Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0162671 (MELAS)
 587 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MELAS 455
tRNA 133
MERRF 108
Mol 47
Sep 45
MRI 43
cytochrome c oxidase 32
LHON 30
NARP 28
ATP 26
insulin 18
She 17
CADASIL 13
TL1A 12
cytochrome 11
ND5 11
NADH 10
pyruvate dehydrogenase complex 10
CSF 9
MNGIE 9
more...
Disease
MELAS 587
MELAS 458
stroke 311
lactic acidosis 297
encephalopathy 203
mitochondrial myopathy 144
mitochondrial encephalomyopathy 112
MERRF 108
diabetes 89
mitochondrial disease 88
Leigh syndrome 62
epilepsy 58
myopathy 56
deafness 51
Kearns-Sayre syndrome 50
Leber's hereditary optic neuropathy 43
migraine 30
dementia 29
cardiomyopathy 27
Chronic progressive external ophthalmoplegia 25
more...
Symptom
seizures 54
headache 39
weakness 33
ataxia 30
ophthalmoplegia 27
vomiting 15
myoclonus 12
anesthesia 8
cerebellar ataxia 8
fatigue 5
nausea 5
hemiplegia 5
hypotonia 5
spasticity 4
dysarthria 4
dystonia 3
visual hallucination 3
myalgia 3
angina 2
constipation 2
more...
Drug
NADH 10
CSF 9
lysine 4
Gastro 2
niacin 2
ENT 2
Dermatol 2
EPI 2
ascorbate 2
ROS 2
MDS 1
Cardiovasc 1
MRC 1
R-gene 1
Arginine hydrochloride 1
Fluorescein 1
citric acid 1
ABC 1
AZT 1
CTX 1
more...
Enzyme
complex I 52
pyruvate dehydrogenase 16
cytochrome oxidase 16
succinate dehydrogenase 14
pyruvate dehydrogenase 8
pyruvate dehydrogenase 8
diaphorase 4
citrate synthase 4
creatine kinase 4
superoxide dismutase 4
LasR 3
CPT 3
ATPase 3
endonuclease 3
ATP synthase 3
alpha-ketoglutarate dehydrogenase 3
fumarase 2
mitogen-activated protein kinase 2
acetylcholinesterase 2
succinic dehydrogenase 2
more...
Compound
DNA 227
leucine 97
Dec 55
arginine 28
oxygen 26
Clin 26
ATP 26
glucose 21
lysine 20
nitric oxide 17
His 12
NADH 10
coenzyme Q10 10
calcium 9
sodium 9
uridine 7
CIT 7
ubiquinone 6
CoQ 6
glutamate 6
more...