Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0162316 (iron deficiency anemia)
 3,806 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Complete blood counts and levels of ferritin in serum (S-Fer) in 62 college students were analyzed continuously to clarify the effects of blood donation. In 14 (45%) of 31 females, hemoglobin (Hb) and S-Fer levels showed decrease of more than 5% and 30%, respectively, four weeks after donation of 200ml or 400ml of blood. In 11 (35%) of the males and 6% of the females, Hb levels increased over 5% during the same period. In 61% of the males and 45% of the females, S-Fer levels decreased. In only 19% of the males, the Hb and S-Fer levels were unchanged. Red blood cell (RBC) counts and Hb levels showed almost the same pattern. In 39% of the males and 48% of the females, the white blood cell (WBC) counts decreased more than 10%. In 10% of the males and 23% of the females, WBC counts increased more than 10% after blood donation. The WBC and RBC counts did not always show the same pattern of variation. After blood donation, the incidence of iron deficiency anemia among females increased from 13% to 23% and the incidence of latent iron deficiency among females increased from 10% to 42%.
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PMID:[The states of recovery of blood counts and serum ferritin levels after blood donation]. 828 4

An iron supplement was given to female blood donors to prevent iron deficiency after blood donation. The levels of items related to red blood cells and serum ferritin (S-Fer) among 17 iron-takers and 31 non-iron-takers were analyzed continuously. In most of the non-iron-takers, the S-Fer levels did not recover within four weeks after the donation of 200ml or 400ml of blood. In the approximately half of the donors, hemoglobin (Hb) levels did not recover either. However, in 59% of those taking iron supplements three times the amount of iron lost by donation, the levels of Hb and S-Fer recovered within two weeks. In the remaining 41%, the Hb levels recovered within four weeks by taking the iron supplement. Four weeks after blood donation, the incidence of iron deficiency anemia among the non-iron-takers increased from 13% to 23% and the incidence of latent iron deficiency among the non-iron-takers increased from 32% to 42%. However, the incidence of iron deficiency anemia among the iron-takers remained 0% and the incidence of latent iron deficiency among the iron-takers decreased from 12% to 6%.
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PMID:[Recovered state of iron in female blood donors--after taking an iron supplement]. 855 82

Laboratory tests used in the diagnosis of iron status lack specificity in defining iron deficiency anaemia (IDA) and anaemia of inflammation (AI). The serum transferrin receptor (sTfR) may provide more information in this regard. The iron status of 561 pre-school children was determined and classified using the conventional measurements. The value of the concentration of sTfR, the ratio of sTfR (microg/ml) to LogSF (microg/l) (TfR-Index), and the Log of the ratio of sTfR (microg/l) to SF (microg/l)--(LogTfR:Fer ratio), in the classification of the iron status were determined by comparing their distributions across the classification of iron status. Although there were significant differences in sTfR and TfR-Index across the categories of iron status, there was considerable overlap. All subjects with iron deficiency had LogTfR:Fer ratio > 2.55, whereas in all subjects classified as AI it was < 2.55, thus clearly separating the two. The LogTfR:Fer ratio was not able to exclude IDA in the presence of inflammation. However, in cases of combined IDA and AI the LogTfR:Fer ratio was < 2.55 but increased to > 2.55 after resolution of the inflammation. This novel method of calculating the LogTfR:Fer ratio may provide a more precise classification of the iron status of children.
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PMID:The ratio of serum transferrin receptor and serum ferritin in the diagnosis of iron status. 1172 16