Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0162316 (iron deficiency anemia)
 3,806 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The oral mucosal changes in iron deficiency anemia were studied in a selected hospital population. A high incidence of oral lesions was present in the anemic group as compared to age- and sex-matched controls. Atrophic changes of the tongue were quite characteristic clinically, and a significant reduction in the mean epithelial thickness of the buccal mucosa was determined histologically.
 ...
PMID:Oral mucosal changes in iron deficiency anemia in a Sri Lankan female population. 657 46

The common characteristics of primary atrophic rhinitis were studied in 46 Thai patients. From history and demographic data the female to male ratio was found to be 5.6 to 1. The significance of environmental factors was supported by the findings that 69.6% were people from rural areas and 43.5% were industrial workers but a hereditary factor has not been confirmed. The results of the blood tests did not elucidate iron deficiency anemia or nutritional deficiency as the cause of primary atrophic rhinitis. However, all nasal swab cultures yielded pathogenic organisms where Klebsiella species especially, K. ozaena, were the most common bacteria isolated which were 100% susceptible to cephalosporins. This finding together with the evidence of sinusitis seen in 58.7% of either plain x-rays or CT scans, was suggestive of the important role of infection in atrophic rhinitis. Atrophic change of the mucosa and bone with widening of the nasal cavity were constant findings in the CT scans but the developmental anomaly of the maxillary antrum was found in only 15.2%. The histological study showed characteristic changes especially squamous metaplasia and 80% of the cases were compatible with the Type II histopathological classification, i.e. vasodilatation of the capillaries. The mucociliary function was proven to be impaired in accordance with the loss of cilia. The evidence of Type I allergy demonstrated by skin testing, which was obvious in 85%, is highly suggestive of allergic/immunologic disorders. Although many factors have been cited previously as the possible cause of primary atrophic rhinitis, the common characteristics found in our patients indicate that only bacterial infection, environmental factors and allergic/immunologic disorders could be one or more of its multifactorial etiology and should be further investigated.
 ...
PMID:Characteristics of atrophic rhinitis in Thai patients at the Siriraj Hospital. 1056 92

Atrophic chronic gastritis and Helicobacter pylori infection are considered possible causes of iron deficiency anemia, and sideropenic anemia is also frequent after subtotal gastrectomy. In this study, thirty-three patients who underwent subtotal gastrectomy for primary adenocarcinoma of stomach were follow-up for at least 3 years, and included in this analysis. The presence of atrophic gastritis and H. pylori infection were detected by biopsy sampling and endoscopy every year after surgery. The iron status was evaluated by the assay of serum ferritin, serum iron and hemoglobin level. Statistical analysis revealed that atrophic gastritis was associated with lower iron serum levels, and gastric stump H. pylori infection was related to lower serum ferritin levels; on the contrary, no correlation of these factors with sex, age, malabsorption symptoms and stage of tumor was found. Atrophic chronic gastritis and Helicobacter pylori infection seem to play an important role as possible causes of post gastrectomy anaemia.
 ...
PMID:[Correlation between chronic gastritis of the gastric stump, Helicobacter pylori infections and iron deficiency after gastrectomy for gastric cancer]. 1242 77