Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0162473 (Frey)
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Human Gene/Protein
ARHA 12.0
Galactose-1-phosphate uridylyltransferase 11.8
NEDD8-specific protease 11.0
deleted in liver cancer 2 10.8
cerebellin 4 10.8
GCH1 protein 10.6
CBLN2 10.4
Rho guanine nucleotide exchange factor 10 10.4
fragile histidine triad protein 10.3
G protein-coupled receptor 35 9.9
galanin receptor type 2 9.7
Acid-sensing ion channel 3 9.6
CHAR 9.6
SNL 9.5
LAP4 9.3
ST8Sia VI 9.2
N-acyl phosphatidylethanolamine phospholipase D 9.0
UNC5H2 9.0
IL6 protein 9.0
Delta(5)-3-ketosteroid isomerase 8.8
p32 protein 8.8
SLC17A9 8.8
Calpain-2 8.8
5-HT5A 8.7
LPP1 8.7
GCPS 8.5
ARHGEF10 8.5
CYP4F22 8.4
NPH1 8.3
SLC9A6 8.2
BITE 8.1
ASIC3 8.0
PDE7A 8.0
T13 8.0
Cannabinoid receptor 1 8.0
NHE6 7.9
cerebellin 7.9
QRFP 7.9
Voltage-gated sodium channel 7.9
oncostatin M receptor 7.8
muscarinic M2 receptor 7.8
26RFa 7.7
GPR103 7.7
bradykinin B1 receptor 7.7
uroplakin III 7.7
UDP-galactose 4-epimerase 7.7
ionized calcium-binding adapter molecule 7.6
ankyrin 1 7.6
orphan G-protein coupled receptor 7.6
ACAA 7.6
NALP1 7.6
GPR3 7.6
Nav1.7 7.6
p75 TNF receptor 7.5
Iba1 7.5
nSMase 7.5
mGlu7 7.5
uroplakin II 7.5
OX2 7.5
Pannexin-1 7.5
GPR7 7.5
Annexin I 7.4
P2X purinoceptor 7.4
delta-catenin 7.4
P2X3 7.4
GD3 synthase 7.4
GlyT1 7.3
MIP2 7.3
claudin 2 7.3
HYL 7.3
DEN1 7.2
Cyclooxygenase-1 7.2
TRPV1 7.2
GlyT2 7.2
KCC4 7.2
RAGE protein 7.2
galactose-1-phosphate uridylyltransferase 7.2
ASIC1 7.2
NLRP3 protein 7.2
interleukin-1 receptor-associated kinase 1 7.1
TMEM16B 7.1
NFIA 7.1
transient receptor potential vanilloid 1 7.1
periaxin 7.1
RECA 7.1
CT3 7.1
TRPA1 7.0
Cav3.3 7.0
SNS 7.0
BGT1 7.0
colony stimulating factor 1 receptor 7.0
CX3C chemokine receptor 1 7.0
LIG 7.0
zinc transporter 3 7.0
CFA 6.9
Nav1.3 6.9
Neuropeptide W 6.9
mPGES-2 6.9
Trif 6.9
ORL1 6.9
DRG 6.9
receptor activity-modifying protein 1 6.9
F13A 6.8
RIPK2 6.8
proteinase-activated receptor-2 6.8
ST19 6.8
BTD 6.8
5-HT7 6.8
FMI 6.7
calcium-independent phospholipase A2 6.7
TTL 6.7
caveolin-3 6.7
neurokinin 1 receptor 6.6
GBP 6.6
OFQ 6.6
Optineurin 6.6
TTD 6.6
iPLA2 6.6
inhibitory glycine receptor 6.5
OX2R 6.5
VGLUT1 6.5
mGlu3 6.5
Cav2.2 6.5
FM3 6.5
CNI 6.5
glutamate carboxypeptidase II 6.5
FAAH 6.4
PSAP 6.4
CPN 6.4
opioid receptor 6.4
B1R 6.4
Ras inhibitor 6.4
ubiquitin carboxyl-terminal hydrolase 6.3
thioredoxin interacting protein 6.3
COX IV 6.3
FMT 6.3
IBP 6.3
SYM 6.3
Cav3.1 6.3
DHPR 6.3
vesicular glutamate transporter 1 6.2
CCR2B 6.2
CHM 6.2
CRF1 6.2
PRSS1 6.2
CCL7 6.2
nuclear pore protein 6.2
IRAK-1 6.1
guanine nucleotide-binding regulatory protein 6.1
GRK6 6.1
GCH1 6.1
INI 6.1
Cav3.2 6.1
melastatin 6.1
prodynorphin 6.1
ATF3 6.1
GPR40 6.1
TKR 6.0
SIII 6.0
CGRP 6.0
more...
Disease
Frey 13.6
Gustatory sweating 12.3
Generalized hyperhidrosis 12.3
Non-bacterial prostatitis 12.0
Chronic sialadenitis 11.3
Bile duct stricture 11.0
Painful Bladder Syndrome 11.0
Hypoglucagonemia 10.8
Primary focal hyperhidrosis 10.3
Goldscheider 10.3
Biliary stricture 10.2
CHAR 10.1
Neonatal anoxia 9.8
LI3 9.7
Vulvar vestibulitis 9.6
Colonic obstruction 9.6
Pancreatic ascites 9.5
IMD1 9.4
Ross syndrome 9.3
Lupus erythematosus profundus 8.8
alcoholic neuropathy 8.5
mononeuropathy 8.4
NINA 8.3
Sluder 8.0
causalgia 8.0
Diabetic neuropathy 7.9
Gender dysphoria 7.7
Warthin's tumor 7.6
Facial palsy 7.5
bone cancer 7.5
Autotomy 7.5
nerve lesion 7.4
diabetic neuropathy 7.4
megalocytosis 7.2
monoarthritis 7.2
autonomic disorder 7.1
Lumbar disc herniation 7.1
chronic pancreatitis 6.9
chronic pain 6.9
sialolithiasis 6.9
Pleomorphic adenoma 6.9
peripheral neuropathy 6.9
Greig cephalopolysyndactyly syndrome 6.9
interstitial cystitis 6.8
Pancreatic fistula 6.8
BPS 6.7
Duodenum 6.6
Duodenum 6.6
Chronic migraine 6.6
Parotid gland 6.6
GDD 6.5
pompholyx 6.5
regional pain syndrome 6.5
facial palsy 6.4
Complex regional pain syndrome 6.3
Schmitz 6.3
parotitis 6.3
MPE 6.3
trigeminal neuralgia 6.2
Fibrosarcoma 6.2
pancreatic fibrosis 6.1
neuropathy 6.1
neurofibrosarcoma 6.0
postherpetic neuralgia 6.0
sialadenitis 6.0
Dedifferentiation 6.0
macromastia 6.0
neuroma 6.0
acute arthritis 5.9
fibromyalgia 5.8
Chronic prostatitis 5.8
Recurrent disease 5.8
bone neoplasm 5.8
sensory neuropathy 5.8
complement deficiency 5.7
diabetic hyperglycemia 5.7
denticles 5.7
Laennec 5.7
vascular headache 5.6
Temporomandibular Disorders 5.6
xerophthalmia 5.6
Ludwig 5.6
IS3 5.6
Tauopathies 5.5
acute cystitis 5.5
herniated disc 5.5
evaluable disease 5.4
NPHP1 5.3
Horner syndrome 5.3
degenerative disc disease 5.2
TMD 5.2
Abdomen 5.2
cystitis 5.1
cold 5.1
pancreatic cyst 5.0
harlequin 5.0
bruxism 5.0
Hailey-Hailey disease 5.0
TMD 4.9
coryza 4.9
galactosemia 4.9
entropion 4.9
Horton 4.9
speech disorder 4.9
plexiform neurofibroma 4.9
Vesicular stomatitis 4.9
skin hypersensitivity 4.9
MSA 4.9
familial dysautonomia 4.8
Opiates 4.8
gastrointestinal dysfunction 4.8
PSP 4.8
catalepsy 4.7
Li-Fraumeni syndrome 4.6
Lower limb 4.6
radiculopathy 4.6
anhidrosis 4.6
Bladder 4.6
Bladder 4.6
Bladder 4.6
coxarthrosis 4.6
stuttering 4.5
dysphonia 4.5
dental calculus 4.5
carcinoma of the pancreas 4.5
Buruli ulcer 4.5
food allergy 4.4
PMT 4.4
Ductal 4.4
Habituation 4.4
sensory disturbance 4.3
Bradley 4.3
pulpitis 4.3
herpes zoster 4.3
abnormal involuntary movements 4.3
Hereditary angioedema 4.2
migraine 4.2
prostatitis 4.2
EDA 4.2
Dystonia 4.1
cutis laxa 4.1
tension headache 4.1
adenoma 4.1
Mycoplasma 4.1
TCD 4.0
rubella 4.0
Larsen 4.0
Wenckebach 3.9
Evans 3.9
Benson 3.9
biliary obstruction 3.9
syringomyelia 3.9
pancreatitis 3.9
benign tumor 3.8
hidradenitis 3.8
dysautonomia 3.7
homocystinuria 3.7
NAME 3.7
TMJ 3.7
Tumour necrosis 3.7
more...
Symptom
Throbbing pain 12.0
Abnormal sensation 12.0
Cutaneous hyperalgesia 12.0
Central post-stroke pain 10.8
Pancreatic pain 10.8
Central pain syndrome 10.8
Peripheral neuropathic pain 10.6
Incisional pain 10.3
Mechanical pain 10.1
Radiating pain 10.0
Chronic pelvic pain syndrome 9.7
Radicular pain 9.7
Inflammatory pain 9.7
Neuropathic pain 9.4
Burning pain 9.3
Visceral pain 9.3
Lower abdominal pain 9.1
Other pain 8.9
UTI symptoms 8.6
bladder pain 8.6
Grimace 8.5
Intractable pain 8.5
skin pain 8.3
sialectasis 8.1
Central pain 7.9
hyperesthesia 7.9
nerve pain 7.8
vestibulitis 7.5
orofacial pain 7.5
Cold intolerance 7.5
Motor dysfunction 7.2
Vulvodynia 7.1
localized edema 6.8
motor symptom 6.7
facial droop 6.6
loss of equilibrium 6.5
cancer pain 6.4
flushing 6.4
acute pain 6.3
dysesthesia 6.3
Severe pain 6.3
pain 6.1
hypalgesia 6.1
Flare 6.1
pachyonychia 6.1
impaired motor coordination 6.0
excessive sweating 6.0
Chronic pelvic pain 6.0
Postoperative pain 5.8
analgesia 5.7
blepharospasm 5.6
facial pain 5.6
body pain 5.5
myalgia 5.4
paresis 5.3
sciatica 5.3
tingling 5.3
paresthesia 5.2
numbness 5.1
bone pain 5.1
pelvic pain 5.1
loss of taste 5.0
mastalgia 5.0
incoordination 4.8
urinary frequency 4.4
abnormal gait 4.4
rhinorrhea 4.4
arthralgia 4.4
drooling 4.2
functional recovery 4.0
chronic back pain 4.0
skin damage 4.0
photophobia 4.0
neuralgia 3.8
otalgia 3.6
ENT 3.5
low back pain 3.5
erythema 3.4
dental pain 3.3
back pain 3.3
Wind 3.2
anesthesia 3.2
dystonia 3.1
knee pain 3.1
despair 2.9
epigastric pain 2.8
abdominal discomfort 2.8
discomfort 2.8
spasm 2.7
discomfort 2.7
neck pain 2.6
weakness 2.6
leg pain 2.6
fever of unknown origin 2.6
skin irritation 2.5
abdominal pain 2.5
acute stress 2.4
distraction 2.4
dysuria 2.3
pallor 2.3
shoulder pain 2.1
headache 2.1
hoarseness 2.1
acute abdomen 2.0
colic 1.9
tinnitus 1.9
insomnia 1.8
tremor 1.7
sleepiness 1.5
myoclonus 1.5
nausea 1.4
nausea and vomiting 1.4
dizziness 1.3
constipation 1.3
hypothermia 1.1
cough 1.0
agitation 1.0
spasticity 0.9
fatigue 0.9
vertigo 0.8
ataxia 0.6
Welt 0.6
vomiting 0.2
Ill 0.1
thinning 0.1
seizures -0.1
diarrhea -0.2
chest pain -0.5
respiratory distress -0.7
angina -0.8
dyspnea -1.2
collapse -1.2
Drug
Vedaprofen 10.8
Dizocilpine maleate 10.5
Ezlopitant 10.4
Elcatonin 9.8
Naropin 9.5
SNL 9.2
Nitecapone 9.1
Propentofylline 8.8
Camostat mesilate 8.8
Dipyrone 8.3
Gabapentin 8.2
Oxaliplatin 8.1
Duloxetine 8.1
Tramadol hydrochloride 8.0
Pregabalin 7.8
Parecoxib 7.8
Tapentadol 7.8
Perhexiline 7.7
Reboxetine 7.7
Flunixin 7.6
Pyridostigmine bromide 7.3
Pyridostigmine bromide 7.1
Cilnidipine 7.1
Domperidone 7.0
Ketorolac 7.0
Tramal 6.9
Clove 6.9
Marcaine 6.9
Compound 18 6.8
Ulinastatin 6.7
Proglumide 6.7
Celebrex 6.6
Tenoxicam 6.6
Vinpocetine 6.4
Monosodium glutamate 6.2
BOTOX 6.2
Bromelain 6.1
Salmon calcitonin 6.1
Ritanserin 6.1
TRM 6.0
Carbenoxolone 6.0
Bupivacaine 6.0
Botox 5.9
L-Ser 5.7
Magnesium sulfate 5.6
Vicryl 5.5
Donepezil 5.5
Nimesulide 5.4
Mirtazapine 5.3
CPZ 5.3
Sodium valproate 5.3
Teriparatide 5.2
Codeine 5.2
Xylocaine 5.2
Codeine 5.1
Modafinil 5.0
PMPA 5.0
DBS 4.8
IL-1ra 4.7
EHDP 4.6
Reserpine 4.6
TES 4.4
PPA 4.4
Metrizamide 4.4
Horizon 4.3
Vitamin B12 4.3
Cremophor EL 4.3
Kainic acid 4.2
-deoxyadenosine 4.1
Portal 4.1
Raloxifene 4.1
Amiloride 4.0
pyridoxal phosphate 3.9
Gelatin 3.8
Amiloride 3.8
Gastro 3.8
Photofrin 3.7
p75 3.7
nitroglycerin 3.6
Diphenhydramine 3.6
Galactose 3.6
Histamine 3.5
DMAP 3.4
Phentolamine 3.4
Clonidine 3.3
Fentanyl 3.3
Fraction 3.2
Nitric Oxide 3.2
ICI 3.2
Meth 3.2
Glycyrrhiza 3.1
Bayer 3.0
Ranitidine 2.9
Simvastatin 2.9
ENT 2.8
Docetaxel 2.8
Frontal 2.6
Indomethacin 2.5
Propofol 2.5
ACT 2.5
TAT 2.3
ETA 2.1
Taxol 1.9
HCH 1.8
Kenyan 1.8
caffeine 1.8
Fluorescein 1.7
niacin 1.7
PCB 1.5
lysine 1.4
Ethanol 1.3
vitamin E 1.1
Nephron 1.0
CSF 1.0
NADH 0.7
Biopolymers 0.5
ABC 0.5
CTX 0.3
Asn 0.1
Nephron 0.0
Gel -0.3
MAP -0.4
Dermatol -0.4
ROS -0.7
Leaf -0.8
IFN-gamma -1.2
IL-2 -1.3
Monit -1.5
Cardiovasc -4.0
Enzyme
PFL activase 12.3
lysine 2,3-aminomutase 10.5
NS protease 9.6
aminopeptidase Y 9.1
aminopeptidase I 7.7
pyruvate formate-lyase 7.6
acetoacetate decarboxylase 7.6
ethanolamine ammonia-lyase 7.3
cycloartenol synthase 7.3
GD3 synthase 7.0
galactose-1-phosphate uridylyltransferase 6.9
diol dehydratase 6.5
4-epimerase 6.4
IOR 6.4
triose-phosphate isomerase 6.0
uridyltransferase 5.9
aminopeptidase P 5.8
TSA 5.3
phosphoglycerate dehydrogenase 5.3
neutral sphingomyelinase 5.2
15-lipoxygenase 5.0
dihydropteridine reductase 4.9
CPN 4.8
hydrogenase 4.6
cathepsin S 4.6
PKG 4.6
hydrogenase 4.6
phosphoribulokinase 4.6
cystathionine gamma-lyase 4.5
SPT 4.5
CNPase 4.5
leucine aminopeptidase 4.5
isopeptidase 4.4
tissue kallikrein 4.3
CPS 4.3
GTP cyclohydrolase I 4.2
tryptophan synthase 4.2
PDH 4.2
fatty acid desaturase 4.1
CaMKII 3.9
SPC 3.8
SPT 3.8
tryptase 3.7
adenosine kinase 3.7
botulinum neurotoxin 3.7
PRE 3.7
chondroitinase 3.6
bromelain 3.6
heme oxygenase 3.5
glutamate decarboxylase 3.5
chondroitinase 3.5
GRK5 3.4
Thy1 3.3
TPP 3.3
rubisco 3.2
RNase P 3.2
guanylate cyclase 3.1
indoleamine 2,3-dioxygenase 3.1
phospholipase A2 3.1
TPP 3.1
NOS 3.1
aldose reductase 2.9
NO synthase 2.8
prostate-specific membrane antigen 2.8
tryptophan hydroxylase 2.8
chymotrypsin 2.7
arginase 2.7
adenylate kinase 2.6
caspase-1 2.5
lactase 2.5
phosphoglycerate kinase 2.5
mitogen-activated protein kinase 2.5
TAT 2.4
kinesin 2.3
MEK 2.2
peroxiredoxin 2.2
monoamine oxidase 2.2
MDP 2.2
sialidase 2.2
histone acetyltransferase 2.2
ribonucleotide reductase 2.1
ribonucleotide reductase 2.0
protein kinase 2.0
protein phosphatase 2A 2.0
kallikrein 2.0
elastase 2.0
hyaluronidase 2.0
peroxidase 2.0
glutathione peroxidase 2.0
protein kinase C 1.9
papain 1.9
pyruvate dehydrogenase 1.8
pyruvate dehydrogenase 1.8
superoxide dismutase 1.7
PDE 1.7
phospholipase C 1.7
neutrophil elastase 1.6
glyceraldehyde-3-phosphate dehydrogenase 1.5
glyceraldehyde-3-phosphate dehydrogenase 1.5
PARP 1.4
CPT 1.4
glyceraldehyde-3-phosphate dehydrogenase 1.4
ERK 1.4
MIP 1.3
tyrosine hydroxylase 1.3
glutamine synthetase 1.3
pyruvate kinase 1.2
pyruvate dehydrogenase 1.2
phosphatidylinositol 3-kinase 1.1
glyceraldehyde-3-phosphate dehydrogenase 1.1
DNA polymerase 1.1
dihydrofolate reductase 1.1
phosphoinositide 3-kinase 1.1
AST 1.0
collagenase 1.0
catalase 1.0
NQO1 1.0
AMPK 1.0
phosphodiesterase 1.0
AMPK 1.0
glyceraldehyde-3-phosphate dehydrogenase 0.9
aspartate aminotransferase 0.8
carbonic anhydrase 0.7
urease 0.7
caspase-9 0.7
reverse transcriptase 0.6
calcineurin 0.5
pepsin 0.5
lipoxygenase 0.5
cytochrome oxidase 0.5
ACE 0.4
topoisomerase 0.4
endonuclease 0.4
acetylcholinesterase 0.4
topoisomerase 0.3
NADPH oxidase 0.3
trypsin 0.2
urokinase-type plasminogen activator 0.2
thrombin 0.1
NADPH oxidase 0.1
caspase-3 0.0
cholinesterase -0.1
acid phosphatase -0.1
AMP-activated protein kinase -0.1
ATPase -0.1
alanine aminotransferase -0.1
neuraminidase -0.2
focal adhesion kinase -0.3
APC -0.4
RNase -0.4
RNA polymerase -0.5
renin -0.5
RNase -0.6
lipase -0.6
creatine kinase -0.6
adenylate cyclase -0.6
lysozyme -0.8
glutathione S-transferase -0.9
alkaline phosphatase -1.0
proteasome -1.2
more...
Compound
Ginsenoside Rf 12.0
Isosakuranetin 11.3
Spicamycin 11.3
1,2,3,4-tetrafluorobenzene 11.0
Budlein A 10.4
Budlein A 10.1
4-methylglutamic acid 9.6
4-methylglutamic acid 9.6
L-365260 9.3
1,5-isoquinolinediol 9.1
N-phenylpropanamide 9.1
1,4-difluorobenzene 9.0
Dezocine 8.8
4-methylquinazoline 8.7
Tricaine 8.3
Resiniferatoxin 8.2
9(10H)-anthracenone 8.2
T13 8.0
1-methyl-1H-indole 7.9
Hydrocodone 7.9
Myricitrin 7.9
Benzamil 7.7
Bergenin 7.7
Liquiritigenin 7.6
Hypotaurine 7.6
CH3NO2 7.5
Allyl isothiocyanate 7.5
Erythrosin 7.4
9(10H)-anthracenone 7.4
Vincristine 7.3
Alfentanil 7.3
isovaline 7.3
Glycolaldehyde 7.2
Cromolyn 7.2
MPE 7.2
Oxycodone 7.2
Tramadol 7.2
Ketorolac 7.1
DR-1 7.1
FMI 7.1
Carprofen 7.1
Tizanidine 7.0
pentanedioic acid 7.0
Vitexin 7.0
Carrageenan 7.0
Sumatriptan 6.9
Mexiletine 6.9
Muscarine 6.9
CH3NO2 6.9
hexopyranose 6.9
Fexofenadine 6.9
Dextromethorphan 6.9
DIMBOA 6.8
Glycopyrrolate 6.7
Mangiferin 6.7
Cuprizone 6.7
Paclitaxel 6.6
hexopyranose 6.6
hexopyranose 6.6
Fisetin 6.6
hexopyranose 6.6
NOP 6.5
Capsaicin 6.5
Morphine 6.5
Chlorpheniramine 6.5
Dimethyl fumarate 6.4
Chlorpheniramine 6.4
Sinomenine 6.4
Esculetin 6.4
IBP 6.3
IBP 6.3
Cannabidiol 6.3
UMP 6.2
Ethosuximide 6.2
CHM 6.2
Meloxicam 6.2
Fluvoxamine 6.2
carbamic acid 6.2
Bethanechol 6.1
Dynorphin 6.1
Sufentanil 6.1
Geraniol 6.1
Bupivacaine 6.0
fluorobenzene 6.0
acetone 6.0
Oxcarbazepine 6.0
TNB 6.0
T10 6.0
DAMGO 5.9
Agmatine 5.9
Riluzole 5.9
5-HTP 5.9
Puerarin 5.9
Naringenin 5.9
Carbamate 5.9
HMM 5.9
5-HTP 5.9
Naringenin 5.8
AEA 5.8
Chelerythrine 5.8
Chelerythrine 5.8
Crocin 5.7
NBQX 5.7
Minocycline 5.7
Matrine 5.7
Ropivacaine 5.7
Matrine 5.7
Matrine 5.7
UDP-galactose 5.6
PPADS 5.6
Tetrandrine 5.6
Tetrandrine 5.6
Tetrandrine 5.6
Tetrandrine 5.6
INN 5.6
IBA 5.6
Allopregnanolone 5.5
Mirtazapine 5.5
tetrahydrothiophene 5.5
SAN 5.5
Magnesium sulfate 5.5
Oxotremorine 5.5
Cystathionine 5.4
Allopregnanolone 5.4
Cystathionine 5.4
STZ 5.4
Evans Blue 5.4
IBA 5.4
Magnesium sulfate 5.4
Toluidine blue 5.4
Naringin 5.3
Loperamide 5.3
Memantine 5.3
Etanercept 5.3
01M 5.3
2,2,6,6-tetramethylpiperidine 5.2
Amitriptyline 5.2
Lidocaine 5.2
Betamethasone 5.2
1H-pyrazole 5.2
UDP-glucose 5.2
CPA 5.2
Codeine 5.1
Remifentanil 5.1
Thymoquinone 5.1
Ribose 5.1
ANI 5.1
R 2 5.1
CPZ 5.1
NMA 5.0
Ketamine 5.0
Gold, 5.0
Gold, 5.0
Gold, 5.0
Clomipramine 5.0
BzATP 4.9
Pioglitazone 4.9
THIP 4.9
1H-pyrazole 4.9
Piroxicam 4.9
more...