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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effectiveness of 'Fertivet' (180 mg. Cisclomiphene Citrate and 120 mg. Transclomiphene citrate mixture) in the induction of estrus and fertility was tested on sixteen anestrous cows. Of all the animals treated 14 (97.5%) expressed estrus and 8 (57.1%) conceived. Among the three breeds of cows treated, 5 out of 5 Brown Swiss, 4 out of 5 Jersey cross breeds and 5 out of 6 Sahiwal (Zebu) cows expressed estrus. These results indicate the usefulness of 'Fertivet' in the induction of fertile estrus in cows.
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PMID:Induction of estrus in anestrous cows treated with 'Fertivet'. 1672 84

Prior to 1978, the therapeutic offerings available to couples afflicted with infertility were painfully limited. Indeed, there was precious little one could offer Lesley and John Brown in their desperation. Anovulatory infertility was managed with ovulation induction using Clomiphene Citrate and Human Menopausal Gonadotropins. Anatomic infertility was addressed by increasingly sophisticated if marginally effective microsurgical approaches. The therapy of male infertility, still in its infancy, was commonly handled through cervical or intrauterine insemination including the use of donor sperm. The road traveled by Mrs. Brown radically altered this hope-limited landscape. A trailblazer to the millions who followed, Mrs. Brown played a key role in the abolition of the scourge of infertility. In this communication we trace in some detail the singular story of Mrs. Lesley Brown and the all-important legacy thereof. In doing so, we wish to pay tribute to this remarkable individual and her contributions to one of the most compelling scientific and medical breakthroughs of the 20th century.
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PMID:Barrenness vanquished: the legacy of Lesley Brown. 2367 13