disconcerting and intervention is presumably indicated. We report a case of an expanding aneurysm after EVAR secondary to sac hygroma that was successfully treated with relining of the existing, original endograft.
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PMID:Sac hygroma after endovascular abdominal aortic aneurysm repair: successful treatment with endograft relining. 1750 29

We report two patients with perigraft hygromas after open abdominal aortic aneurysm replacement treated with relining the existing graft by covered stents with subsequent decrease in the size of the hygroma and disappearance of symptoms on follow-up. To our knowledge, these two patients are the first reported cases of successfully treated perigraft hygromas after open repair of abdominal aortic aneurysm using endograft relining of the existing grafts. This endovascular treatment avoids the need for aortic graft excision and replacement, which may be a challenging undertaking.
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PMID:Successful endovascular treatment of aneurysm sac hygroma after open abdominal aortic aneurysm replacement: a report of two cases. 1864 88

Perigraft hygroma is a known complication of prosthetic graft implantation. The specific etiology of perigraft hygromas is still unknown. We report 2 brothers who underwent open abdominal aortic aneurysm repairs with polytetrafluoroethylene grafts that developed progressively enlarging perigraft hygromas. This is the first case report of 2 brothers developing sac hygromas after open abdominal aortic aneurysm repair. This case demonstrates that there could be a genetic component associated with the development of perigraft hygromas and further investigation of genetic etiologies should be considered.
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PMID:Possible genetic component to the etiology of perigraft hygromas. 2309 Aug 41