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Query: UMLS:C0162871 (abdominal aortic aneurysm)
 8,664 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Autologous platelet labelling was used to calculate platelet half-life in 860 patients with symptoms of coronary heart disease and/or peripheral vascular disease. Abnormal platelet deposition indicating an abdominal aortic aneurysm was found in 21 by gamma-camera imaging after reinjection of autologous indium-111 labelled platelets. Aneurysms detected by imaging were confirmed by angiography, computer tomography, and at subsequent surgery.
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PMID:Detection of aneurysms by gamma-camera imaging after injection of autologous labelled platelets. 615 Mar 67

Seventy-three patients with atherosclerotic peripheral vascular disease underwent prospective evaluation of the abdominal aorta by both physical examination and ultrasonography. The objective was to find out the incidence of abdominal aortic aneurysms by these two methods. Early diagnosis may decrease the morbidity and mortality associated with the disease. Ultrasonography established an incidence of 9.6 percent, whereas physical examination only demonstrated a 2.6 percent incidence. We recommend that routine ultrasonographic examination be performed on patients with peripheral atherosclerotic vascular disease in order to demonstrate the presence or absence of abdominal aortic aneurysm.
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PMID:Incidence of abdominal aortic aneurysms in patients with atheromatous arterial disease. 663 62

Twenty-eight patients with abdominal aortic aneurysm were examined by computed tomography (CT) and aortography. They subsequently underwent aneurysmectomy and reconstruction of the aorta. CT provided in most of the cases the same or more accurate preoperative information than aortography. CT is comfortable for the patient, less invasive and faster than aortography and can be done as an outpatient procedure. Thus, we recommend CT to be the primary method for preoperative evaluation of abdominal aortic aneurysm. In selected cases aortography gives additional information regarding the relationship to the renal arteries (when the aorta is very tortuous), the occurrence of renal artery stenosis, and peripheral vascular disease.
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PMID:Computed tomography versus aortography for preoperative evaluation of abdominal aortic aneurysm. 673 Oct 24

The association of coronary artery disease and peripheral vascular disease was studied to determine the influence of coronary artery disease on early and late mortality rates after surgical reconstruction for peripheral occlusive vascular disease and abdominal aortic aneurysm. Between January 1976 and December 1978, 161 consecutive patients underwent surgery for peripheral occlusive vascular disease or abdominal aortic aneurysm. The patients were 35-86 years old (mean 63.3 years). Thirty patients (18.6%) had abdominal aortic aneurysmectomies, 59 (36.7%) had aortoiliac reconstruction with or without femoropopliteal bypass and 72 (44.7%) had procedures for femoropopliteal disease. The 30-day hospital mortality rate was 6.7% for abdominal aortic aneurysm (n = 2), 3.4% for aortoiliac reconstruction (n = 2) and 1.4% for femoropopliteal procedures (n = 1). Myocardial infarction was the cause of 40% (n = 2) of the early postoperative deaths. The early mortality rate of patients with a history of angina or myocardial infarction was 5.4% (two of 37), while the early mortality rate among patients without such a history was 2.4% (three of 124). The mortality rate from myocardial infarction during the late observation period was 65% (15 of 23). The freedom from myocardial infarction was 90% at 30 months and 75% at 60 months. The overall survival rate was 87% at 30 months and 71% at 60 months. The late mortality rate was assessed with respect to various risk factors: coronary artery disease (n = 31), previous vascular surgery (n = 19) and diabetes mellitus (n = 7). Among the 63 patients who had one or more of the risk factors, the late cardiac mortality rate was 20.6% (n = 13). The late cardiac mortality rate for for the 78 patients with no risk factors was 3.8% (n = 3). An additional 10 patients with previous coronary artery bypass (n = 9) or angiography (n = 1) experienced no early or late mortality. The freedom from late cardiac death at 60 months was 71% for the high-risk group (63% patients) and 96% for the low-risk group. The study shows that coronary artery disease is a major determinant of both early and late mortality after arterial reconstruction. The status of the myocardium should be assessed before peripheral vascular surgery, as selective myocardial revascularization may improve survival in these patients.
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PMID:Influence of ischemic heart disease on early and late mortality after surgery for peripheral occlusive vascular disease. 708 52

A questionnaire survey has been carried out to assess the circumstances under which general practitioners refer patients with peripheral vascular disease to a district general hospital. A single-page questionnaire was sent to 100 general practitioners seeking information about their referral of patients with claudication, ischaemic rest pain or abdominal aortic aneurysms. Of the 77% who responded, over half would not refer a 70-year-old with claudication at half a mile or an 80-year-old with claudication at 100 m, and 44% would not refer an 80-year-old with a palpable abdominal aortic aneurysm. The results suggest that many elderly patients with symptomatic claudication or asymptomatic aneurysms are not currently referred. Changing referral patterns due to a heightened awareness of minimally invasive methods of treatment or the benefits of aneurysm surgery have the potential for profound effects upon vascular surgical work-load.
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PMID:General practitioner referral of patients with symptoms of peripheral vascular disease. 752 61

To evaluate the prevalence of abdominal aortic aneurysm (AAA) and occlusive peripheral vascular disease (PVD) in Japanese residents, and to examine the correlations between these diseases and the risk factors of atherosclerosis, 348 residents of a village in central Japan aged between 60 and 79 years were screened. The screening for AAA was performed using ultrasonography (US) and that for PVD was performed by palpation and Doppler US. No AAA was found, and a right common iliac arterial aneurysm was detected in a 79-year-old man (0.3%). The mean diameter of the infrarenal abdominal aorta was 18.7 mm and an abdominal aorta of 25 mm or greater in diameter was seen in 16 participants (4.6%), all of whom need to be followed up. PVD was suspected in two patients (0.6%) with a low ankle brachial pressure index. Of a total of five patients diagnosed or suspected of having a common iliac arterial aneurysm or PVD, four (80%) had at least one risk factor for atherosclerosis. Thus, we conclude that Japanese residents with risk factors predisposing them to atherosclerosis such as hypertension, obesity, abnormal serum lipid levels, and a history of smoking should be selectively screened for AAA and PVD due to the low prevalence of these diseases and from the viewpoint of cost-effectiveness.
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PMID:Screening for abdominal aortic aneurysm and occlusive peripheral vascular disease in Japanese residents. 754 72

Renal artery stenoses (RASs) that are unsuspected on clinical grounds are common in patients with peripheral vascular disease. These lesions may be missed in patients with abdominal aortic aneurysms (AAAs) who undergo arteriography based on selective clinical indications alone. We reviewed 98 consecutive patients with AAAs to determine how often selective arteriography would fail to diagnose unsuspected RAS. The location and degree of RASs were noted on preoperative arteriograms, which were routinely obtained in all patients considered for AAA repair during the study period. Medical records were studied to determine the presence of selective clinical indications for preoperative arteriography (moderate to severe hypertension or renal insufficiency). Twenty-four patients had a significant (> or = 50% diameter loss) RAS, and 10 patients had a severe (> or = 75% diameter loss) RAS or renal artery occlusion. Patients with significant RAS had a higher incidence of hypertension (p = 0.035) and renal insufficiency (p = 0.018). All 10 patients with severe RASs required at least two antihypertensive medications to control their hypertension compared with 22 of 88 patients who did not have a severe RAS (p < 0.001). Forty-three patients had an indication for arteriography according to selection criteria (renal insufficiency, moderate or severe hypertension, or both). No severe RASs were found in patients who did not meet the selection criteria for arteriography. Using arteriography based on the presence of hypertension requiring two or more medications for control will detect the vast majority of severe, unsuspected RASs in AAA patients.
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PMID:Detection of unsuspected renal artery stenoses in patients with abdominal aortic aneurysms: refined indications for preoperative aortography. 831 84

Coronary artery ectasia (CAE) is the saccular or fusiform dilatation of a coronary artery. CAE is found in 1.2% to 4.9% of patients at autopsy or during angiographic studies, with a similar prevalence of CAE found in patients with atherosclerotic peripheral vascular disease (PVD). Abdominal aortic aneurysm (AAA) and CAE are similar in pathogenesis and histology. To determine whether CAE occurs more frequently in patients with AAA than in occlusive forms of atherosclerotic PVD, a review of coronary angiograms was performed in patients who underwent cardiac catheterization and vascular reconstruction for AAA or occlusive atherosclerotic PVD of the lower extremities. Of 72 patients with AAA, 15 had CAE (20.8%) compared with only 2 of 69 patients with atherosclerotic PVD (2.9%) (p < 0.003). CAE was predominantly discrete, located in the left coronary system, and associated with significant coronary atherosclerosis. CAE may be more prevalent in patients with AAA resulting from a similar pathogenetic process.
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PMID:Coronary arterial ectasia: increased prevalence in patients with abdominal aortic aneurysm as compared to occlusive atherosclerotic peripheral vascular disease. 841 47

Atherosclerosis and its complications are associated with high morbidity and mortality in the elderly. One of these complications is abdominal aortic aneurysm which may be prevented from rupturing if diagnosed early. Screening for aortic aneurysm was carried out in Jeddah, which is in the western region of Saudi Arabia, to identify the magnitude of this problem. Three groups were studied: patients with hypertension (n = 101), patients with peripheral vascular disease (n = 71) and a third group of a controls (n = 220). The mean (range) age of the whole sample was 66.0 (60-80) years. Evidence of aortic aneurysm was found in seven participants: five in the peripheral vascular disease group (7.0%), one in the hypertensive group (1.0%) and one in the controls (0.5%). In view of the expected increase in the elderly population of Saudi Arabia, as a result of improvements in health care which have recently been achieved, it is expected that a similar increase in the incidence of abdominal aortic aneurysm may occur. Routine screening for abdominal aortic aneurysm in the elderly, especially in those with peripheral vascular disease, may be worthwhile.
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PMID:Screening for abdominal aortic aneurysm in the Jeddah area, western Saudi Arabia. 863 54

Abdominal aortic aneurysmal disease may lead to serious or fatal complications. Recent publications have noted the presence of aneurysms in as many as 14% of male patients older than 60 years with a history of cigarette smoking and peripheral vascular disease. To identify the prevalence of abdominal aortic aneurysm in a similar group of patients, a prospective screening study of male patients more than 60 years of age who have severe peripheral or cerebrovascular disease was performed. This article presents the results of this study and examines the rationale for screening for abdominal aortic aneurysm.
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PMID:Screening a high-risk population for abdominal aortic aneurysm. 890 Jul 70


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