Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0162671 (MELAS)
 587 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MELAS 0.559
MERRF 0.098
NARP 0.016
LHON 0.010
MNGIE 0.006
IOSCA 0.004
SANDO 0.004
VARS2 protein 0.002
POLG protein 0.002
CADASIL 0.001
tRNA 0.001
DARS2 0.001
MT-TK 0.001
EFG2 0.001
ORNT2 0.001
TL1A 0.001
CARS2 0.001
MT-ND3 0.001
VARS2 0.001
MTND5 0.001
FOXRED1 0.001
POLG 0.000
HIBCH 0.000
FPRL2 0.000
ND5 0.000
PDHC 0.000
GTPBP3 0.000
Tim14 0.000
RARS2 0.000
NDUFAF2 0.000
cytochrome c oxidase 0.000
Caytaxin 0.000
CMT4A 0.000
PCWH 0.000
ornithine transporter 0.000
FBXL4 0.000
dGK 0.000
NADH dehydrogenase subunit 3 0.000
MT-CO2 0.000
TMEM70 0.000
MTO1 0.000
RXRB 0.000
MT-ND5 0.000
Humanin 0.000
TRMU 0.000
HADHB 0.000
NADH-ubiquinone reductase 0.000
ASNS 0.000
ALDH5A1 0.000
AHS 0.000
ND1 0.000
ND6 0.000
CMT2A 0.000
pyruvate dehydrogenase complex 0.000
MT-ND6 0.000
CHCHD2 0.000
Transcription factor E3 0.000
Thrombin receptor 0.000
DNA polymerase gamma 0.000
COL4A1 0.000
OXPHOS 0.000
NDUFV1 0.000
mitochondrial transcription termination factor 0.000
MT-ND4 0.000
Succinic dehydrogenase 0.000
FPRL1 0.000
COXIII 0.000
ATPase subunit 6 0.000
ATF5 0.000
ATPase6 0.000
ATPase 6 0.000
PRCC 0.000
ND4 0.000
SDH 0.000
PDHA1 0.000
HHH 0.000
TPK1 0.000
RRF 0.000
WFS1 0.000
ASK 0.000
thymidine kinase 2 0.000
E1 alpha 0.000
frataxin 0.000
HEMO 0.000
GDAP1 0.000
EA1 0.000
COL4A2 0.000
G4.5 0.000
leucyl-tRNA synthetase 0.000
NADH-ubiquinone oxidoreductase 0.000
FRDA 0.000
TK2 0.000
SACS 0.000
argininosuccinate synthase 0.000
Barth syndrome 0.000
NADH dehydrogenase subunit 1 0.000
complex I) 0.000
eIF-2B 0.000
SLC20A2 0.000
MRI 0.000
Pyruvate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
PMD 0.000
ND3 0.000
ND4L 0.000
CMT2 0.000
2-oxoglutarate dehydrogenase 0.000
IGFBP3 0.000
CPT II 0.000
neurofibromatosis type 2 0.000
mtTFA 0.000
cathepsin A 0.000
P43 0.000
NIDDM 0.000
COII 0.000
GAN 0.000
HLA-B51 0.000
MFN2 0.000
PEO 0.000
TCI 0.000
mitofusin 2 0.000
Alport syndrome 0.000
GDF15 0.000
PDC 0.000
COX 0.000
ATP6 0.000
medium-chain acyl-CoA dehydrogenase 0.000
Islet-1 0.000
SCA1 0.000
Cytochrome b 0.000
biotinidase 0.000
AED 0.000
MLD 0.000
NCL 0.000
fumarate hydratase 0.000
plectin 0.000
thymidine phosphorylase 0.000
N-acetylaspartate 0.000
TFE3 0.000
carnitine palmitoyltransferase 0.000
cytochrome 0.000
ASL 0.000
fragile X mental retardation protein 0.000
COX1 0.000
PGD 0.000
alpha-ketoglutarate dehydrogenase 0.000
mitochondrial transcription factor A 0.000
She 0.000
X-linked adrenoleukodystrophy 0.000
elongation factor G 0.000
IP1 0.000
ALD 0.000
ATP 0.000
NADH 0.000
Golgi protein 0.000
aniridia 0.000
fumarase 0.000
cytochrome aa3 0.000
APH 0.000
MRS 0.000
ND2 0.000
TCS 0.000
PND 0.000
HAS 0.000
Fibroblast growth factor 21 0.000
AAG 0.000
NADH dehydrogenase 0.000
CSF 0.000
glucose transporter 4 0.000
lipoamide dehydrogenase 0.000
Q10 0.000
EF-Tu 0.000
IDDM 0.000
Axin 0.000
glutathione peroxidase 1 0.000
EPI 0.000
E2 protein 0.000
HSP60 0.000
citrate synthase 0.000
Apaf-1 0.000
Cx32 0.000
Mol 0.000
intrinsic factor 0.000
enigma 0.000
MRP 0.000
MnSOD 0.000
platelet-derived 0.000
ATP synthase 0.000
COX2 0.000
ubiquinone 0.000
P100 0.000
GAD65 0.000
X-linked 0.000
ATF4 0.000
ADC 0.000
pyruvate carboxylase 0.000
urocortin 0.000
Polymerase 0.000
Growth hormone 0.000
phosphoglycerate kinase 0.000
COI 0.000
osteosarcoma 0.000
aconitase 0.000
thyroid peroxidase 0.000
BTR 0.000
SIN 0.000
Hsp60 0.000
SWI 0.000
connexin 43 0.000
retinol-binding protein 0.000
Cytochrome c 0.000
MLC 0.000
HIF-1alpha 0.000
X-linked recessive 0.000
glutamate decarboxylase 0.000
HSP 0.000
DAF 0.000
XIAP 0.000
axonal 0.000
AGS 0.000
MDS 0.000
DR3 0.000
DDP 0.000
insulin 0.000
creatine kinase 0.000
ENT 0.000
Dicer 0.000
inhibitor of apoptosis 0.000
GRP78 0.000
acetyl-CoA carboxylase 0.000
p13 0.000
B19 0.000
ERG 0.000
sarcomeric 0.000
AAA 0.000
HCC 0.000
IMP 0.000
NAC 0.000
brain) 0.000
Rett syndrome 0.000
DR4 0.000
GHRH 0.000
CPT 0.000
flavoprotein 0.000
NAD 0.000
MRC 0.000
cystatin C 0.000
oxidoreductase 0.000
ECD 0.000
SCF 0.000
ADHD 0.000
PGC 0.000
Sep 0.000
glutamic acid decarboxylase 0.000
strabismus 0.000
ceruloplasmin 0.000
cardiac muscle 0.000
endonuclease 0.000
nitric oxide synthase 0.000
P-selectin 0.000
endothelial nitric oxide synthase 0.000
CHOP 0.000
asymmetrical 0.000
STAT3 0.000
acetylcholine receptor 0.000
CTX 0.000
phosphoinositide 3-kinase 0.000
cytochrome c 0.000
ADP 0.000
cytochrome b 0.000
LDL receptor 0.000
NAD+ 0.000
transcriptional activator 0.000
glucagon 0.000
vascular cell adhesion molecule-1 0.000
glucose transporter 0.000
desmin 0.000
AMP-activated protein kinase 0.000
HEK 0.000
antioxidant enzyme 0.000
calcineurin 0.000
ROS 0.000
RhoA 0.000
ABC 0.000
unknown function 0.000
peroxisome proliferator-activated receptor 0.000
heat shock protein 0.000
insulin receptor 0.000
RNase 0.000
adiponectin 0.000
vascular endothelium 0.000
FDG 0.000
caspase-3 0.000
polypeptide 0.000
mTOR 0.000
chronic renal failure 0.000
GTPase 0.000
prothrombin 0.000
Met 0.000
amyloid precursor protein 0.000
transferrin 0.000
reserved 0.000
ACTH 0.000
SOD 0.000
kit 0.000
catalase 0.000
glutathione peroxidase 0.000
superoxide dismutase 0.000
nodal 0.000
threonine 0.000
reductase 0.000
ATPase 0.000
growth hormone 0.000
fibrinogen 0.000
Bcl-2 0.000
thrombin 0.000
Pol 0.000
olfactory 0.000
GSH 0.000
HLA 0.000
more...
Disease
MELAS 0.997
MELAS 0.758
MERRF 0.096
mitochondrial encephalomyopathy 0.041
lactic acidosis 0.036
mitochondrial myopathy 0.032
Chronic progressive external ophthalmoplegia 0.010
mitochondrial disease 0.007
Kearns-Sayre syndrome 0.007
MNGIE 0.006
IOSCA 0.005
Leigh syndrome 0.005
SCAE 0.005
encephalopathy 0.004
SANDO 0.004
Leber's hereditary optic neuropathy 0.004
MILS 0.001
Central deafness 0.001
CADASIL 0.001
DCMA 0.001
stroke 0.001
CARASIL 0.001
Alpers 0.001
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy 0.001
myoclonus epilepsy 0.001
Auditory agnosia 0.001
myopathy 0.000
skin pigmentation disorder 0.000
deafness 0.000
PCWH 0.000
CMT2K 0.000
Membranous lipodystrophy 0.000
PDH deficiency 0.000
Russian spring-summer encephalitis 0.000
CMT4A 0.000
Complex I deficiency 0.000
Demyelinating Polyneuropathy 0.000
Alternating hemiplegia of childhood 0.000
FXTAS 0.000
Pearson's syndrome 0.000
hemiparesis 0.000
Giant axonal neuropathy 0.000
Wolfram syndrome 0.000
Oculodentodigital dysplasia 0.000
infectious encephalitis 0.000
migraine 0.000
epilepsy 0.000
sensorineural hearing loss 0.000
Pelizaeus-Merzbacher 0.000
FRDA 0.000
NSHL 0.000
hemiplegic migraine 0.000
marantic endocarditis 0.000
Friedreich's ataxia 0.000
cardiomyopathy 0.000
Kufs' disease 0.000
Barth syndrome 0.000
Jervell and Lange-Nielsen syndrome 0.000
leukoencephalopathy 0.000
status epilepticus 0.000
diabetes 0.000
optic atrophy 0.000
lipoproteinemia 0.000
Familial hemiplegic migraine 0.000
MCAD deficiency 0.000
hyperornithinemia 0.000
glutaric aciduria 0.000
Alexander disease 0.000
CMTX 0.000
GAN 0.000
hearing disability 0.000
retinitis pigmentosa 0.000
Reye 0.000
aphasia 0.000
Fahr's disease 0.000
Refsum disease 0.000
global aphasia 0.000
Inborn errors of metabolism 0.000
idiopathic cardiomyopathy 0.000
PMD 0.000
Herpes simplex encephalitis 0.000
Deafness 0.000
schizophrenic psychosis 0.000
brain atrophy 0.000
hypertrichosis 0.000
dementia 0.000
vascular headache 0.000
neuropathy 0.000
dysfibrinogenemia 0.000
primary disorders 0.000
Pelizaeus-Merzbacher disease 0.000
Waardenburg syndrome 0.000
bilateral cataracts 0.000
xanthomatosis 0.000
arteriopathy 0.000
ornithine transcarbamylase deficiency 0.000
vascular disease 0.000
Canavan 0.000
CLE 0.000
common migraine 0.000
dysphasia 0.000
enzyme deficiency 0.000
PDC 0.000
cerebral infarction 0.000
hypertrophic cardiomyopathy 0.000
malignant hyperthermia 0.000
SCA1 0.000
Binswanger 0.000
hearing disorder 0.000
developmental delay 0.000
hereditary neuropathy 0.000
anal atresia 0.000
agnosia 0.000
gastrointestinal dysfunction 0.000
apraxia 0.000
mild mental retardation 0.000
encephalomalacia 0.000
Menkes 0.000
neuronal ceroid lipofuscinosis 0.000
mutism 0.000
neonatal asphyxia 0.000
incontinentia pigmenti 0.000
cerebellar syndrome 0.000
ALD 0.000
Krabbe disease 0.000
fits 0.000
Alport syndrome 0.000
neurological disease 0.000
prolapse 0.000
Optic nerve 0.000
McArdle's disease 0.000
motor aphasia 0.000
paralytic ileus 0.000
retinopathy 0.000
Focal segmental glomerulosclerosis 0.000
Wilson's disease 0.000
AEM 0.000
moderate mental retardation 0.000
POEMS syndrome 0.000
diabetic ketoacidosis 0.000
Gerstmann 0.000
NPS 0.000
focal epilepsy 0.000
congenital disorder 0.000
microcytic anemia 0.000
MRS 0.000
borreliosis 0.000
Wernicke's encephalopathy 0.000
dysplastic nevi 0.000
CLN3 0.000
AMN 0.000
scotoma 0.000
Harada 0.000
Horton 0.000
glomerulosclerosis 0.000
PND 0.000
generalized seizure 0.000
attention deficit disorder 0.000
congenital rubella 0.000
Reye's syndrome 0.000
Wolff-Parkinson-White syndrome 0.000
growth hormone deficiency 0.000
vitamin E deficiency 0.000
leukodystrophy 0.000
homocystinuria 0.000
LMS 0.000
EPI 0.000
CAA 0.000
delayed puberty 0.000
protein deficiency 0.000
congenital infection 0.000
hypopituitarism 0.000
Hashimoto's thyroiditis 0.000
PDS 0.000
NF2 0.000
myasthenia 0.000
Cockayne syndrome 0.000
megacolon 0.000
cognitive impairment 0.000
primary central nervous system lymphoma 0.000
Addison's disease 0.000
muscular atrophy 0.000
metachromatic leukodystrophy 0.000
mental retardation 0.000
CAA 0.000
Addison's disease 0.000
glucose intolerance 0.000
paranoia 0.000
Charcot-Marie-Tooth disease 0.000
G6PD deficiency 0.000
blindness 0.000
seborrheic dermatitis 0.000
Fabry 0.000
gastrointestinal disease 0.000
Rett syndrome 0.000
gestational diabetes mellitus 0.000
retinitis 0.000
encephalitis 0.000
failure to thrive 0.000
DRS 0.000
vitiligo 0.000
type 2 diabetes 0.000
Tay-Sachs disease 0.000
Marfan syndrome 0.000
Fanconi syndrome 0.000
peripheral neuropathy 0.000
dystocia 0.000
mental retardation 0.000
sensory neuropathy 0.000
right bundle branch block 0.000
osteosarcoma 0.000
DM1 0.000
Ehlers-Danlos syndrome 0.000
ileus 0.000
LCA 0.000
brain edema 0.000
moyamoya 0.000
Autism spectrum disorder 0.000
MLC 0.000
systemic disease 0.000
ventricular dilatation 0.000
acute tubular necrosis 0.000
antiphospholipid syndrome 0.000
premature aging 0.000
AGS 0.000
diplopia 0.000
aspiration pneumonia 0.000
dilated cardiomyopathy 0.000
intermittent claudication 0.000
glomerulopathy 0.000
endometritis 0.000
MDS 0.000
coma 0.000
HSP 0.000
EMA 0.000
Parkinson's disease 0.000
complex partial seizures 0.000
CNS diseases 0.000
disorientation 0.000
hyperthyroidism 0.000
muscular dystrophy 0.000
telangiectasia 0.000
Syndrome 0.000
optic neuritis 0.000
hypoparathyroidism 0.000
degenerative disease 0.000
tetraplegia 0.000
HCC 0.000
AAA 0.000
acute renal failure 0.000
heart block 0.000
phenylketonuria 0.000
psychosis 0.000
hyperhomocysteinemia 0.000
nystagmus 0.000
hypogonadotropic hypogonadism 0.000
polyneuropathy 0.000
wasting 0.000
meninges 0.000
arteriovenous malformation 0.000
preeclampsia 0.000
Alzheimer's disease 0.000
hyperuricemia 0.000
herpes 0.000
varicella 0.000
Fanconi 0.000
sudden infant death syndrome 0.000
hyperprolactinemia 0.000
cerebral palsy 0.000
cerebral ischemia 0.000
volvulus 0.000
Creutzfeldt-Jakob disease 0.000
transient ischemic attack 0.000
carpal tunnel syndrome 0.000
amyotrophic lateral sclerosis 0.000
HCG 0.000
primary biliary cirrhosis 0.000
metabolic disorder 0.000
renal cancer 0.000
SLE 0.000
atrioventricular block 0.000
sickle cell disease 0.000
leiomyoma 0.000
myopia 0.000
trisomy 0.000
confusion 0.000
Pituitary 0.000
amnesia 0.000
tuberous sclerosis 0.000
parvovirus 0.000
retinal detachment 0.000
delirium 0.000
proteinuria 0.000
congestive heart failure 0.000
CTX 0.000
rubella 0.000
autoimmune disease 0.000
respiratory failure 0.000
ventricular septal defect 0.000
erectile dysfunction 0.000
Pancreas 0.000
toxoplasmosis 0.000
prematurity 0.000
hypothyroidism 0.000
Pancreas 0.000
renal disease 0.000
malabsorption 0.000
hyperglycemia 0.000
ischemia 0.000
hallucinations 0.000
aspergillosis 0.000
renal failure 0.000
autism 0.000
glioblastoma 0.000
goiter 0.000
WT1 0.000
meningioma 0.000
peptic ulcer 0.000
diabetic retinopathy 0.000
Chagas 0.000
more...
Symptom
External ophthalmoplegia 0.000
ophthalmoplegia 0.000
Ataxic 0.000
ataxia 0.000
visual hallucination 0.000
myoclonus 0.000
seizures 0.000
weakness 0.000
headache 0.000
cerebellar ataxia 0.000
Neurologic symptoms 0.000
hemiplegia 0.000
vomiting 0.000
syncopal episodes 0.000
Decreased activity 0.000
clumsiness 0.000
ketonuria 0.000
tonic-clonic seizure 0.000
dysarthria 0.000
hypotonia 0.000
partial seizure 0.000
muscle cramps 0.000
neurological disability 0.000
dysesthesia 0.000
spasticity 0.000
catatonia 0.000
myalgia 0.000
incoordination 0.000
chorea 0.000
dystonia 0.000
paresthesia 0.000
ENT 0.000
pallor 0.000
nausea 0.000
paraparesis 0.000
tinnitus 0.000
constipation 0.000
numbness 0.000
anesthesia 0.000
sleepiness 0.000
fatigue 0.000
hepatomegaly 0.000
paresis 0.000
vertigo 0.000
tremor 0.000
angina 0.000
dizziness 0.000
erythema 0.000
chest pain 0.000
hypothermia 0.000
dyspnea 0.000
analgesia 0.000
collapse 0.000
abdominal pain 0.000
pain 0.000
Drug
Arginine hydrochloride 0.000
Sodium dichloroacetate 0.000
R-gene 0.000
Gastro 0.000
NADH 0.000
EPI 0.000
PFA 0.000
CSF 0.000
niacin 0.000
MDS 0.000
Fragment 0.000
AZT 0.000
Fluorescein 0.000
Growth hormone 0.000
AZT 0.000
Growth hormone 0.000
MRC 0.000
Glucagon 0.000
Fluorescein 0.000
ENT 0.000
CTX 0.000
CTX 0.000
ROS 0.000
ABC 0.000
lysine 0.000
citric acid 0.000
CTX 0.000
ascorbate 0.000
Asn 0.000
vitamin E 0.000
Dermatol 0.000
Cardiovasc 0.000
Enzyme
complex I 0.001
pyruvate dehydrogenase 0.000
cytochrome oxidase 0.000
leucyl-tRNA synthetase 0.000
succinate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
pyruvate dehydrogenase 0.000
LasR 0.000
HVS 0.000
alpha-ketoglutarate dehydrogenase 0.000
branched-chain alpha-keto acid dehydrogenase 0.000
biotinidase 0.000
thymidine phosphorylase 0.000
fumarase 0.000
argininosuccinate synthetase 0.000
citrate synthase 0.000
succinic dehydrogenase 0.000
diaphorase 0.000
NADH dehydrogenase 0.000
CPT 0.000
acyl-CoA dehydrogenase 0.000
pyruvate carboxylase 0.000
aconitase 0.000
ATP synthase 0.000
glutamate decarboxylase 0.000
phosphoglycerate kinase 0.000
CPR 0.000
diaphorase 0.000
acetyl-CoA carboxylase 0.000
creatine kinase 0.000
thyroid peroxidase 0.000
CPT 0.000
CPT 0.000
NADPH-diaphorase 0.000
endonuclease 0.000
ceruloplasmin 0.000
phosphorylase 0.000
cholinesterase 0.000
phosphoinositide 3-kinase 0.000
DNA polymerase 0.000
superoxide dismutase 0.000
acetylcholinesterase 0.000
AMP-activated protein kinase 0.000
NO synthase 0.000
ATPase 0.000
RNase 0.000
calcineurin 0.000
RNase 0.000
glutathione peroxidase 0.000
catalase 0.000
thrombin 0.000
caspase-3 0.000
mitogen-activated protein kinase 0.000
Compound
leucine 0.000
DNA 0.000
coenzyme Q10 0.000
4-oxobutanoic acid 0.000
CoQ 0.000
ASK 0.000
CIT 0.000
Coenzyme Q10 0.000
MSL 0.000
Edaravone 0.000
COX 0.000
D-glucuronate 0.000
N-acetylaspartate 0.000
Fumarate 0.000
arginine 0.000
Valproic acid 0.000
ubiquinone 0.000
MPT 0.000
DETA 0.000
Taurine 0.000
Deoxyribonucleic acid 0.000
EPC 0.000
Dichloroacetate 0.000
NADH 0.000
ATP 0.000
lysine 0.000
DCA 0.000
DCA 0.000
uridine 0.000
Linezolid 0.000
Rotenone 0.000
Pyruvate 0.000
Polypeptide 0.000
CAA 0.000
Xenon 0.000
Creatine 0.000
nitric oxide 0.000
phosphocreatine 0.000
Argentine 0.000
SO3 0.000
Valproic acid 0.000
L-carnitine 0.000
2-nonenal 0.000
COI 0.000
nicotinamide 0.000
tungsten 0.000
His 0.000
Cytochrome c 0.000
DOCA 0.000
oxygen 0.000
Glycogen 0.000
Leucine 0.000
glucose 0.000
Dec 0.000
AAA 0.000
Lactate 0.000
Guo 0.000
IMP 0.000
CPT 0.000
NAD 0.000
AZT 0.000
8-OHdG 0.000
Rapamycin 0.000
CPT 0.000
succinic acid 0.000
Glucagon 0.000
Tyrosine 0.000
NAD 0.000
Thrombin 0.000
ANA 0.000
ANA 0.000
Guo 0.000
H2O2 0.000
Neuronal 0.000
MPTP 0.000
GSSG 0.000
butyric acid 0.000
glutamate 0.000
ADP 0.000
ADP 0.000
adenylate 0.000
butyric acid 0.000
PAS 0.000
valine 0.000
ADP 0.000
TSH 0.000
butyric acid 0.000
DTPA 0.000
ammonium 0.000
2-oxoglutarate 0.000
phosphorus 0.000
dUTP 0.000
alanine 0.000
Diabetol 0.000
Clin 0.000
L-DOPA 0.000
creatinine 0.000
Panam 0.000
CTX 0.000
Diabetol 0.000
N-acetylcysteine 0.000
threonine 0.000
hydroxide 0.000
sodium 0.000
glutamine 0.000
calcium 0.000
Off 0.000
Cereb 0.000
Gly 0.000
CoA 0.000
urea 0.000
chlorine 0.000
aldehyde 0.000
bromide 0.000
ACTH 0.000
Phe 0.000
aldehyde 0.000
methionine 0.000
MTT 0.000
Asp 0.000
acetic acid 0.000
nitrogen 0.000
glycerol 0.000
GSH 0.000
GSH 0.000
NH2 0.000
hydrogen 0.000
Cardiol 0.000
phosphate 0.000
CO2 0.000
copper 0.000
tyrosine 0.000
iron 0.000
ethanol 0.000