Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0162473 (Frey)
2,599 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 173
Mol 83
opioid receptor 78
TNF 74
cytokine 59
substance P 49
glial fibrillary acidic protein 44
NMDA receptor 43
tumor necrosis factor 42
axonal 39
bradykinin 38
calcitonin 35
TRPV1 34
GABA 32
IL-6 31
ATP 28
brain-derived neurotrophic factor 28
nerve growth factor 26
DRG 22
nitric oxide synthase 21
transient receptor potential vanilloid 1 20
nov 20
p38 19
inducible nitric oxide synthase 19
cyclooxygenase-2 18
CFA 18
COX-2 18
myeloperoxidase 18
hairy 17
ERK 17
interleukin-6 17
P2X 16
superoxide dismutase 16
lipopolysaccharide 16
Iba1 16
ANOVA 15
IL-10 15
calcium channel 15
extracellular signal-regulated kinase 15
dynorphin 14
ERK1 14
5-hydroxytryptamine 14
GSH 13
CD11b 13
CB1 13
insulin 13
TRPA1 12
HT3 12
CB2 12
gut 12
T13 12
T10 12
MAPK 12
Mot 11
Walker 11
NMR 11
STZ 11
glutamate receptor 11
chemokine 11
PBS 10
TLR4 10
CGRP 10
c-fos 10
OFQ 10
p65 10
cyclooxygenase 10
mast cell 10
5-HT1A 9
P2X3 9
SNS 9
MRI 9
SNL 9
cannabinoid receptor 9
5-HT3 receptor 9
collagen 9
oxytocin 9
NR2B 9
CO2 9
ionized calcium-binding adapter molecule 8
muscarinic receptor 8
LPS 8
She 8
cholecystokinin 8
catalase 8
NGF 7
endothelin-1 7
neurotrophin 7
interleukin-10 7
glutathione peroxidase 7
neuropeptide Y 7
WIN 7
PKC 7
phospholipase A2 7
TNF-alpha 7
ankyrin 1 7
CCL2 7
B12 7
cage 7
sodium channel 7
heme oxygenase-1 6
member 1 6
GABA(A) receptor 6
caspase-3 6
olfactory 6
COX-1 6
metabotropic glutamate receptor 6
mouse) 6
caveolin-3 6
5-HT receptor 6
adenosine receptor 6
endoplasmic reticulum 6
adenosine A1 receptor 6
somatostatin 6
rat) 6
Cytokine 6
monocyte chemoattractant protein-1 6
PGP 9.5 6
chymotrypsin 6
mGluR5 5
AKT 5
CA1 5
MIA 5
MEK 5
NR1 5
CSF 5
ionotropic 5
PKG 5
ATPase 5
GAD65 5
glucocorticoid receptor 5
interferon 5
BRL 5
neurotrophic factor 5
polypeptide 5
guanylate cyclase 5
JNK 5
proteoglycan 5
ENT 5
corticotropin-releasing factor 5
CX3CR1 5
orexin 5
Nav1.7 5
5-HT7 5
CD1 5
SAP 5
Calcitonin 5
ASIC3 5
IL-1 5
ARC 5
PKA 5
CREB 5
short form 5
fatty acid amide hydrolase 5
hole 4
IL-4 4
amylase 4
MCP-1 4
Pol 4
HO-1 4
NOS2 4
more...
Disease
Frey 2599
cold 253
chronic pain 192
neuropathy 126
cancer 112
peripheral neuropathy 100
tumor 76
chronic pancreatitis 72
diabetes 72
depression 66
diabetic neuropathy 48
osteoarthritis 36
adenoma 29
facial palsy 28
migraine 25
carcinoma 24
arthritis 24
mononeuropathy 21
fibromyalgia 21
Mycoplasma 20
stroke 20
hyperglycemia 19
pancreatitis 19
ischemia 18
trigeminal neuralgia 16
nerve lesion 16
bone cancer 15
Evans 15
NAME 14
colitis 13
GSH 13
Parkinson's disease 13
pruritus 13
interstitial cystitis 12
Gustatory sweating 12
cystitis 12
hypertension 11
colorectal cancer 9
adenocarcinoma 9
herpes zoster 8
postherpetic neuralgia 8
regional pain syndrome 8
rubella 8
sensory neuropathy 8
neuroma 8
food allergy 7
polyneuropathy 7
rheumatoid arthritis 7
Diabetic neuropathy 7
cognitive impairment 7
multiple sclerosis 7
cornea 6
tumor growth 6
causalgia 6
sialadenitis 6
Warthin's tumor 6
squamous cell carcinoma 6
ash 6
monoarthritis 6
dysphagia 6
HIV 6
pancreatic cancer 5
breast cancer 5
Bladder 5
addiction 5
Nose 5
SEM 5
Bladder 5
encephalomyelitis 5
Bladder 5
anxiety disorders 5
acute pancreatitis 5
Blocking 5
cholestasis 5
Syndrome 5
obesity 5
benign tumor 5
radiculopathy 5
cerebral ischemia 5
parotitis 5
catalepsy 5
fibrosarcoma 4
sialolithiasis 4
herniated disc 4
disinhibition 4
irritable bowel syndrome 4
amyotrophic lateral sclerosis 4
gallstones 4
West 4
synovitis 4
type 2 diabetes 4
Pleomorphic adenoma 4
osteoporosis 4
prostatitis 4
Brown 4
BPS 4
melanoma 4
hypoglycemia 4
Ludwig 4
carpal tunnel syndrome 4
malnutrition 4
dysphonia 4
Colitis 3
neuroblastoma 3
fits 3
Pancreas 3
Pancreas 3
neurological disease 3
bruxism 3
inguinal hernia 3
infectious diseases 3
memory impairment 3
degenerative disc disease 3
metastases 3
myelopathy 3
motor neuron disease 3
Complex regional pain syndrome 3
sickle cell disease 3
cholangitis 3
Still 3
biliary obstruction 3
stuttering 3
varicella 3
type 1 diabetes 3
osteosarcoma 3
atopic dermatitis 3
ADHD 3
Facial palsy 3
MPE 3
posttraumatic stress disorder 3
EDA 3
uterus 3
alcoholic neuropathy 3
mole 2
Horner's syndrome 2
peritonitis 2
encephalopathy 2
Chronic sialadenitis 2
Edwards 2
major depressive disorder 2
neuritis 2
schwannoma 2
rhinitis 2
social stress 2
Li-Fraumeni syndrome 2
pheochromocytoma 2
Ross syndrome 2
compartment syndrome 2
Generalized hyperhidrosis 2
progressive supranuclear palsy 2
acute arthritis 2
galactosemia 2
ulcerative colitis 2
autoimmune disease 2
herpes simplex 2
psychological stress 2
suicide 2
Nelson 2
TMD 2
Hereditary angioedema 2
more...
Symptom
pain 1508
analgesia 123
anesthesia 84
Neuropathic pain 78
flushing 43
acute pain 26
myalgia 23
cancer pain 21
headache 19
weakness 19
paresis 19
functional recovery 18
numbness 15
paresthesia 15
orofacial pain 14
abdominal pain 14
discomfort 13
discomfort 13
bladder pain 12
arthralgia 12
pelvic pain 11
erythema 11
back pain 10
hyperesthesia 10
facial pain 9
bone pain 9
low back pain 9
fatigue 8
dystonia 6
Visceral pain 6
dysesthesia 6
seizures 6
nausea 5
Postoperative pain 5
sciatica 5
tremor 5
Inflammatory pain 5
ENT 5
Central post-stroke pain 4
distraction 4
diarrhea 4
incoordination 4
rhinorrhea 4
spasm 4
motor symptom 4
Peripheral neuropathic pain 4
tingling 4
cough 4
blepharospasm 4
Mechanical pain 3
sleepiness 3
excessive sweating 3
insomnia 3
hypothermia 3
vomiting 3
Radicular pain 3
agitation 2
Welt 2
Grimace 2
photophobia 2
constipation 2
dizziness 2
vestibulitis 2
acute stress 2
skin pain 2
abnormal gait 2
Wind 2
tinnitus 2
Chronic pelvic pain syndrome 2
nerve pain 2
ataxia 2
nausea and vomiting 2
knee pain 2
urinary frequency 2
neck pain 2
neuralgia 2
skin damage 2
epigastric pain 2
mastalgia 1
hypalgesia 1
Lower abdominal pain 1
Throbbing pain 1
chest pain 1
Vulvodynia 1
shoulder pain 1
Cold intolerance 1
Pancreatic pain 1
sialectasis 1
UTI symptoms 1
chronic back pain 1
thinning 1
drooling 1
acute abdomen 1
Intractable pain 1
despair 1
dyspnea 1
Central pain syndrome 1
dysuria 1
otalgia 1
Ill 1
localized edema 1
loss of taste 1
facial droop 1
spasticity 1
body pain 1
pallor 1
angina 1
fever of unknown origin 1
Chronic pelvic pain 1
respiratory distress 1
Abnormal sensation 1
dental pain 1
Cutaneous hyperalgesia 1
collapse 1
pachyonychia 1
Motor dysfunction 1
Incisional pain 1
hoarseness 1
loss of equilibrium 1
vertigo 1
Flare 1
impaired motor coordination 1
Burning pain 1
abdominal discomfort 1
leg pain 1
colic 1
skin irritation 1
Radiating pain 1
myoclonus 1
Central pain 1
Severe pain 1
Other pain 1
Drug
Gabapentin 22
Oxaliplatin 21
Dermatol 16
lysine 13
nitroglycerin 9
SNL 9
Pregabalin 8
Domperidone 7
Duloxetine 7
Portal 6
caffeine 6
ENT 5
Histamine 5
CSF 5
ICI 4
Bupivacaine 4
p75 4
Propentofylline 3
NADH 3
vitamin E 3
Dipyrone 3
Nephron 3
pyridoxal phosphate 3
Ketorolac 3
Indomethacin 3
IL-1ra 3
-deoxyadenosine 3
Tapentadol 2
Ethanol 2
Vicryl 2
Dizocilpine maleate 2
Reboxetine 2
Clonidine 2
Horizon 2
Nitric Oxide 2
Gelatin 2
Elcatonin 2
Vitamin B12 2
Amiloride 2
Botox 2
PMPA 2
Amiloride 2
Donepezil 2
DBS 2
Reserpine 2
Fraction 2
TRM 2
niacin 1
Metrizamide 1
Proglumide 1
Camostat mesilate 1
Pyridostigmine bromide 1
Nitecapone 1
Carbenoxolone 1
EHDP 1
Frontal 1
Codeine 1
DMAP 1
Parecoxib 1
Bayer 1
Xylocaine 1
Fluorescein 1
Propofol 1
ETA 1
Leaf 1
Vinpocetine 1
Pyridostigmine bromide 1
Tenoxicam 1
Cardiovasc 1
L-Ser 1
Bromelain 1
Biopolymers 1
Monit 1
Photofrin 1
Monosodium glutamate 1
Gastro 1
Mirtazapine 1
Cilnidipine 1
Gel 1
CPZ 1
BOTOX 1
IFN-gamma 1
Kenyan 1
Ezlopitant 1
Salmon calcitonin 1
Modafinil 1
Ritanserin 1
Nimesulide 1
Phentolamine 1
Tramal 1
Simvastatin 1
Perhexiline 1
Teriparatide 1
Vedaprofen 1
Magnesium sulfate 1
Ulinastatin 1
Flunixin 1
Codeine 1
PCB 1
ACT 1
CTX 1
TES 1
Ranitidine 1
Marcaine 1
Fentanyl 1
MAP 1
Cremophor EL 1
Raloxifene 1
Asn 1
Meth 1
TAT 1
Glycyrrhiza 1
Diphenhydramine 1
Galactose 1
Taxol 1
ABC 1
Sodium valproate 1
HCH 1
ROS 1
Kainic acid 1
Celebrex 1
Nephron 1
Naropin 1
IL-2 1
Compound 18 1
Docetaxel 1
PPA 1
Tramadol hydrochloride 1
Clove 1
Enzyme
mitogen-activated protein kinase 43
protein kinase 27
peroxidase 21
ERK 20
superoxide dismutase 16
protein kinase C 15
phospholipase A2 10
NO synthase 9
catalase 9
MEK 7
glutathione peroxidase 7
hydrogenase 7
hydrogenase 7
lysine 2,3-aminomutase 6
guanylate cyclase 6
chymotrypsin 6
ATPase 5
PKG 5
phospholipase C 5
NOS 5
CaMKII 5
heme oxygenase 4
TSA 4
reverse transcriptase 4
trypsin 4
monoamine oxidase 4
caspase-3 3
elastase 3
caspase-1 3
pyruvate formate-lyase 3
focal adhesion kinase 3
phosphodiesterase 3
PARP 3
15-lipoxygenase 3
tryptase 3
SPC 3
4-epimerase 3
collagenase 3
DNA polymerase 3
thrombin 3
aspartate aminotransferase 3
tyrosine hydroxylase 3
acetylcholinesterase 3
leucine aminopeptidase 3
GD3 synthase 2
calcineurin 2
CPS 2
PRE 2
RNA polymerase 2
PFL activase 2
AMPK 2
aldose reductase 2
botulinum neurotoxin 2
hyaluronidase 2
endonuclease 2
neutral sphingomyelinase 2
ACS 2
arginase 2
glutamate decarboxylase 2
aminopeptidase I 2
phosphatidylinositol 3-kinase 2
alkaline phosphatase 2
chondroitinase 2
renin 2
chondroitinase 2
kinesin 2
papain 2
kallikrein 2
alanine aminotransferase 2
ACE 2
tissue kallikrein 2
GTP cyclohydrolase I 1
neutrophil elastase 1
aminopeptidase Y 1
cholinesterase 1
proteasome 1
neuraminidase 1
MIP 1
glyceraldehyde-3-phosphate dehydrogenase 1
SPT 1
glyceraldehyde-3-phosphate dehydrogenase 1
phosphoribulokinase 1
lipoxygenase 1
urease 1
dihydrofolate reductase 1
glyceraldehyde-3-phosphate dehydrogenase 1
aminopeptidase P 1
protein phosphatase 2A 1
glutathione S-transferase 1
dihydropteridine reductase 1
MDP 1
lactase 1
CPT 1
histone acetyltransferase 1
caspase-9 1
cytochrome oxidase 1
isopeptidase 1
bromelain 1
pyruvate kinase 1
cystathionine gamma-lyase 1
TAT 1
prostate-specific membrane antigen 1
diol dehydratase 1
AST 1
creatine kinase 1
indoleamine 2,3-dioxygenase 1
RNase P 1
APC 1
lipase 1
CPN 1
topoisomerase 1
urokinase-type plasminogen activator 1
tryptophan hydroxylase 1
NADPH oxidase 1
topoisomerase 1
glutamine synthetase 1
PDE 1
pyruvate dehydrogenase 1
RNase 1
NS protease 1
PDH 1
phosphoinositide 3-kinase 1
pyruvate dehydrogenase 1
lysozyme 1
GRK5 1
CNPase 1
adenylate cyclase 1
NADPH oxidase 1
RNase 1
glyceraldehyde-3-phosphate dehydrogenase 1
phosphoglycerate dehydrogenase 1
adenylate kinase 1
ribonucleotide reductase 1
IOR 1
fatty acid desaturase 1
sialidase 1
adenosine kinase 1
ribonucleotide reductase 1
galactose-1-phosphate uridylyltransferase 1
NQO1 1
cycloartenol synthase 1
pepsin 1
uridyltransferase 1
glyceraldehyde-3-phosphate dehydrogenase 1
pyruvate dehydrogenase 1
peroxiredoxin 1
AMPK 1
tryptophan synthase 1
acid phosphatase 1
cathepsin S 1
triose-phosphate isomerase 1
carbonic anhydrase 1
rubisco 1
phosphoglycerate kinase 1
ethanolamine ammonia-lyase 1
acetoacetate decarboxylase 1
TPP 1
SPT 1
Thy1 1
AMP-activated protein kinase 1
more...
Compound
Dec 191
acetone 112
TNF 74
water 70
calcium 63
glutamate 60
5-HT 49
nitric oxide 48
sodium 47
Clin 45
iodine 39
Morphine 38
oxygen 38
arginine 36
glucose 35
GABA 33
GABA 33
NMDA 30
hydrogen 29
DNA 28
ATP 28
noradrenaline 25
Paclitaxel 23
acetic acid 23
Capsaicin 20
phosphate 20
His 19
sulfate 16
Gly 16
serine 16
lysine 16
tyrosine 15
CO2 15
iron 14
GSH 13
GSH 13
STZ 13
Vincristine 12
ethanol 12
T13 12
T10 12
cGMP 12
cysteine 11
cAMP 11
galactose 11
alanine 11
potassium 10
gamma-aminobutyric acid 10
salt 10
Neuronal 10
AMPA 10
DMSO 9
Asp 9
acetate 9
PGE 9
leucine 9
PGE2 8
Tramadol 8
tryptophan 8
UDP-glucose 8
NH2 8
Substance P 8
Salt 7
threonine 7
HCl 7
DAMGO 7
A 1 7
UDP 7
Glutamate 7
UMP 7
Lidocaine 7
nickel 6
AEA 6
urea 6
Carrageenan 6
CPA 6
Phe 6
UDP-galactose 6
Ketamine 6
phosphorus 6
caffeine 6
nitrogen 6
adenosylmethionine 6
DDP 6
MIA 5
Naloxone 5
glycerol 5
Calcitonin 5
aluminum 5
BRL 5
Histamine 5
Bradykinin 5
MEK 5
APAP 5
uridine 5
titanium 4
NBQX 4
tryptophan 4
tryptophan 4
tryptophan 4
aspartic acid 4
Sumatriptan 4
UTP 4
H2S 4
aspartic acid 4
formaldehyde 4
Curcumin 4
pyrazine 4
5-HTP 4
HMM 4
Allyl isothiocyanate 4
manganese 4
5-HTP 4
Bupivacaine 4
Minocycline 4
T11 4
nicotinamide 4
ICI 4
piperazine 4
Adenosine 4
bromide 4
GMP 4
NAD 4
5-hydroxytryptophan 4
Diazepam 4
pyridine 4
hydroxyindoleacetic acid 3
silver 3
MPE 3
EDTA 3
Dextromethorphan 3
Baclofen 3
EDTA 3
2,2,6,6-tetramethylpiperidine 3
aspartic acid 3
Alfentanil 3
1H-pyrazole 3
Norepinephrine 3
Neo 3
Oxycodone 3
Evans Blue 3
MK801 3
Cannabidiol 3
L-DOPA 3
Acetone 3
4-nitrophenyl 3
1H-indole 3
carbamic acid 3
Mexiletine 3
ammonium 3
IBA 3
nitrate 3
IBA 3
D-Ala 3
dUTP 3
1H-pyrazole 3
Ketorolac 3
NOP 3
Dynorphin 3
Hematoxylin 3
more...