Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0162871 (abdominal aortic aneurysm)
 8,664 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We present the case of a 62-year-old patient with a history of non-Hodgkin lymphoma (stage III) in complete remission after 6 cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone with rituximab (CHOP-R) in 2006. The patient was referred for a PET-CT scan because of suspicion of recurrence. On PET there were multiple lung lesions, a submandibular lesion (right side) and an impressive retroperitoneal mass with a hypermetabolic wall, and central necrosis invading all retroperitoneal structures (aorta). There was also an additional lesion in the anterior abdominal wall below the liver. It was concluded that it was recurrent non-Hodgkin lymphoma (stage IV). Contrast enhanced CT demonstrated a large, rupturing abdominal aortic aneurysm (AAA) with saccular ectasia of the posterior wall compatible with a mycotic aneurysm. The other sites of hypermetabolism corresponded to metastatic infectious lesions. Histopathology confirmed the mycotic infection. The patient underwent urgent surgery including bilateral axillofemoral stenting and removing a clot from the AAA twice. Intravenous antibiotics were started. This case clearly denotes the importance of contrast enhanced hybrid PET-CT systems in which the CT information is relevant for PET interpretation and not only for anatomic repair. With PET alone, the diagnosis would have been completely different.
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PMID:PET versus PET-CT in patient with suspicion of non-Hodgkin lymphoma recurrence. 1803 52

Mycotic aneurysm is a rare and life-threatening disorder. Computed tomography (CT) is considered to be the best diagnostic imaging modality that can detect an abdominal aortic aneurysm and changes in the surrounding structures. More recently, F-18 fluorodeoxyglucose (FDG) PET would seem to hold promise for the diagnosis of focal infection and during the follow-up after antibiotic treatment. We present a case of an infected abdominal aortic aneurysm due to Salmonella enteritidis. In this case, a combination of CT and FDG PET/CT provided accurate information for the diagnosis of the infected abdominal aortic aneurysm. Moreover, FDG PET/CT made an important contribution for monitoring response to antibiotic therapy.
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PMID:F-18 FDG PET/CT in the management of infected abdominal aortic aneurysm due to Salmonella. 1858 Feb 40

Mycotic aneurysm secondary to tuberculous infection of the aorta is a rare and life-threatening disease. We report a single-center experience of three patients treated with a combination of surgical aortic replacement and prolonged antituberculosis therapy. The first case is a 34-year-old woman with a suprarenal abdominal aortic aneurysm, the second case is a 77-year-old man with an infrarenal abdominal aortic aneurysm and a right psoas abscess, the third case is a 37-year-old woman with an infrarenal abdominal aortic aneurysm. All patients had a favorable outcome with a mean follow-up of 6.2 years (range, 6 months-10 years). Early diagnosis and a combination of surgical intervention (aortic reconstruction and extensive excision of the infected field) and prolonged antituberculous drug therapy provide long-term survival without evidence of recurrence after tuberculous aortic involvement.
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PMID:Tuberculous aneurysms of the abdominal aorta. 1899 19

Abdominal pain, a common condition, has been reported in up to 37|X% of-patients with systemic lupus erythematosus (SLE) (1). There are many possible causes including peritonitis, pancreatitis, mesenteric vasculitis, thrombosis of the mesenteric vessels, intra-abdominal infections, or side effects of the medications used in the treatment of the disease, especially non-steroidal anti-inflammatory drugs (1-3). However, ruptured mycotic aneurysm of the abdominal aorta has rarely been mentioned as a cause of abdominal pain in SLE (1-3). We recently saw a patient with SLE who had an acute surgical abdomen, which proved to have been caused by a rupture of a mycotic abdominal aortic aneurysm.
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PMID:Ruptured mycotic abdominal aortic aneurysm in a patient with systemic lupus erythematosus. 1907 42

An infected aortic aneurysm, or mycotic aneurysm, is a rare arterial dilatation due to destruction of the infected vessel wall. Common pathogens resulting in an infected aortic aneurysm are Salmonella and Clostridium species, as well as Staphylococcus aureus; Morganella morganii, on the other hand, is very rare. An infected abdominal aortic aneurysm has tendencies to grow rapidly and to rupture. The mortality rate is high in patients undergoing emergent surgical intervention. We report the case of a 65-year-old man who presented with an infected abdominal aortic aneurysm caused by M. morganii. A high index of suspicion and imaging tests are necessary in order to diagnose an infected aortic aneurysm.
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PMID:Infected abdominal aortic aneurysm due to Morganella morganii: CT findings. 2035 11

Mycotic aneurysm of the aorta is an uncommon condition, and Group B Streptococcus (GBS) is exceedingly rare in this setting. We present the first reported case of a GBS-infected abdominal aortic aneurysm (AAA) in North America. Key clinical and imaging findings and pathologic correlation are highlighted. A relevant review of the literature is discussed, which will bring the reader up to date with this specific disease entity.
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PMID:Group B streptococcus mycotic aneurysm of the abdominal aorta: report of a case and review of the literature. 2246 48

This study reports on a contained rupture of mycotic abdominal aortic aneurysm secondary to coagulase negative staph successfully repaired with aorto bi-iliac polytetrafluoroethylene (PTFE) Gor-Tex graft. An 8-year-old Saudi male patient was found to have infective endocarditis by coagulase negative staph with mitral valve (MV) leaflet damage, which was repaired with mechanical MV. Post-cardiac surgery, he complained of intermittent abdominal and back pain, until he became more symptomatic and had a sudden abdominal pain. Ultrasound showed abdominal aortic aneurysm (AAA), as well as the CT scan showed contained posterior rupture of AAA. He was operated immediately and the aorta was repaired with bifurcated PTFE Gor-Tex graft. He tolerated the operation, and he was given antibiotic coverage according to sensitivity. Tissue culture of the aorta confirmed coagulase negative staph. The strong relation between infective endocarditis and mycotic aneurysm should make a high index of suspicion of developing abdominal aortic aneurysm in children. Utilizing the PTFE graft with an omental patch is safe and life saving.
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PMID:Successful repair of a contained rupture of mycotic aortic aneurysm in an 8-year-old child using polytetrafluoroethylene graft. 2282 15

We report a case of a 71-year-old man with a mycotic aneurysm of the aortic arch who presented with progressive hoarseness. Three weeks prior to this event the patient was admitted to an outside hospital in septic condition and was diagnosed with a mycotic abdominal aortic aneurysm. Resection of the infected abdominal aortic aneurysm with right axillofemoral and femoral-femoral bypass grafts was performed and the patient was discharged home on intravenous antibiotics. At our institution, the aortic arch aneurysm was treated with extensive debridement and replaced with a Dacron prosthesis under circulatory arrest with antegrade cerebral perfusion through the axillofemoral bypass.
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PMID:Mycotic aneurysm of the aortic arch presenting with left vocal cord palsy. 2381 81

Miliary tuberculosis refers to the clinical disease resulting from the hematogenous dissemination of Mycobacterium tuberculosis. A tuberculous aneurysm of the aorta is exceedingly rare. Contiguous tuberculosis in the form of lymphadenitis is generally responsible for the aortic involvement. We report a case of tuberculous mycotic aneurysm in patient with miliary disease, not affected by a cellular immunodeficiency and with no other common risk factor for infection. He received anti-tubercular therapy and endovascular stenting before the identification of Mycobacterium tuberculosis in lung, lymph nodes, and gastric lavage. The clinician should be aware that a mycotic abdominal aortic aneurysm could be caused by M. tuberculosis, even if microbiological confirmation is lacking or is negative, especially if a contiguous focus of tubercular infection is detected.
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PMID:Disseminated tuberculosis in an immunocompetent patient. 2393 45

We report a case of cryptococcal aortitis in a 59-year-old man presenting as a symptomatic suprarenal abdominal aortic aneurysm (AAA). The patient underwent repair of his aneurysm using a rifampin-soaked graft with omental wrapping. Intraoperative Gram stains showed yeast organisms, the cultures eventually grew Cryptococcus neoformans with results available 43 days postoperatively. He was started on antifungal therapy intraoperatively and will be on lifelong antifungal treatment. Our case is the first report of cryptoccocal aortitis presenting as a symptomatic AAA; the diagnosis of a true mycotic aneurysm was made intraoperatively.
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PMID:Cryptococcal aortitis presenting as a symptomatic abdominal aortic aneurysm. 2545 84


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