Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0162275 (ketonuria)
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Human Gene/Protein
Succinyl-CoA:3-ketoacid CoA transferase 13.0
mitochondrial acetoacetyl-CoA thiolase 11.3
WDR72 11.2
HLA-B61 11.0
Fructose 1,6-bisphosphatase 10.9
PCCB 10.5
SLC5A2 10.4
isovaleryl-CoA dehydrogenase 10.3
FBP2 10.3
MMAA 10.2
SCOT 10.2
GLUD1 10.1
SSADH 10.0
CUBN 9.9
cblA 9.4
Sorbitol dehydrogenase 9.3
MADD 9.3
MODY2 9.2
Holocarboxylase synthetase 9.2
HLA-antigen 9.2
HLA-B18 9.0
nucleotide binding protein 9.0
sodium-dependent glucose transporter 8.9
LRP2 8.9
HNF1alpha 8.8
WSS 8.7
malonyl-CoA decarboxylase 8.6
propionyl-CoA carboxylase 8.6
toll-like receptor 3 8.5
FBP1 8.4
OCA-B 8.3
biotinidase 8.2
HLA Class II 8.1
LCT 8.1
RT6 8.1
COL4A3 8.1
SGLT2 8.0
jerky 7.9
GPD 7.9
ASAT 7.9
lactic acid dehydrogenase 7.9
3-ketoacyl-CoA thiolase 7.7
cubilin 7.7
Glutamic acid decarboxylase 7.7
Human leukocyte antigen 7.7
MODY 7.7
IDDM 7.7
calcium sensing receptor 7.6
HNF1B 7.6
nephropathic cystinosis 7.6
GCK 7.5
glycerol kinase 7.5
oxoglutarate 7.5
Pyruvate carboxylase 7.4
BTS 7.4
medium-chain acyl-CoA dehydrogenase 7.3
ABG 7.3
DIS 7.3
DR8 7.2
HNF1 7.1
obestatin 7.0
glycine decarboxylase 6.9
glutamic acid decarboxylase 6.9
HML 6.8
MCT 6.8
HLA-DR4 6.7
NIDDM 6.7
FBS 6.6
APO 6.6
MEN1 6.6
GAD 6.6
MELAS 6.5
GAD65 6.4
SCS 6.3
transcobalamin II 6.3
DR3 6.3
L-asparaginase 6.3
glucagon 6.2
IA-2 6.2
GPT 6.2
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Disease
Glycerol intolerance 15.8
Postparturient hemoglobinuria 14.8
Ketotic hypoglycemia 14.2
Ketonemia 13.9
Steroid-induced diabetes 13.2
Starvation ketoacidosis 13.2
Glycogen storage disease type 0 13.2
acetonemia 13.1
myocardosis 13.0
Malonyl-CoA decarboxylase deficiency 12.8
Armanni-Ebstein lesion 12.8
Neonatal diabetes mellitus 11.9
caffeine abuse 11.8
Succinic semialdehyde dehydrogenase deficiency 11.6
Febrile illness 11.5
fructose-1,6-diphosphatase deficiency 11.4
Fasting hypoglycemia 11.1
ketosis 10.9
diabetic coma 10.9
alcoholic ketoacidosis 10.8
Insulin autoimmune syndrome 10.8
diabetic ketoacidosis 10.6
Late pregnancy 10.3
Altered mental status 10.1
Rabson-Mendenhall syndrome 10.0
propionic acidemia 9.9
hyperglycinemia 9.7
Reye 9.4
Nesidioblastosis 9.4
hyperchloremia 9.3
MODY2 9.3
hemichorea 9.2
Biotinidase deficiency 9.1
Psoas abscess 9.1
brittle diabetes 9.0
methylmalonic acidemia 9.0
Reye's syndrome 8.8
MODY3 8.7
Epidermolysis bullosa acquisita 8.7
diabetic angiopathy 8.6
Lymphocytic infiltration 8.6
postmaturity 8.6
MCAD deficiency 8.6
WSS 8.5
PC deficiency 8.5
hereditary fructose intolerance 8.2
aminoaciduria 8.1
NPH 8.1
metritis 8.0
ASAT 8.0
hyperglycemia 8.0
gastrointestinal dysfunction 8.0
diabetic hyperglycemia 8.0
lipidosis 7.8
Traumatic Stress Disorder 7.8
drug-induced hepatitis 7.8
diffuse goiter 7.8
Wernicke's encephalopathy 7.8
hypoglycemia 7.8
renal papillary necrosis 7.7
Mallory-Weiss syndrome 7.7
beriberi 7.6
hyperosmolality 7.6
Ullrich 7.5
maple syrup urine disease 7.5
acanthosis nigricans 7.5
Fanconi syndrome 7.4
generalized lipodystrophy 7.4
trophoblastic tumor 7.4
glutaric aciduria 7.4
delirium tremens 7.3
sideroblastic anemia 7.2
renal tubular acidosis 7.2
MODY 7.1
glycogen storage disease 7.0
azotemia 7.0
FBS 7.0
type 1 diabetes 7.0
alkalosis 7.0
MELAS 6.9
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Symptom
ketonuria 15.8
excessive urination 11.8
Diarrhea and vomiting 11.2
hyperemesis gravidarum 11.0
Hemiballism 10.2
polyuria 9.3
sighing 9.2
polydipsia 9.1
hyperemesis 8.6
inanition 8.0
lethargy 7.9
lassitude 7.7
meningism 7.4
right upper quadrant pain 7.4
tachypnea 7.1
nausea and vomiting 7.0
chorea 6.8
emaciation 6.8
retching 6.7
hypoproteinemia 6.7
hepatomegaly 6.5
forgetfulness 6.4
vomiting 6.3
renal colic 6.2
enuresis 6.1
hypotonia 5.9
acute abdominal pain 5.9
catatonia 5.7
abnormal gait 5.7
hunger 5.7
starvation 5.7
anorexia 5.5
pallor 5.5
asthenia 5.4
abdominal pain 5.1
nausea 5.0
blurred vision 4.8
sleepiness 4.8
Ill 4.7
rhinorrhea 4.7
agitation 4.3
exhaustion 4.1
epigastric pain 4.1
dysarthria 3.9
weakness 3.9
myoclonus 3.8
acute stress 3.6
dizziness 3.6
constipation 3.5
fatigue 3.5
ataxia 3.4
seizures 3.4
hypothermia 3.3
myalgia 3.1
overweight 3.1
tinnitus 3.1
dyspnea 3.0
acidity 2.9
hypercapnia 2.9
dystonia 2.8
syncope 2.6
distraction 2.6
respiratory distress 2.6
splenomegaly 2.5
insomnia 2.4
cough 2.3
back pain 2.2
diarrhea 2.0
tremor 1.6
discomfort 1.4
discomfort 1.2
headache 1.0
anesthesia 0.6
pain 0.6
Drug
Calcium hopantenate 12.8
Rompun 10.0
Insulin glargine 9.2
Dilantin 8.5
Salicylate 8.3
Sandostatin 7.6
Sandostatin 7.6
Mirtazapine 7.5
Iohexol 6.8
Fructose 6.5
Glucagon 5.9
Serum albumin 5.5
Phenytoin 5.4
Growth hormone 5.3
Growth hormone 5.2
Bayer 5.2
Diurnal 5.1
Fluorescein 4.9
Kenyan 4.0
citric acid 3.5
lactose 1.8
ampicillin 1.8
caffeine 1.4
NADH 1.4
ascorbate 1.3
lysine -0.0
Cardiovasc -1.8
Dermatol -2.2
Enzyme
isovaleryl-CoA dehydrogenase 10.3
malonyl-CoA decarboxylase 8.6
propionyl-CoA carboxylase 8.4
propionyl-CoA carboxylase 8.4
biotinidase 8.2
phosphomannose isomerase 7.3
glycerol kinase 7.3
lactic acid dehydrogenase 7.0
lactic acid dehydrogenase 6.9
acyl-CoA dehydrogenase 6.3
lactic acid dehydrogenase 6.2
glycerol-3-phosphate dehydrogenase 6.0
glycerol-3-phosphate dehydrogenase 6.0
SCS 5.8
sorbitol dehydrogenase 5.8
asparaginase 5.4
lipoprotein lipase 5.4
transpeptidase 5.3
pyruvate carboxylase 5.2
thyroid peroxidase 5.2
leucine aminopeptidase 5.1
ornithine transcarbamylase 5.1
AST 4.8
hormone-sensitive lipase 4.7
glutamate decarboxylase 4.7
ADH 4.7
pyruvate dehydrogenase 4.4
diaphorase 4.4
glucokinase 4.3
diaphorase 4.3
glucose-6-phosphatase 4.2
aldose reductase 4.1
aldolase 4.1
pyruvate dehydrogenase 4.1
pyruvate dehydrogenase 4.0
NADPH-diaphorase 3.9
succinate dehydrogenase 3.8
aspartate aminotransferase 3.7
alcohol dehydrogenase 3.6
lipase 3.6
CPR 3.5
glucose oxidase 3.4
NQO1 3.2
lactate dehydrogenase 3.0
glucose-6-phosphate dehydrogenase 2.9
xanthine oxidase 2.8
cytochrome oxidase 2.7
complex I 2.7
alanine aminotransferase 2.7
gamma-glutamyl transpeptidase 2.7
ACE 2.7
cholinesterase 2.2
acid phosphatase 2.2
NO synthase 1.9
renin 1.7
creatine kinase 1.6
adenylate cyclase 1.6
alkaline phosphatase 1.3
acetylcholinesterase 1.0
caspase-3 0.7
catalase 0.1
superoxide dismutase -0.0
Compound
Phenistix 13.8
5-hydroxyhexanoic acid 11.8
Methylcitric acid 11.4
3-methyl-2-oxopentanoate 10.4
OHB 9.7
Succinyl-CoA 9.5
1,3-butanediol 9.4
1,3-butanediol 9.3
Chlorpropamide 9.2
3-hydroxybutyric acid 9.0
3-hydroxy-2-butanone 8.8
Ritodrine 8.7
Sorbinil 8.7
3-hydroxyisovaleric acid 8.4
Sarin 8.2
3-hydroxy-2-butanone 7.9
sebacic acid 7.9
sebacic acid 7.9
Mirtazapine 7.8
sebacic acid 7.8
Phlorizin 7.5
Acarbose 7.3
PTU 7.2
VLA 7.1
Acetone 6.9
Xylose 6.9
alloxan 6.8
Eosin 6.8
adipate 6.8
Inosine 6.7
Carnitine 6.7
alpha-Tocopherol 6.6
Eosin 6.6
PTU 6.6
Fructose 6.4
HMF 6.4
Dichloroacetate 6.4
1,4-butanediol 6.3
DOPE 6.2
Sorbitol 6.2
3-methylhistidine 6.2
2,3-butanediol 6.2
2,3-butanediol 6.2
2,3-butanediol 6.2
DPC 6.2
GPT 6.2
malonic acid 6.1
Enalapril 6.0
Olanzapine 6.0
Glucagon 5.9
hydroxyglutarate 5.9
FDP 5.9
FFA 5.8
A 71 5.7
butyric acid 5.6
Oil Red O 5.6
glucose 5.5
butyric acid 5.5
acetone 5.5
STZ 5.5
Insulin 5.5
butyric acid 5.4
Uric acid 5.3
HMG-CoA 5.3
Oil Red O 5.3
Guo 5.2
dicarboxylic acid 5.2
isopropanol 5.2
Biotin 5.1
folinic acid 5.1
propylene glycol 5.0
ANCA 4.9
1-propanol 4.9
Pyruvate 4.9
L-carnitine 4.9
SPM 4.9
propylene glycol 4.8
GAP 4.8
Haloperidol 4.8
CoA 4.7
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