Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0162473 (Frey)
2,599 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 173
Mol 83
opioid receptor 78
TNF 74
cytokine 59
substance P 49
glial fibrillary acidic protein 44
NMDA receptor 43
tumor necrosis factor 42
axonal 39
bradykinin 38
calcitonin 35
TRPV1 34
GABA 32
IL-6 31
ATP 28
brain-derived neurotrophic factor 28
nerve growth factor 26
DRG 22
nitric oxide synthase 21
transient receptor potential vanilloid 1 20
nov 20
inducible nitric oxide synthase 19
p38 19
COX-2 18
CFA 18
cyclooxygenase-2 18
myeloperoxidase 18
ERK 17
interleukin-6 17
hairy 17
lipopolysaccharide 16
P2X 16
superoxide dismutase 16
Iba1 16
extracellular signal-regulated kinase 15
ANOVA 15
IL-10 15
calcium channel 15
dynorphin 14
ERK1 14
5-hydroxytryptamine 14
insulin 13
CB1 13
GSH 13
CD11b 13
CB2 12
MAPK 12
T10 12
T13 12
TRPA1 12
HT3 12
gut 12
NMR 11
Mot 11
chemokine 11
STZ 11
Walker 11
glutamate receptor 11
TLR4 10
c-fos 10
CGRP 10
OFQ 10
PBS 10
p65 10
cyclooxygenase 10
mast cell 10
oxytocin 9
P2X3 9
MRI 9
5-HT3 receptor 9
cannabinoid receptor 9
SNL 9
5-HT1A 9
NR2B 9
collagen 9
CO2 9
SNS 9
catalase 8
cholecystokinin 8
more...
Disease
Frey 2599
cold 253
chronic pain 192
neuropathy 126
cancer 112
peripheral neuropathy 100
tumor 76
chronic pancreatitis 72
diabetes 72
depression 66
diabetic neuropathy 48
osteoarthritis 36
adenoma 29
facial palsy 28
migraine 25
carcinoma 24
arthritis 24
mononeuropathy 21
fibromyalgia 21
stroke 20
Mycoplasma 20
hyperglycemia 19
pancreatitis 19
ischemia 18
nerve lesion 16
trigeminal neuralgia 16
bone cancer 15
Evans 15
NAME 14
colitis 13
Parkinson's disease 13
pruritus 13
GSH 13
cystitis 12
Gustatory sweating 12
interstitial cystitis 12
hypertension 11
colorectal cancer 9
adenocarcinoma 9
rubella 8
postherpetic neuralgia 8
regional pain syndrome 8
herpes zoster 8
sensory neuropathy 8
neuroma 8
Diabetic neuropathy 7
food allergy 7
multiple sclerosis 7
rheumatoid arthritis 7
cognitive impairment 7
polyneuropathy 7
dysphagia 6
tumor growth 6
sialadenitis 6
HIV 6
causalgia 6
cornea 6
monoarthritis 6
ash 6
Warthin's tumor 6
squamous cell carcinoma 6
SEM 5
Bladder 5
Nose 5
Blocking 5
obesity 5
cholestasis 5
encephalomyelitis 5
breast cancer 5
anxiety disorders 5
acute pancreatitis 5
benign tumor 5
Syndrome 5
Bladder 5
pancreatic cancer 5
cerebral ischemia 5
Bladder 5
catalepsy 5
parotitis 5
radiculopathy 5
more...
Symptom
pain 1508
analgesia 123
anesthesia 84
Neuropathic pain 78
flushing 43
acute pain 26
myalgia 23
cancer pain 21
headache 19
weakness 19
paresis 19
functional recovery 18
numbness 15
paresthesia 15
abdominal pain 14
orofacial pain 14
discomfort 13
discomfort 13
arthralgia 12
bladder pain 12
pelvic pain 11
erythema 11
hyperesthesia 10
back pain 10
low back pain 9
bone pain 9
facial pain 9
fatigue 8
Visceral pain 6
dysesthesia 6
seizures 6
dystonia 6
nausea 5
sciatica 5
Postoperative pain 5
Inflammatory pain 5
tremor 5
ENT 5
Central post-stroke pain 4
diarrhea 4
incoordination 4
motor symptom 4
spasm 4
tingling 4
Peripheral neuropathic pain 4
cough 4
distraction 4
rhinorrhea 4
blepharospasm 4
Radicular pain 3
hypothermia 3
Mechanical pain 3
excessive sweating 3
insomnia 3
sleepiness 3
vomiting 3
neck pain 2
agitation 2
epigastric pain 2
Welt 2
Grimace 2
photophobia 2
constipation 2
urinary frequency 2
dizziness 2
nerve pain 2
vestibulitis 2
Wind 2
skin pain 2
nausea and vomiting 2
tinnitus 2
Chronic pelvic pain syndrome 2
ataxia 2
knee pain 2
abnormal gait 2
acute stress 2
neuralgia 2
skin damage 2
hypalgesia 1
Throbbing pain 1
more...
Drug
Gabapentin 22
Oxaliplatin 21
Dermatol 16
lysine 13
SNL 9
nitroglycerin 9
Pregabalin 8
Duloxetine 7
Domperidone 7
Portal 6
caffeine 6
CSF 5
Histamine 5
ENT 5
p75 4
Bupivacaine 4
ICI 4
Ketorolac 3
NADH 3
-deoxyadenosine 3
Dipyrone 3
pyridoxal phosphate 3
Indomethacin 3
Nephron 3
Propentofylline 3
vitamin E 3
IL-1ra 3
Horizon 2
Reserpine 2
Nitric Oxide 2
Dizocilpine maleate 2
Ethanol 2
Clonidine 2
Gelatin 2
Botox 2
Vicryl 2
PMPA 2
Amiloride 2
DBS 2
Donepezil 2
Amiloride 2
Elcatonin 2
Fraction 2
Reboxetine 2
Tapentadol 2
Vitamin B12 2
TRM 2
niacin 1
Metrizamide 1
Proglumide 1
Camostat mesilate 1
Pyridostigmine bromide 1
Nitecapone 1
Carbenoxolone 1
EHDP 1
Frontal 1
Codeine 1
Naropin 1
Parecoxib 1
Bayer 1
Xylocaine 1
Fluorescein 1
Propofol 1
ETA 1
Photofrin 1
Tenoxicam 1
Vinpocetine 1
Pyridostigmine bromide 1
Gel 1
Bromelain 1
L-Ser 1
Nimesulide 1
Mirtazapine 1
Phentolamine 1
BOTOX 1
Kenyan 1
Ezlopitant 1
Teriparatide 1
Tramal 1
Ulinastatin 1
more...
Enzyme
mitogen-activated protein kinase 43
protein kinase 27
peroxidase 21
ERK 20
superoxide dismutase 16
protein kinase C 15
phospholipase A2 10
NO synthase 9
catalase 9
hydrogenase 7
hydrogenase 7
glutathione peroxidase 7
MEK 7
chymotrypsin 6
lysine 2,3-aminomutase 6
guanylate cyclase 6
CaMKII 5
phospholipase C 5
NOS 5
PKG 5
ATPase 5
reverse transcriptase 4
monoamine oxidase 4
heme oxygenase 4
trypsin 4
TSA 4
elastase 3
caspase-1 3
thrombin 3
phosphodiesterase 3
pyruvate formate-lyase 3
tryptase 3
leucine aminopeptidase 3
focal adhesion kinase 3
acetylcholinesterase 3
15-lipoxygenase 3
collagenase 3
4-epimerase 3
PARP 3
SPC 3
DNA polymerase 3
caspase-3 3
aspartate aminotransferase 3
tyrosine hydroxylase 3
CPS 2
ACS 2
RNA polymerase 2
calcineurin 2
botulinum neurotoxin 2
alanine aminotransferase 2
GD3 synthase 2
aminopeptidase I 2
kinesin 2
AMPK 2
chondroitinase 2
chondroitinase 2
hyaluronidase 2
glutamate decarboxylase 2
arginase 2
neutral sphingomyelinase 2
alkaline phosphatase 2
PRE 2
papain 2
endonuclease 2
renin 2
PFL activase 2
kallikrein 2
phosphatidylinositol 3-kinase 2
aldose reductase 2
ACE 2
tissue kallikrein 2
lysozyme 1
neutrophil elastase 1
proteasome 1
neuraminidase 1
adenylate cyclase 1
fatty acid desaturase 1
SPT 1
glyceraldehyde-3-phosphate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
more...
Compound
Dec 191
acetone 112
TNF 74
water 70
calcium 63
glutamate 60
5-HT 49
nitric oxide 48
sodium 47
Clin 45
iodine 39
oxygen 38
Morphine 38
arginine 36
glucose 35
GABA 33
GABA 33
NMDA 30
hydrogen 29
ATP 28
DNA 28
noradrenaline 25
acetic acid 23
Paclitaxel 23
Capsaicin 20
phosphate 20
His 19
serine 16
sulfate 16
Gly 16
lysine 16
CO2 15
tyrosine 15
iron 14
GSH 13
GSH 13
STZ 13
T13 12
Vincristine 12
ethanol 12
T10 12
cGMP 12
cAMP 11
alanine 11
galactose 11
cysteine 11
potassium 10
salt 10
gamma-aminobutyric acid 10
Neuronal 10
AMPA 10
leucine 9
Asp 9
acetate 9
PGE 9
DMSO 9
UDP-glucose 8
Substance P 8
PGE2 8
tryptophan 8
Tramadol 8
NH2 8
A 1 7
HCl 7
Salt 7
Glutamate 7
DAMGO 7
threonine 7
Lidocaine 7
UDP 7
UMP 7
Phe 6
caffeine 6
AEA 6
CPA 6
nickel 6
urea 6
Ketamine 6
DDP 6
adenosylmethionine 6
more...