Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0155339 (Brown)
12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cells keep their cholesterol in balance by sensing its level in the endoplasmic reticulum and transducing this information into the expression of multiple homeostatic genes. Two recent papers from the Brown and Goldstein laboratory provide important new insights into how an integral ER protein, SCAP, mediates this process.
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PMID:SCAP, an ER sensor that regulates cell cholesterol. 1236 93