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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The incidence of stressful life events in the six months previous to psychiatric hospitalization is studied in a group of patients allotted to different diagnostic categories but which held in common that they were at their first episode of inpatient treatment. The presence of early life events during childhood and of chronic stress during the last year is also investigated. The different kind of responses to LE are described, classified in several categories. The incidence of LE in the patients is compared with that of a group of acute traumatologic hospital inpatients. In every case it has been used the Paykel LE rating scale, the Brown and Harris interview schedule and the GAF. Results are analyzed and their implications in preventive and treatment programs in Mental Health are discussed.
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PMID:[Stress factors in psychiatric hospitalization]. 160 3

A number of authors have indicated in recent years that the course of depression is not as favourable as previously expected. Research conducted in order to identify predictors of recovery has shown widely different results. In this paper a sample of 90 consecutive patients with non-chronic major depressive disorders (index episode < 6 months) attending four mental health centres in Madrid were followed up prospectively for 6 months, and clinical social and cognitive variables were studied. The patients were treated pharmacologically and controlled. The rate of recovery was measured according to the Hamilton Rating Scale for Depression (HAM-D). Other tools used were: Life Events and Chronic Difficulties, Global Assessment Functioning in the 6 months prior to the onset of episode, Brown Rating Scale for Self-Esteem and Mannheim Interview of Social Support. The results showed that 41 cases recovered (HAM-D score < 8), 29 cases achieved a partial remission, and major depressive disorder persisted in 17 cases (HAM-D score > or = 18). The presence of personality disorders, having suffered a previous episode, GAF score and some aspects of social support were the variables most associated with non full remission in the logistic regression analysis. Personality disorders and the initial HAM-D score were related to non-improvement. Some clinical and cognitive variables maintain a weak relation to outcome and are rejected in logistic regression. This study emphasizes the relationship of personality, and social variables such as social support and previous global functioning, with incomplete recovery in major depression.
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PMID:Factors associated with outcome in major depression: a 6-month prospective study. 980 23

The aim of this study is to investigate the possible different effects of obsessive compulsive disorder (OCD) and obsessive compulsive symptoms (OCS) on schizophrenia illness in regard to clinical characteristics such as severity of symptomatology. We included 184 patients with schizophrenia on monotherapy with a stable dose of antipsychotics for at least three months. Severity of clinical symptoms was evaluated by Positive and Negative Syndrome Scale. OCS was examined by Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Checklist. We also assessed OCD by using Y-BOCS. Seventeen percent of the patients were diagnosed with current OCD, while 17.4% of the patients were found to have OCS without OCD. Age of onset for OCD group was earlier than non-OCS group (p=0.007). The rate of occupation was higher (p=0.001), prevalence of other comorbid psychiatric disorders was lower (p=0.05), number of hospitalization was lower (p=0.03), GAF score was higher (p=0.03) and duration of education was longer (p=0.02) in the OCS group than in the non-OCS group. The rate of occupation was higher (p=0.04) and that rate of comorbid psychiatric disorders was lower (p=0.01) in the OCS group than in the OCD group. We found more OCS in patients using atypical antipsychotics (p=0.03). Our findings suggest that OCD and OCS might have different effects on schizophrenia.
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PMID:Obsessive compulsive disorder and symptoms may have different effects on schizophrenia. 2081 15