Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0155339 (Brown)
 12,436 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The technique and results of simultaneous superior oblique tenotomy and 14-mm inferior oblique recession for true Brown's syndrome are presented for 16 eyes of 13 patients. A good or excellent result was achieved in 15 of 16 eyes (94%). Reoperation for overcorrection was not necessary; however, repeat tenotomy was required in two cases. Inferior oblique underaction was present in 12 of 16 eyes (75%) in the early postoperative period; however, elevation in adduction improved over time. At most recent examination, 92% of eyes demonstrated greater than 25 degrees elevation in adduction. Underaction of the superior oblique occurred in 3 of 16 eyes (19%). A simultaneous superior oblique tenotomy and inferior oblique recession is recommended in all patients selected to undergo surgery for true Brown's syndrome to prevent reoperation for iatrogenic superior oblique palsy.
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PMID:Simultaneous superior oblique tenotomy and inferior oblique recession in Brown's syndrome. 365 65

We investigated the etiology and incidence of 100 cases of inferior oblique underaction. The difference between congenital and acquired underaction was discussed using Awaya's New Cyclo Tests (NCT) to examine cyclodeviation qualitatively and quantitatively. Inferior oblique underaction had been considered more frequently congenital than acquired. However, 63.0% of our cases were proved to be acquired. The congenital cases were Brown's syndrome and cases of unknown causes and the acquired cases were mainly of myasthenic or traumatic origin. The results of the NCT examination were as follows: incyclodeviation or no cyclodeviation was encountered in all cases of congenital underaction except for one postoperative case, but excyclodeviation rather than incyclodeviation occurred in cases of acquired underaction, which showed ocular torticollis to the side of the paretic eye. This result suggested that some other muscles were involved in acquired cases of seemingly isolated inferior oblique underaction, especially in myasthenia gravis. A diagnosis of myasthenia gravis should be considered first when an acquired inferior oblique underaction occurs with association of excyclodeviation demonstrated by the NCT as well as Cogan's lid twitch sign.
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PMID:[Inferior oblique underaction]. 836 87