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Query: UMLS:C0162275 (ketonuria)
 553 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although metabolic disorders are a frequent concern in cattle, they are not commonly recognized in bulls. The combination of hyperglycemia, acetonemia, ketonuria, and glycosuria in a bull was highly suggestive of diabetes mellitus. This uncommon diagnosis was confirmed by results of intravenous glucose tolerance testing. Results of the test and serum insulin values were further able to classify the disease in this bull as type-I diabetes mellitus.
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PMID:Type-I diabetes mellitus in a bull. 221 31

A subtoxic dose of isopropyl alcohol was ingested by three subjects to evaluate the time to and extent of acetone generation and to explore its detection in the urine. Maximal serum isopropyl alcohol concentrations were observed by 30 minutes after ingestion of approximately 1 oz 70% isopropyl alcohol (0.4 mL/kg), but maximal serum acetone concentrations were not recorded until at least four hours postingestion. Urine tested positive (small) for acetone within three hours of ingestion using Acetest urine testing tablets (Ames Labs, Elkhart, IN). It was concluded that acetonemia occurs early after ingestion of isopropyl alcohol and increases as serum isopropyl alcohol concentrations decline. In addition, acetonuria may be qualitatively measured by three hours postingestion with rapid urine screening tests and may remain positive for 24 hours.
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PMID:The generation of acetonemia/acetonuria following ingestion of a subtoxic dose of isopropyl alcohol. 291 47

Investigations of renal function have been done in healthy ewes in different stages of reproduction, and after food restriction, as well as in ewes sick with ketosis, hypocalcemia, rumen acidosis and different nephropathies. The determination was based on the estimated weight dependent endogenous creatinine excretion (E). A reference population of 56 healthy non or early pregnant ewes (before day 120 of pregnancy) was used as control. Late pregnancy (121.-149. day, n = 14) and lactation (n = 14) lead to higher renal creatinine-clearance (approximately GFR). Food restriction in all stages of pregnancy was followed by lower plasma concentrations of potassium, calcium, magnesium and glucose, and a reduced fractional excretion of potassium, calcium and magnesium. Pregnancy and especially food restriction caused a marked rise of the 3-OH-hydroxybutyrate values in the plasma and a significant acetonuria. After withdrawal of feed in lactating sheep, in opposition to pregnant sheep, the plasma values of phosphate were higher. In ketotic sheep (n = 43) a failure of renal function could not be demonstrated, the pronounced acetonuria could be explained by acetonemia. In hypocalcemia (n = 23) disturbance of creatinine-clearance and tubular reabsorption of sodium, potassium, glucose and 3-OH-butyrate could be seen. Glucosuria and acetonuria were caused by increased plasma concentrations and reduced tubular reabsorption. In rumen acidosis (n = 10) disturbances of low degree of GFR and reabsorption could be seen, glucosuria was mainly due to hyperglycemia.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Clinical studies of kidney function in sheep. II. Effect of pregnancy, lactation and feed restriction and metabolic diseases on kidney function]. 772 May 46