Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0162473 (
Frey
)
2,599
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
173
Mol
83
opioid receptor
78
TNF
74
cytokine
59
substance P
49
glial fibrillary acidic protein
44
NMDA receptor
43
tumor necrosis factor
42
axonal
39
bradykinin
38
calcitonin
35
TRPV1
34
GABA
32
IL-6
31
ATP
28
brain-derived neurotrophic factor
28
nerve growth factor
26
DRG
22
nitric oxide synthase
21
transient receptor potential vanilloid 1
20
nov
20
inducible nitric oxide synthase
19
p38
19
COX-2
18
CFA
18
cyclooxygenase-2
18
myeloperoxidase
18
ERK
17
interleukin-6
17
hairy
17
lipopolysaccharide
16
P2X
16
superoxide dismutase
16
Iba1
16
extracellular signal-regulated kinase
15
ANOVA
15
IL-10
15
calcium channel
15
dynorphin
14
ERK1
14
5-hydroxytryptamine
14
insulin
13
CB1
13
GSH
13
CD11b
13
CB2
12
MAPK
12
T10
12
T13
12
TRPA1
12
HT3
12
gut
12
NMR
11
Mot
11
chemokine
11
STZ
11
Walker
11
glutamate receptor
11
TLR4
10
c-fos
10
CGRP
10
OFQ
10
PBS
10
p65
10
cyclooxygenase
10
mast cell
10
oxytocin
9
P2X3
9
MRI
9
5-HT3 receptor
9
cannabinoid receptor
9
SNL
9
5-HT1A
9
NR2B
9
collagen
9
CO2
9
SNS
9
catalase
8
cholecystokinin
8
more...
Disease
Frey
2599
cold
253
chronic pain
192
neuropathy
126
cancer
112
peripheral neuropathy
100
tumor
76
chronic pancreatitis
72
diabetes
72
depression
66
diabetic neuropathy
48
osteoarthritis
36
adenoma
29
facial palsy
28
migraine
25
carcinoma
24
arthritis
24
mononeuropathy
21
fibromyalgia
21
stroke
20
Mycoplasma
20
hyperglycemia
19
pancreatitis
19
ischemia
18
nerve lesion
16
trigeminal neuralgia
16
bone cancer
15
Evans
15
NAME
14
colitis
13
Parkinson's disease
13
pruritus
13
GSH
13
cystitis
12
Gustatory sweating
12
interstitial cystitis
12
hypertension
11
colorectal cancer
9
adenocarcinoma
9
rubella
8
postherpetic neuralgia
8
regional pain syndrome
8
herpes zoster
8
sensory neuropathy
8
neuroma
8
Diabetic neuropathy
7
food allergy
7
multiple sclerosis
7
rheumatoid arthritis
7
cognitive impairment
7
polyneuropathy
7
dysphagia
6
tumor growth
6
sialadenitis
6
HIV
6
causalgia
6
cornea
6
monoarthritis
6
ash
6
Warthin's tumor
6
squamous cell carcinoma
6
SEM
5
Bladder
5
Nose
5
Blocking
5
obesity
5
cholestasis
5
encephalomyelitis
5
breast cancer
5
anxiety disorders
5
acute pancreatitis
5
benign tumor
5
Syndrome
5
Bladder
5
pancreatic cancer
5
cerebral ischemia
5
Bladder
5
catalepsy
5
parotitis
5
radiculopathy
5
more...
Symptom
pain
1508
analgesia
123
anesthesia
84
Neuropathic pain
78
flushing
43
acute pain
26
myalgia
23
cancer pain
21
headache
19
weakness
19
paresis
19
functional recovery
18
numbness
15
paresthesia
15
abdominal pain
14
orofacial pain
14
discomfort
13
discomfort
13
arthralgia
12
bladder pain
12
pelvic pain
11
erythema
11
hyperesthesia
10
back pain
10
low back pain
9
bone pain
9
facial pain
9
fatigue
8
Visceral pain
6
dysesthesia
6
seizures
6
dystonia
6
nausea
5
sciatica
5
Postoperative pain
5
Inflammatory pain
5
tremor
5
ENT
5
Central post-stroke pain
4
diarrhea
4
incoordination
4
motor symptom
4
spasm
4
tingling
4
Peripheral neuropathic pain
4
cough
4
distraction
4
rhinorrhea
4
blepharospasm
4
Radicular pain
3
hypothermia
3
Mechanical pain
3
excessive sweating
3
insomnia
3
sleepiness
3
vomiting
3
neck pain
2
agitation
2
epigastric pain
2
Welt
2
Grimace
2
photophobia
2
constipation
2
urinary frequency
2
dizziness
2
nerve pain
2
vestibulitis
2
Wind
2
skin pain
2
nausea and vomiting
2
tinnitus
2
Chronic pelvic pain syndrome
2
ataxia
2
knee pain
2
abnormal gait
2
acute stress
2
neuralgia
2
skin damage
2
hypalgesia
1
Throbbing pain
1
more...
Drug
Gabapentin
22
Oxaliplatin
21
Dermatol
16
lysine
13
SNL
9
nitroglycerin
9
Pregabalin
8
Duloxetine
7
Domperidone
7
Portal
6
caffeine
6
CSF
5
Histamine
5
ENT
5
p75
4
Bupivacaine
4
ICI
4
Ketorolac
3
NADH
3
-deoxyadenosine
3
Dipyrone
3
pyridoxal phosphate
3
Indomethacin
3
Nephron
3
Propentofylline
3
vitamin E
3
IL-1ra
3
Horizon
2
Reserpine
2
Nitric Oxide
2
Dizocilpine maleate
2
Ethanol
2
Clonidine
2
Gelatin
2
Botox
2
Vicryl
2
PMPA
2
Amiloride
2
DBS
2
Donepezil
2
Amiloride
2
Elcatonin
2
Fraction
2
Reboxetine
2
Tapentadol
2
Vitamin B12
2
TRM
2
niacin
1
Metrizamide
1
Proglumide
1
Camostat mesilate
1
Pyridostigmine bromide
1
Nitecapone
1
Carbenoxolone
1
EHDP
1
Frontal
1
Codeine
1
Naropin
1
Parecoxib
1
Bayer
1
Xylocaine
1
Fluorescein
1
Propofol
1
ETA
1
Photofrin
1
Tenoxicam
1
Vinpocetine
1
Pyridostigmine bromide
1
Gel
1
Bromelain
1
L-Ser
1
Nimesulide
1
Mirtazapine
1
Phentolamine
1
BOTOX
1
Kenyan
1
Ezlopitant
1
Teriparatide
1
Tramal
1
Ulinastatin
1
more...
Enzyme
mitogen-activated protein kinase
43
protein kinase
27
peroxidase
21
ERK
20
superoxide dismutase
16
protein kinase C
15
phospholipase A2
10
NO synthase
9
catalase
9
hydrogenase
7
hydrogenase
7
glutathione peroxidase
7
MEK
7
chymotrypsin
6
lysine 2,3-aminomutase
6
guanylate cyclase
6
CaMKII
5
phospholipase C
5
NOS
5
PKG
5
ATPase
5
reverse transcriptase
4
monoamine oxidase
4
heme oxygenase
4
trypsin
4
TSA
4
elastase
3
caspase-1
3
thrombin
3
phosphodiesterase
3
pyruvate formate-lyase
3
tryptase
3
leucine aminopeptidase
3
focal adhesion kinase
3
acetylcholinesterase
3
15-lipoxygenase
3
collagenase
3
4-epimerase
3
PARP
3
SPC
3
DNA polymerase
3
caspase-3
3
aspartate aminotransferase
3
tyrosine hydroxylase
3
CPS
2
ACS
2
RNA polymerase
2
calcineurin
2
botulinum neurotoxin
2
alanine aminotransferase
2
GD3 synthase
2
aminopeptidase I
2
kinesin
2
AMPK
2
chondroitinase
2
chondroitinase
2
hyaluronidase
2
glutamate decarboxylase
2
arginase
2
neutral sphingomyelinase
2
alkaline phosphatase
2
PRE
2
papain
2
endonuclease
2
renin
2
PFL activase
2
kallikrein
2
phosphatidylinositol 3-kinase
2
aldose reductase
2
ACE
2
tissue kallikrein
2
lysozyme
1
neutrophil elastase
1
proteasome
1
neuraminidase
1
adenylate cyclase
1
fatty acid desaturase
1
SPT
1
glyceraldehyde-3-phosphate dehydrogenase
1
glyceraldehyde-3-phosphate dehydrogenase
1
more...
Compound
Dec
191
acetone
112
TNF
74
water
70
calcium
63
glutamate
60
5-HT
49
nitric oxide
48
sodium
47
Clin
45
iodine
39
oxygen
38
Morphine
38
arginine
36
glucose
35
GABA
33
GABA
33
NMDA
30
hydrogen
29
ATP
28
DNA
28
noradrenaline
25
acetic acid
23
Paclitaxel
23
Capsaicin
20
phosphate
20
His
19
serine
16
sulfate
16
Gly
16
lysine
16
CO2
15
tyrosine
15
iron
14
GSH
13
GSH
13
STZ
13
T13
12
Vincristine
12
ethanol
12
T10
12
cGMP
12
cAMP
11
alanine
11
galactose
11
cysteine
11
potassium
10
salt
10
gamma-aminobutyric acid
10
Neuronal
10
AMPA
10
leucine
9
Asp
9
acetate
9
PGE
9
DMSO
9
UDP-glucose
8
Substance P
8
PGE2
8
tryptophan
8
Tramadol
8
NH2
8
A 1
7
HCl
7
Salt
7
Glutamate
7
DAMGO
7
threonine
7
Lidocaine
7
UDP
7
UMP
7
Phe
6
caffeine
6
AEA
6
CPA
6
nickel
6
urea
6
Ketamine
6
DDP
6
adenosylmethionine
6
more...